artonin E

5'-hydroxymorusin

CAS: 129683-93-8 C25 H24 O7 MW: 436.46068000

Identification

Nameartonin E
CAS Number129683-93-8
FDA UNIISearch
Molecular FormulaC25 H24 O7
Molecular Weight436.46068000
Nikkaji NumberJ783.477B

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.02454 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for artonin E usage levels up tonot for fragrance use.
Recommendation for artonin E flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

artocarpus communis

Synonyms

4H,8H- benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)- 5- hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)-2-(2,4,5-trihydroxyphenyl)pyrano[2,3-h]chromen-4-one 5'- hydroxymorusin PubMed: The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells. PubMed: Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells. PubMed: Artonin E and Structural Analogs from Artocarpus Species Abrogates Estrogen Receptor Signaling in Breast Cancer. PubMed: Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells. PubMed: Ultrastructural Study on the Antibacterial Activity of Artonin E versus Streptomycin against Staphylococcus aureus Strains. PubMed: Prenylated flavonoids and resveratrol derivatives isolated from Artocarpus communis with the ability to overcome TRAIL resistance. PubMed: Effects of artonin e on migration and invasion capabilities of human lung cancer cells. PubMed: Artonin E mediates MCL1 down-regulation and sensitizes lung cancer cells to anoikis. PubMed: Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae). PubMed: Effect of prenylated flavonoids and chalcones isolated from Artocarpus species on platelet aggregation in human whole blood. PubMed: Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells. PubMed: Four new prenylated flavonoids and xanthones from the root bark of Artocarpus nobilis. PubMed: New isoprenylated flavones, artochamins A--E, and cytotoxic principles from Artocarpus chama. PubMed: Antinephritis and radical scavenging activity of prenylflavonoids. PubMed: Flavonoids from Artocarpus lanceifolius. PubMed: Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. PubMed: A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor.