helveticoside
deglucoerysimoside
Identification
| Name | helveticoside |
| CAS Number | 630-64-8 |
| EINECS | 211-140-9 |
| FDA UNII | 52OAE3C457 |
| Molecular Formula | C29 H42 O9 |
| Molecular Weight | 534.64654000 |
| MDL Number | MFCD00079343 |
| Nikkaji Number | J15.794E |
| XlogP3 | 0.30 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 237.5 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for helveticoside usage levels up to | not for fragrance use. |
| Recommendation for helveticoside flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
card-20(22)-enolide, 3-((2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3-beta,5-beta)-
deglucoerysimoside
(3beta,5beta)-3-((2,6-
dideoxy-beta-D -ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxocard-20(22)-enolide
(3S,5S,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6R)-4,5-
dihydroxy-6-methyloxan-2-yl]oxy-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
erysimotoxin
PubMed:
Helveticoside is a biologically active component of the seed extract of Descurainia sophia and induces reciprocal gene regulation in A549 human lung cancer cells.
PubMed:
Ethanol Extract of Lepidium apetalum Seed Elicits Contractile Response and Attenuates Atrial Natriuretic Peptide Secretion in Beating Rabbit Atria.
PubMed:
Protein-protein interaction network analysis in chronic obstructive pulmonary disease.
PubMed:
LC-ESI-MS/MS characterization of strophanthin-K.
PubMed:
Cardenolides from Adonis aestivalis.
PubMed:
[Pharmacological effect of substituted helveticoside and helveticosol derivatives with special reference to cyclopentanonehelveticoside and light-induced transformation products of strophantidine].
PubMed:
[Metabolism of helveticoside and helveticosol derivatives].
PubMed:
[Improvement in the absorption of helveticoside and helveticosol by substitution of the hydroxyl hydrogen on digitoxose].
PubMed:
[ON STRUCTURE-ACTIVITY RELATIONS AND QUALITATIVE DISTINCTIONS OF EFFICACY BETWEEN G-STROPHANTHIN, CONVALLATOXIN, HELVETICOSIDE AND CYMARINE].
PubMed:
[STABILITY OF CARDENOLIDES OF THE STROPHANTHIDIN TYPE IN INJECTABLE PREPARATIONS. III. PREPARATIONS OF STABLE INJECTABLE SOLUTIONS OF HELVETICOSIDE].
PubMed:
[The cardiotoxic activity of helveticoside, a cardiac glycoside from Erysimum canescens Roth].
PubMed:
[Effect of oxyphylline on the cardiotoxic activity of convallatoxin and helveticoside and on their action on the heart-lung preparation of the cat].