licoricidin
Identification
| Name | licoricidin |
| CAS Number | 30508-27-1 |
| FDA UNII | 929XTD20VK |
| Molecular Formula | C26 H32 O5 |
| Molecular Weight | 424.53704000 |
| Nikkaji Number | J885.811J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.001253 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for licoricidin usage levels up to | not for fragrance use. |
| Recommendation for licoricidin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4-((R)-7-
hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl)-2-((E)-3-methyl-but-2-enyl)-benzene-1,3-diol
4-[(3R)-7-
hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol
PubMed:
Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.
PubMed:
Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy.
PubMed:
Isolation and characterization of antimutagenic components of
Glycyrrhiza aspera
against
-methyl-
-nitrosourea.
PubMed:
Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS.
PubMed:
Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma.
PubMed:
Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts.
PubMed:
Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells.
PubMed:
Metabolites identification of bioactive licorice compounds in rats.
PubMed:
Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities.
PubMed:
Structures of new phenolics isolated from licorice, and the effectiveness of licorice phenolics on vancomycin-resistant Enterococci.
PubMed:
Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis.
PubMed:
Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice.
PubMed:
Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities.
PubMed:
Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification.
PubMed:
Licorice and its potential beneficial effects in common oro-dental diseases.
PubMed:
Modulation of matrix metalloproteinase and cytokine production by licorice isolates licoricidin and licorisoflavan A: potential therapeutic approach for periodontitis.
PubMed:
Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells.
PubMed:
Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus.
PubMed:
Antinephritis and radical scavenging activity of prenylflavonoids.
PubMed:
Anti-Helicobacter pylori flavonoids from licorice extract.
PubMed:
Antibacterial compounds of licorice against upper airway respiratory tract pathogens.
PubMed:
Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus.
PubMed:
Inhibition of lysoPAF acetyltransferase activity by components of licorice root.
PubMed:
Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins.
PubMed:
The chemical studies on the oriental plant drugs. XIX. Some new constituents of licorice root. 1. The structure of licoricidin.