licoricidin

CAS: 30508-27-1 C26 H32 O5 MW: 424.53704000

Identification

Namelicoricidin
CAS Number30508-27-1
FDA UNII929XTD20VK
Molecular FormulaC26 H32 O5
Molecular Weight424.53704000
Nikkaji NumberJ885.811J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.001253 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for licoricidin usage levels up tonot for fragrance use.
Recommendation for licoricidin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

glycyrrhiza glabra root glycyrrhiza uralensis root

Synonyms

4-((R)-7- hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl)-2-((E)-3-methyl-but-2-enyl)-benzene-1,3-diol 4-[(3R)-7- hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol PubMed: Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. PubMed: Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy. PubMed: Isolation and characterization of antimutagenic components of Glycyrrhiza aspera against -methyl- -nitrosourea. PubMed: Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS. PubMed: Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma. PubMed: Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. PubMed: Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells. PubMed: Metabolites identification of bioactive licorice compounds in rats. PubMed: Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities. PubMed: Structures of new phenolics isolated from licorice, and the effectiveness of licorice phenolics on vancomycin-resistant Enterococci. PubMed: Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. PubMed: Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice. PubMed: Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. PubMed: Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification. PubMed: Licorice and its potential beneficial effects in common oro-dental diseases. PubMed: Modulation of matrix metalloproteinase and cytokine production by licorice isolates licoricidin and licorisoflavan A: potential therapeutic approach for periodontitis. PubMed: Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells. PubMed: Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus. PubMed: Antinephritis and radical scavenging activity of prenylflavonoids. PubMed: Anti-Helicobacter pylori flavonoids from licorice extract. PubMed: Antibacterial compounds of licorice against upper airway respiratory tract pathogens. PubMed: Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus. PubMed: Inhibition of lysoPAF acetyltransferase activity by components of licorice root. PubMed: Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins. PubMed: The chemical studies on the oriental plant drugs. XIX. Some new constituents of licorice root. 1. The structure of licoricidin.