germanicol
Identification
| Name | germanicol |
| CAS Number | 465-02-1 |
| FDA UNII | 7NEX9512DZ |
| Molecular Formula | C30 H50 O |
| Molecular Weight | 426.72770000 |
| Nikkaji Number | J12.058H |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 9.552e-005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for germanicol usage levels up to | not for fragrance use. |
| Recommendation for germanicol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(3S,4aR,6aS,6aR,6bR,8aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-
octamethyl-1,2,3,4a,5,6,6a,7,8,9,10,13,14,14a-tetradecahydropicen-3-ol
olean-18-en-3-ol, (3beta)-
PubMed:
Strictly Conserved Residues in Euphorbia tirucalli β-Amyrin Cyclase: Trp612 Stabilizes Transient Cation through Cation-Ï Interaction and CH-Ï Interaction of Tyr736 with Leu734 Confers Robust Local Protein Architecture.
PubMed:
Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migration.
PubMed:
Multifunctional oxidosqualene cyclases and cytochrome P450 involved in the biosynthesis of apple fruit triterpenic acids.
PubMed:
Cytotoxic biomonitored study of Euphorbia umbellata (Pax) Bruyns.
PubMed:
Chemical Constituents of Lecythispisonis (Lecythidaceae)--A New Saponin and Complete 1H and 13C Chemical Shift Assignments.
PubMed:
Phytochemical and pharmacological study of Ficus palmata growing in Saudi Arabia.
PubMed:
Changes in the triterpenoid content of cuticular waxes during fruit ripening of eight grape (Vitis vinifera) cultivars grown in the Upper Rhine Valley.
PubMed:
Klodorone A and klodorol A: new triterpenes from Kleinia odora.
PubMed:
[Triterpene compounds of Ainsliaea yunnanensis].
PubMed:
Effect of cation-Ï interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of β-amyrin synthase from Euphorbia tirucalli L.
PubMed:
[Chemical constituents of Psammosilene tunicoides and bacteriostatic activity].
PubMed:
Triterpenoid profile of flower and leaf cuticular waxes of heather Calluna vulgaris.
PubMed:
Isolation and characterization of new ceramides from aerial parts of Lepidaploa cotoneaster.
PubMed:
Source correlation of biomarkers in a mangrove ecosystem on Santa Catarina Island in southern Brazil.
PubMed:
Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD.
PubMed:
Antibacterial activity of the essential oils of Pistacia lentiscus used in Moroccan folkloric medicine.
PubMed:
A new triterpene from Barringtonia asiatica.
PubMed:
New triterpenes from Barringtonia asiatica.
PubMed:
Antiinflammatory properties of Morus nigra leaves.
PubMed:
Occurrence and sources of triterpenoid methyl ethers and acetates in sediments of the cross-river system, southeast Nigeria.
PubMed:
Composition of the epicuticular and intracuticular wax layers on Kalanchoe daigremontiana (Hamet et Perr. de la Bathie) leaves.
PubMed:
Development of the cuticular wax during growth of Kalanchoe daigremontiana (Hamet et Perr. de la Bathie) leaves.
PubMed:
Rapid and enantioselective synthetic approaches to germanicol and other pentacyclic triterpenes.
PubMed:
Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae.
PubMed:
Two new 18-en-oleane derivatives from marine mangrove plant, Barringtonia racemosa.
PubMed:
Antitumor and antiinflammatory constituents from Celtis sinensis.
PubMed:
Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum.
PubMed:
Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol.
PubMed:
Koelpinin-A, B and C--three triterpenoids from Koelpinia linearis.
PubMed:
Molluscicidal constituents of Marsypianthes chamaedrys.
PubMed:
Triterpenoid compounds from Araujia sericifera B. Effects on the isolated guinea pig ileum.
PubMed:
Antiplasmodial triterpene from Vernonia brasiliana.
PubMed:
Linear, steroidal, and triterpene esters, and steryl glycosides from Festuca argentina.
PubMed:
[Triterpene constituents from Euphorbia nematocypha Hand-Mazz].