panaxydol

(3R)-8-[(2R,3S)-3- heptyloxiran-2-yl]oct-1-en-4,6-diyn-3-ol 1- octene-4,6-diyn-3-ol, 8-(3-heptyloxiranyl)- PubMed: Inhibitory Effects of Polyacetylene Compounds from Panax ginseng on Neurotrophin Receptor-Mediated Hair Growth. PubMed: Isolation and characterization of bioactive polyacetylenes Panax ginseng Meyer roots. PubMed: Determining the mode of action of anti-mycobacterial C17 diyne natural products using expression profiling: evidence for fatty acid biosynthesis inhibition. PubMed: Panaxydol, a component of Panax ginseng, induces apoptosis in cancer cells through EGFR activation and ER stress and inhibits tumor growth in mouse models. PubMed: Gas chromatography/mass spectrometry-based metabolic profiling and differentiation of ginseng roots according to cultivation age using variable selection. PubMed: Biosynthesis of panaxynol and panaxydol in Panax ginseng. PubMed: Anti-mycobacterial diynes from the Canadian medicinal plant Aralia nudicaulis. PubMed: [Simultaneous determination of panaxynol and panaxydol in fibrous root of Panax ginseng by HPLC]. PubMed: Induction of apoptosis in human promyelocytic leukemia HL60 cells by panaxynol and panaxydol. PubMed: Induction of differentiation by panaxydol in human hepatocarcinoma SMMC-7721 cells via cAMP and MAP kinase dependent mechanism. PubMed: Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidase-dependent generation of reactive oxygen species. PubMed: Quantitative comparison of ginsenosides and polyacetylenes in wild and cultivated American ginseng. PubMed: Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation. PubMed: Panaxydol inhibits the proliferation and induces the differentiation of human hepatocarcinoma cell line HepG2. PubMed: Rapid method for simultaneous determination of flavonoid, saponins and polyacetylenes in folium ginseng and radix ginseng by pressurized liquid extraction and high-performance liquid chromatography coupled with diode array detection and mass spectrometry. PubMed: Phosphatidylinositol 3-kinase activity is required for the induction of differentiation in C6 glioma cells by panaxydol. PubMed: Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds. PubMed: Cyclic AMP-dependent regulation of differentiation of rat C6 glioma cells by panaxydol. PubMed: Panaxydol treatment enhances the biological properties of Schwann cells in vitro. PubMed: Effect of panaxydol on hypoxia-induced cell death and expression and secretion of neurotrophic factors (NTFs) in hypoxic primary cultured Schwann cells. PubMed: Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro. PubMed: Panaxydol and panaxynol protect cultured cortical neurons against Abeta25-35-induced toxicity. PubMed: Growth inhibition and induction of differentiation by panaxydol in rat C6 glioma cells. PubMed: Quantification of two polyacetylenes in Radix Ginseng and roots of related Panax species using a gas chromatography-mass spectrometric method. PubMed: Induction of apoptosis in rat C6 glioma cells by panaxydol. PubMed: Simultaneous determination of ginsenosides and polyacetylenes in American ginseng root (Panax quinquefolium L.) by high-performance liquid chromatography. PubMed: Structural changes of polyacetylenes in American ginseng root can be observed in situ by using Raman spectroscopy. PubMed: Protective effect of panaxydol and panaxynol on sodium nitroprusside-induced apoptosis in cortical neurons. PubMed: Polyacetylenes in hairy roots of a panax hybrid. PubMed: Determination of polyacetylenes and ginsenosides in Panax species using high performance liquid chromatography. PubMed: Inducible nitric oxide synthase inhibitors from Saposhnikovia divaricata and Panax quinquefolium. PubMed: Induction of G(1) cell cycle arrest and p27(KIP1) increase by panaxydol isolated from Panax ginseng. PubMed: Synthesis of ginseng diyne analogues and their antiproliferative activity against L1210 cells. PubMed: Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells. PubMed: Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase. PubMed: Screening of polyacetylenic alcohols in crude drugs using the ELISA for panaxytriol. PubMed: [Relationship between antiproliferative activity of acetylenic alcohol, panaxydol, and its affinity for target cell membrane]. PubMed: The first specific antibody against cytotoxic polyacetylenic alcohol, panaxynol. PubMed: Cytotoxic activity of polyacetylene compounds in Panax ginseng C. A. Meyer. PubMed: [Acetylpanaxydol and panaxydolchlorohydrin, two new polyenes from Korean ginseng with cytotoxic activity against L1210 cells]. PubMed: [Relation between structure and cytotoxic activity of panaxydol analogs against L1210 cells].