artonin E
5'-hydroxymorusin
Identification
| Name | artonin E |
| CAS Number | 129683-93-8 |
| FDA UNII | Search |
| Molecular Formula | C25 H24 O7 |
| Molecular Weight | 436.46068000 |
| Nikkaji Number | J783.477B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.02454 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for artonin E usage levels up to | not for fragrance use. |
| Recommendation for artonin E flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
4H,8H-
benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)-
5-
hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)-2-(2,4,5-trihydroxyphenyl)pyrano[2,3-h]chromen-4-one
5'-
hydroxymorusin
PubMed:
The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells.
PubMed:
Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells.
PubMed:
Artonin E and Structural Analogs from Artocarpus Species Abrogates Estrogen Receptor Signaling in Breast Cancer.
PubMed:
Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells.
PubMed:
Ultrastructural Study on the Antibacterial Activity of Artonin E versus Streptomycin against Staphylococcus aureus Strains.
PubMed:
Prenylated flavonoids and resveratrol derivatives isolated from Artocarpus communis with the ability to overcome TRAIL resistance.
PubMed:
Effects of artonin e on migration and invasion capabilities of human lung cancer cells.
PubMed:
Artonin E mediates MCL1 down-regulation and sensitizes lung cancer cells to anoikis.
PubMed:
Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae).
PubMed:
Effect of prenylated flavonoids and chalcones isolated from Artocarpus species on platelet aggregation in human whole blood.
PubMed:
Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells.
PubMed:
Four new prenylated flavonoids and xanthones from the root bark of Artocarpus nobilis.
PubMed:
New isoprenylated flavones, artochamins A--E, and cytotoxic principles from Artocarpus chama.
PubMed:
Antinephritis and radical scavenging activity of prenylflavonoids.
PubMed:
Flavonoids from Artocarpus lanceifolius.
PubMed:
Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando.
PubMed:
A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor.