sesamolin

CAS: 526-07-8 C20 H18 O7 MW: 370.35786000

Identification

Namesesamolin
CAS Number526-07-8
FDA UNII7A90TJ149G
Molecular FormulaC20 H18 O7
Molecular Weight370.35786000
Nikkaji NumberJ9.611C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 4.87 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for sesamolin usage levels up tonot for fragrance use.
Recommendation for sesamolin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

sesamum indicum seed

Synonyms

5-[[(3S,3aR,6R,6aR)-3-(1,3- benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole 1,3- benzodioxole, 5-(4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-, (1S-(1alpha,3a alpha,4alpha,6a alpha))- PubMed: Quality properties of puffed corn snacks incorporated with sesame seed powder. PubMed: Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame. PubMed: Encapsulation of sesamol in phosphatidyl choline micelles: Enhanced bioavailability and anti-inflammatory activity. PubMed: Manufacture of low-benzo(a)pyrene sesame seed (Sesamum indicum L.) oil using a self-designed apparatus. PubMed: A Nuclear Magnetic Resonance Spectroscopy Approach to Discriminate the Geographic Origin of Roasted Asian Sesame Oils. PubMed: Determination and purification of sesamin and sesamolin in sesame seed oil unsaponified matter using reversed-phase liquid chromatography coupled with photodiode array and tandem mass spectrometry and high-speed countercurrent chromatography. PubMed: Magnetic solid-phase extraction based on graphene oxide for the determination of lignans in sesame oil. PubMed: Discovery of a sesamin-metabolizing microorganism and a new enzyme. PubMed: Synthesis of furofuran lignans as antidiabetic agents simultaneously achieved by inhibiting α-glucosidase and free radical. PubMed: Inhibition of lipoxygenase by sesamol corroborates its potential anti-inflammatory activity. PubMed: Effects of Sesaminol Feeding on Brain Aβ Accumulation in a Senescence-Accelerated Mouse-Prone 8. PubMed: Preparative separation of sesamin and sesamolin from defatted sesame meal via centrifugal partition chromatography with consecutive sample injection. PubMed: Accelerated separation of GC-amenable lipid classes in plant oils by countercurrent chromatography in the co-current mode. PubMed: Combined Analysis of Stable Isotope, (1)H NMR, and Fatty Acid To Verify Sesame Oil Authenticity. PubMed: Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt's lymphoma cells. PubMed: Evaluation of plant growth regulatory activity of furofuran lignan bearing a 7,9':7',9-diepoxy structure using optically pure (+)- and (-)-enantiomers. PubMed: Characterization of the Fluorescent Spectra and Intensities of Various Lignans: Application to HPLC Analysis with Fluorescent Detection†. PubMed: Bioactive lignans from sesame (Sesamum indicum L.): evaluation of their antioxidant and antibacterial effects for food applications. PubMed: Tracking sesamin synthase gene expression through seed maturity in wild and cultivated sesame species--a domestication footprint. PubMed: Comparative effects of sesame seeds differing in lignan contents and composition on fatty acid oxidation in rat liver. PubMed: The relationship of antioxidant components and antioxidant activity of sesame seed oil. PubMed: Value addition in sesame: A perspective on bioactive components for enhancing utility and profitability. PubMed: Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice. PubMed: Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-γ. PubMed: Sesamin and sesamolin as unexpected contaminants in various cold-pressed plant oils: NP-HPLC/FLD/DAD and RP-UPLC-ESI/MS(n) study. PubMed: Lignans of sesame: purification methods, biological activities and biosynthesis--a review. PubMed: Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia. PubMed: Penicillium sp. mitigates Fusarium-induced biotic stress in sesame plants. PubMed: Tissue distribution and cytochrome P450 inhibition of sesaminol and its tetrahydrofuranoid metabolites. PubMed: Prophylactic sesame oil attenuates sinusoidal obstruction syndrome by inhibiting matrix metalloproteinase-9 and oxidative stress. PubMed: Therapeutic oral sesame oil is ineffectual against monocrotaline-induced sinusoidal obstruction syndrome in rats. PubMed: Analysis of expression sequence tags from a full-length-enriched cDNA library of developing sesame seeds (Sesamum indicum). PubMed: Sesamolinol glucoside, disaminyl ether, and other lignans from sesame seeds. PubMed: [Nutritional value of sesame seeds]. PubMed: Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation. PubMed: Experimental antithrombotic effects of sesame seed whole grains and extracts. PubMed: Mechanism of oil-pulling therapy - in vitro study. PubMed: Identification of methanol-soluble compounds in sesame and evaluation of antioxidant potential of its lignans. PubMed: Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis. PubMed: Estrogenic activities of sesame lignans and their metabolites on human breast cancer cells. PubMed: Sesame seed lignans: potent physiological modulators and possible ingredients in functional foods & nutraceuticals. PubMed: Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors. PubMed: Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts. PubMed: Analysis of antioxidant activities in vegetable oils and fat soluble vitamins and biofactors by the PAO-SO method. PubMed: Identification and characterization of sesaminol metabolites in the liver. PubMed: Effect of infrared heating on the formation of sesamol and quality of defatted flours from Sesamum indicum L. PubMed: Lipid metabolism and nutrigenomics - impact of sesame lignans on gene expression profiles and fatty acid oxidation in rat liver. PubMed: Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver. PubMed: Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus. PubMed: Elimination and metabolism of sesamol, a bioactive compound in sesame oil, in rats. PubMed: Comparison of atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for the detection of lignans from sesame seeds. PubMed: Bioavailability and tissue distribution of sesamol in rat. PubMed: Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects. PubMed: HPTLC fingerprinting and quantification of lignans as markers in sesame oil and its polyherbal formulations. PubMed: Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats. PubMed: Synergistic antimicrobial activities of phytoestrogens in crude extracts of two sesame species against some common pathogenic microorganisms. PubMed: Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. PubMed: Nondestructive determination of lignans and lignan glycosides in sesame seeds by near infrared reflectance spectroscopy. PubMed: Oxidative toxicity in BV-2 microglia cells: sesamolin neuroprotection of H2O2 injury involving activation of p38 mitogen-activated protein kinase. PubMed: Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans. PubMed: Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. PubMed: Sesame lignans enhance antioxidant activity of vitamin E in lipid peroxidation systems. PubMed: Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected]. PubMed: Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia. PubMed: Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system. PubMed: Synthesis and antioxidant activity of oxygenated furofuran lignans. PubMed: Comparative analysis of expressed sequence tags from Sesamum indicum and Arabidopsis thaliana developing seeds. PubMed: Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells. PubMed: Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells. PubMed: Effects of dietary sesame seeds on plasma tocopherol levels. PubMed: Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver. PubMed: Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. PubMed: Quinoline alkaloids from Acronychia laurifolia. PubMed: Sesamolin inhibits lipid peroxidation in rat liver and kidney. PubMed: Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues. PubMed: Changes of ingredients in the process of cooking of sesame oil. PubMed: Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. PubMed: Is sesamol present in sesame oil? PubMed: Contact sensitivity to unsaponifiable substances in sesame oil. PubMed: Allergens in sesame oil contact dermatitis.