cucurbitacin C
Identification
| Name | cucurbitacin C |
| CAS Number | 5988-76-1 |
| FDA UNII | 938A8MM70H |
| Molecular Formula | C32 H48 O8 |
| Molecular Weight | 560.72816000 |
| Nikkaji Number | J8.327E |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.7021 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cucurbitacin C usage levels up to | not for fragrance use. |
| Recommendation for cucurbitacin C flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
[(E,6R)-6-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-
dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
19-
norlanosta-5,23-diene-11,22-dione, 25-(acetyloxy)-3,16,20-trihydroxy-9-(hydroxymethyl)-, (3beta,9beta,10alpha,16alpha,23E)- (9CI)
PubMed:
Conspecific and Heterospecific Aboveground Herbivory Both Reduce Preference by a Belowground Herbivore.
PubMed:
Plant science. Biosynthesis, regulation, and domestication of bitterness in cucumber.
PubMed:
23,24-Dihydrocucurbitacin C: a new compound regarded as the next metabolite of cucurbitacin C.
PubMed:
Linking agricultural practices, mycorrhizal fungi, and traits mediating plant-insect interactions.
PubMed:
Cucurbitacin D induces fetal hemoglobin synthesis in K562 cells and human hematopoietic progenitors through activation of p38 pathway and stabilization of the γ-globin mRNA.
PubMed:
Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration.
PubMed:
New cucurbitane-type triterpenoids from Bryonia aspera.
PubMed:
Studies on the cytotoxicity of cucurbitacins isolated from Cayaponia racemosa (Cucurbitaceae).
PubMed:
Role of cucurbitacin C in resistance to spider mite (Tetranychus urticae) in cucumber (Cucumis sativus L.).