ganoderic acid A

(2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15- dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7beta,15alpha,25R)- PubMed: Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium. PubMed: Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures. PubMed: [Ganoderma triterpenoids from aqueous extract of Ganoderma lucidum]. PubMed: Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity. PubMed: One single standard substance for the simultaneous determination of 17 triterpenes in Ganoderma lingzhi and its related species using high-performance liquid chromatography. PubMed: Bacterial Expression of a Single-Chain Variable Fragment (scFv) Antibody against Ganoderic Acid A: A Cost-Effective Approach for Quantitative Analysis Using the scFv-Based Enzyme-Linked Immunosorbent Assay. PubMed: Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. PubMed: Network pharmacology analysis of the anti-cancer pharmacological mechanisms of Ganoderma lucidum extract with experimental support using Hepa1-6-bearing C57 BL/6 mice. PubMed: A Validated Reverse-Phase HPLC Method for Quantitative Determination of Ganoderic Acids A and B in Cultivated Strains of Ganoderma spp. (Agaricomycetes) Indigenous to India. PubMed: Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells. PubMed: Ganoderic acid targeting nuclear factor erythroid 2-related factor 2 in lung cancer. PubMed: Plasma and brain pharmacokinetics of ganoderic acid A in rats determined by a developed UFLC-MS/MS method. PubMed: Ganoderic Acid A Metabolites and Their Metabolic Kinetics. PubMed: Effect of Oral Coadministration of Ascorbic Acid with Ling Zhi Preparation on Pharmacokinetics of Ganoderic Acid A in Healthy Male Subjects: A Randomized Crossover Study. PubMed: Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. PubMed: Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study. PubMed: Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi. PubMed: Ganoderic Acid A Targeting β-Catenin in Wnt Signaling Pathway: In Silico and In Vitro Study. PubMed: Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay. PubMed: [Ganoderic acid A suppresses proliferation and invasion and induces apoptosis in human osteosarcoma cells]. PubMed: A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway. PubMed: A reproducible analytical system based on the multi-component analysis of triterpene acids in Ganoderma lucidum. PubMed: Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. PubMed: Polysaccharides-Rich Extract of Ganoderma lucidum (M.A. Curtis:Fr.) P. Karst Accelerates Wound Healing in Streptozotocin-Induced Diabetic Rats. PubMed: Production of Ginkgo leaf-shaped basidiocarps of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes), containing high levels of α- and β-D-glucan and ganoderic acid A. PubMed: [Determination of nine triterpenoid acids from Ganoderma lucidum of different producting areas by HPLC]. PubMed: Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin. PubMed: Pharmacokinetics of ganoderic acids a and f after oral administration of ling zhi preparation in healthy male volunteers. PubMed: Quality Difference Study of Six Varieties of Ganoderma lucidum with Different Origins. PubMed: Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of five ganoderic acids in Ganoderma lucidum and its related species. PubMed: Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. PubMed: Steroids and triterpenes from the fruit bodies of Ganoderma lucidum and their anti-complement activity. PubMed: [Simultaneous HPLC determination of four triterpenoid acids in Ganoderma lucidum]. PubMed: Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds. PubMed: Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. PubMed: Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum. PubMed: [Chemical constituents of the spores of Ganoderma lucidum]. PubMed: Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. PubMed: Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography. PubMed: Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. PubMed: New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. PubMed: Natural inhibitors for protein prenyltransferase. PubMed: [Studies on the ganoderic acid, a new constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]. PubMed: Antinociceptive components of Ganoderma lucidum.