epidermin

3- methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutanenitrile PubMed: Carboxyl Analogue of Mutacin 1140, a Scaffold for Lead Antibacterial Discovery. PubMed: Fibrous Protein Structures: Hierarchy, History and Heroes. PubMed: Biosynthesis of the leucine derived α-, β- and γ-hydroxynitrile glucosides in barley (Hordeum vulgare L.). PubMed: Whole-Genome Sequence of Staphylococcus epidermidis Tü3298. PubMed: Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis. PubMed: Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP. PubMed: Epidermin and gallidermin: Staphylococcal lantibiotics. PubMed: Site-directed mutations in the lanthipeptide mutacin 1140. PubMed: Isolation, biochemical characterization, and cloning of a bacteriocin from the poultry-associated Staphylococcus aureus strain CH-91. PubMed: Hyicin 3682, a bioactive peptide produced by Staphylococcus hyicus 3682 with potential applications for food preservation. PubMed: Biosynthesis of aminovinyl-cysteine-containing peptides and its application in the production of potential drug candidates. PubMed: Xenobiotic metabolism gene expression in the EpiDermin vitro 3D human epidermis model compared to human skin. PubMed: Staphylococcal antimicrobial peptides: relevant properties and potential biotechnological applications. PubMed: Microtiter plate bioassay to monitor the interference of antibiotics with the lipid II cycle essential for peptidoglycan biosynthesis. PubMed: Activity of staphylococcal bacteriocins against Staphylococcus aureus and Streptococcus agalactiae involved in bovine mastitis. PubMed: Peptide-like substances as antimicrobial barriers to Corynebacterium sp. adhesion to silicone catheters. PubMed: Comparative genomics of Canadian epidemic lineages of methicillin-resistant Staphylococcus aureus. PubMed: Bacteriocins Pep5 and epidermin inhibit Staphylococcus epidermidis adhesion to catheters. PubMed: Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies. PubMed: Bacteriocins as alternative agents for control of multiresistant staphylococcal strains. PubMed: Control of antimicrobial peptide synthesis by the agr quorum sensing system in Staphylococcus epidermidis: activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing. PubMed: Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate. PubMed: Chemistry and biology of the ramoplanin family of peptide antibiotics. PubMed: Mode of action of modified and unmodified bacteriocins from Gram-positive bacteria. PubMed: Combination of antibiotic mechanisms in lantibiotics. PubMed: Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry to reveal the substrate specificity of the peptidyl-cysteine decarboxylase EpiD. PubMed: Leucine-derived cyano glucosides in barley. PubMed: Multiple activities in lantibiotics--models for the design of novel antibiotics? PubMed: The flavoprotein MrsD catalyzes the oxidative decarboxylation reaction involved in formation of the peptidoglycan biosynthesis inhibitor mersacidin. PubMed: Molecular characterization of the 4'-phosphopantothenoylcysteine decarboxylase domain of bacterial Dfp flavoproteins. PubMed: Comparison of the activity spectra against pathogens of bacterial strains producing a mutacin or a lantibiotic. PubMed: Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis. PubMed: Dual role of GdmH in producer immunity and secretion of the Staphylococcal lantibiotics gallidermin and epidermin. PubMed: Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate. PubMed: Covalent structure of mutacin 1140 and a novel method for the rapid identification of lantibiotics. PubMed: Posttranslationally modified bacteriocins--the lantibiotics. PubMed: Purification and biochemical characterization of mutacin I from the group I strain of Streptococcus mutans, CH43, and genetic analysis of mutacin I biosynthesis genes. PubMed: Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis. PubMed: New insights into the mechanism of action of lantibiotics--diverse biological effects by binding to the same molecular target. PubMed: Chemistry, biochemistry, nutrition, and microbiology of lysinoalanine, lanthionine, and histidinoalanine in food and other proteins. PubMed: Purification of mutacin III from group III Streptococcus mutans UA787 and genetic analyses of mutacin III biosynthesis genes. PubMed: Lysinoalanine in food and in antimicrobial proteins. PubMed: Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics. PubMed: Producer self-protection against the lantibiotic epidermin by the ABC transporter EpiFEG of Staphylococcus epidermidis Tü3298. PubMed: Genetic and biochemical analysis of mutacin 1140, a lantibiotic from Streptococcus mutans. PubMed: In vivo reaction of affinity-tag-labelled epidermin precursor peptide with flavoenzyme EpiD. PubMed: Purification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans. PubMed: Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. PubMed: Secretion of the lantibiotics epidermin and gallidermin: sequence analysis of the genes gdmT and gdmH, their influence on epidermin production and their regulation by EpiQ. PubMed: The enethiolate anion reaction products of EpiD. Pka value of the enethiol side chain is lower than that of the thiol side chain of peptides. PubMed: Isolation of a new epidermin variant from two strains of Staphylococcus epidermidis--frequency of lantibiotic production in coagulase-negative staphylococci. PubMed: Inducible production and cellular location of the epidermin biosynthetic enzyme EpiB using an improved staphylococcal expression system. PubMed: Genetic determinants for the biosynthesis of nisin, a bacteriocin produced by Lactococcus lactis. PubMed: Expression, purification, and characterization of EpiC, an enzyme involved in the biosynthesis of the lantibiotic epidermin, and sequence analysis of Staphylococcus epidermidis epiC mutants. PubMed: Comparison of lantibiotic gene clusters and encoded proteins. PubMed: Protein engineering of lantibiotics. PubMed: Immunity to lantibiotics. PubMed: Post-translational modifications of lantibiotics. PubMed: The biosynthesis of the lantibiotics epidermin, gallidermin, Pep5 and epilancin K7. PubMed: Analysis of the Staphylococcus epidermidis genes epiF, -E, and -G involved in epidermin immunity. PubMed: Serine protease EpiP from Staphylococcus epidermidis catalyzes the processing of the epidermin precursor peptide. PubMed: Isolation and characterization of genetically engineered gallidermin and epidermin analogs. PubMed: Elucidation of the primary structure of the lantibiotic epilancin K7 from Staphylococcus epidermidis K7. Cloning and characterisation of the epilancin-K7-encoding gene and NMR analysis of mature epilancin K7. PubMed: Oxidative decarboxylation of peptides catalyzed by flavoprotein EpiD. Determination of substrate specificity using peptide libraries and neutral loss mass spectrometry. PubMed: Fast atom bombardment mass spectrometry of some lantibiotics. PubMed: Mass spectroscopic analysis of a novel enzymatic reaction. Oxidative decarboxylation of the lantibiotic precursor peptide EpiA catalyzed by the flavoprotein EpiD. PubMed: Staphylococcin 1580 is identical to the lantibiotic epidermin: implications for the nature of bacteriocins from gram-positive bacteria. PubMed: Growth phase-dependent regulation and membrane localization of SpaB, a protein involved in biosynthesis of the lantibiotic subtilin. PubMed: Gene-encoded antibiotics made in bacteria. PubMed: [Lantibiotics, a class of ribosomally synthesized peptide antibiotics]. PubMed: Purification and characterization of EpiA, the peptide substrate for post-translational modifications involved in epidermin biosynthesis. PubMed: Regulation of epidermin biosynthetic genes by EpiQ. PubMed: Biosynthesis of the lantibiotic nisin: genomic organization and membrane localization of the NisB protein. PubMed: Purification and characterization of EpiD, a flavoprotein involved in the biosynthesis of the lantibiotic epidermin. PubMed: [Lantibiotics]. PubMed: Lantibiotic-mediated anti-lactobacillus activity of a vaginal Staphylococcus aureus isolate. PubMed: Genetic analysis of epidermin biosynthetic genes and epidermin-negative mutants of Staphylococcus epidermidis. PubMed: Analysis of genes involved in the biosynthesis of lantibiotic epidermin. PubMed: Analysis of genes involved in biosynthesis of the lantibiotic subtilin. PubMed: Comparative studies on the fermentative production of lantibiotics by staphylococci. PubMed: Structural gene isolation and prepeptide sequence of gallidermin, a new lanthionine containing antibiotic. PubMed: Nisin, a peptide antibiotic: cloning and sequencing of the nisA gene and posttranslational processing of its peptide product. PubMed: Structure, expression, and evolution of a gene encoding the precursor of nisin, a small protein antibiotic. PubMed: Gallidermin: a new lanthionine-containing polypeptide antibiotic. PubMed: Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings. PubMed: Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic. PubMed: A comparative study of myosins and prekeratin in epithelial cells of methacarn-fixed tissues. PubMed: Mallory bodies: lesions of hepatocytes containing proteins of the keratin-myosin-epidermin group. PubMed: An electron microscope study of the epidermis of mammalian skin in thin sections. I. Dermo-epidermal junction and basal cell layer.