rotundic acid
Identification
| Name | rotundic acid |
| CAS Number | 20137-37-5 |
| FDA UNII | Search |
| Molecular Formula | C30 H48 O5 |
| Molecular Weight | 488.70856000 |
| Nikkaji Number | J15.541A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.05579 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for rotundic acid usage levels up to | not for fragrance use. |
| Recommendation for rotundic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-1,10-
dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
(3beta,4alpha)-3,19,23-
trihydroxyurs-12-en-28-oic acid
urs-12-en-28-oic acid, 3,19,23-trihydroxy-, (3beta,4alpha)-
PubMed:
Identification of rotundic acid metabolites after oral administration to rats and comparison with the biotransformation by Syncephalastrum racemosum AS 3.264.
PubMed:
Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera.
PubMed:
In silico Evidence for Binding of Pentacyclic Triterpenoids to Keap1-Nrf2 Protein-Protein Binding Site.
PubMed:
Design, synthesis and evaluation of antitumor activity of new rotundic acid acylhydrazone derivatives.
PubMed:
Apoptotic Effects of Rotundic Acid on Human Esophagus and Lung Cancer Cells.
PubMed:
Chemical constituents of Eugenia catharinae and their antioxidant activity.
PubMed:
Anti-Diabetic Effects of Madecassic Acid and Rotundic Acid.
PubMed:
Triterpenes from the stem bark of Mitragyna diversifolia and their cytotoxic activity.
PubMed:
[Chemical constituents from the root of Ilex cornuta].
PubMed:
Design, synthesis and cytotoxicity of cell death mechanism of rotundic acid derivatives.
PubMed:
Novel rotundic acid derivatives: synthesis, structural characterization and in vitro antitumor activity.
PubMed:
[Non-anthraquinones constituents from the roots of Knoxia valerianoides].
PubMed:
Synthesis, characterization and cytotoxicity of new rotundic acid derivatives.
PubMed:
[Triterpenes and sterols from Nauclea latifolia].
PubMed:
Chemical constituents of the leaves of Glochidion obliquum and their bioactivity.
PubMed:
Production of triterpene acids by cell suspension cultures of Olea europaea.
PubMed:
Triterpene saponins from Randia formosa.
PubMed:
Activity of triterpenoid glycosides from the root bark of Mussaenda macrophylla against two oral pathogens.
PubMed:
Antimicrobial triterpenes from Ilex integra and the mechanism of antifungal action.
PubMed:
[Studies on constituents of Ilex chinensis Sims].