levistolide A

CAS: 89708-23-6 C24 H28 O4 MW: 380.48396000

Identification

Namelevistolide A
CAS Number89708-23-6
FDA UNIISearch
Molecular FormulaC24 H28 O4
Molecular Weight380.48396000
Nikkaji NumberJ470.616A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.2291 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for levistolide A usage levels up tonot for fragrance use.
Recommendation for levistolide A flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

ligusticum glaucescens

Synonyms

(Z,Z)- diligustilide 1H-5,10c- ethanonaphtho(1,2-c:7,8-c')difuran-3,10-dione, 1,8-dibutylidene-5,5a,6,7,8,10b-hexahydro-, (1Z,5S,5aS,8Z,10bS,10cs)- PubMed: Diligustilide releases H S and stabilizes S-nitrosothiols in ethanol-induced lesions on rat gastric mucosa. PubMed: Levistolide A Induces Apoptosis via ROS-Mediated ER Stress Pathway in Colon Cancer Cells. PubMed: The variation in the major constituents of the dried rhizome of Ligusticum chuanxiong (Chuanxiong) after herbal processing. PubMed: Gastroprotective effect of diligustilide isolated from roots of Ligusticum porteri coulter & rose (Apiaceae) on ethanol-induced lesions in rats. PubMed: Sulfur dioxide residue in sulfur-fumigated edible herbs: The fewer, the safer? PubMed: Vasorelaxant effects of Shunaoxin pill are mediated by NO/cGMP pathway, HO/CO pathway and calcium channel blockade in isolated rat thoracic aorta. PubMed: Screening anti-tumor compounds from Ligusticum wallichii using cell membrane chromatography combined with high-performance liquid chromatography and mass spectrometry. PubMed: Study on Pharmacokinetics of Three Preparations from Levistolide A by LC-MS-MS. PubMed: Optimization of high-pressure ultrasonic-assisted simultaneous extraction of six major constituents from Ligusticum chuanxiong rhizome using response surface methodology. PubMed: [Optimization of supercritical fluid extraction of bioactive components in Ligusticum chuanxiong by orthogonal array design]. PubMed: [Chemical change of chuanxiong raw materials during storage]. PubMed: Online isolation and purification of four phthalide compounds from Chuanxiong rhizoma using high-speed counter-current chromatography coupled with semi-preparative liquid chromatography. PubMed: Antimycobacterials from lovage root (Ligusticum officinale Koch). PubMed: Quantitative HPLC method for determining two of the major active phthalides from Ligusticum porteri roots. PubMed: Two phthalide dimers from the radix of Angelica sinensis. PubMed: Identification of the absorbed components and metabolites in rat plasma after oral administration of Rhizoma Chuanxiong decoction by HPLC-ESI-MS/MS. PubMed: [Studies on the chemical constituents of Ligusticum sinense]. PubMed: [Studies on the chemical constituents of the root and rhizoma of Ligusticum jeholense]. PubMed: Identification and determination of the major constituents in Traditional Chinese Medicinal formula Danggui-Shaoyao-San by HPLC-DAD-ESI-MS/MS. PubMed: [Study on biligustilides from Angelica sinensis]. PubMed: Levistolide A overcomes P-glycoprotein-mediated drug resistance in human breast carcinoma cells. PubMed: Studies on antiproliferative effects of phthalides from Ligusticum chuanxiong in hepatic stellate cells. PubMed: [Studies on chemical constituents from Ligusticum glaucescens Franch]. PubMed: Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong). PubMed: Dimeric progestins from rhizomes of Ligusticum chuanxiong. PubMed: Development of high-performance liquid chromatographic fingerprints for distinguishing Chinese Angelica from related umbelliferae herbs. PubMed: [New dimeric phthalide derivative from Angelica sinensis]. PubMed: [Study on fingerprint of rhizoma chuanxiong by HPLC-DAD-MS]. PubMed: Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry.