ganoderic acid Me
Identification
| Name | ganoderic acid Me |
| CAS Number | 108026-93-3 |
| FDA UNII | Search |
| Molecular Formula | C34 H50 O6 |
| Molecular Weight | 554.76770000 |
| Nikkaji Number | J1.936.442I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.261e-005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ganoderic acid Me usage levels up to | not for fragrance use. |
| Recommendation for ganoderic acid Me flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
(E,6R)-6-[(3R,5R,10S,13R,14R,15S,17R)-3,15-
diacetyloxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid
PubMed:
Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi.
PubMed:
Ganoderic acid Me induces the apoptosis of competent T cells and increases the proportion of Treg cells through enhancing the expression and activation of indoleamine 2,3-dioxygenase in mouse lewis lung cancer cells.
PubMed:
Improving the fermentation production of the individual key triterpene ganoderic acid me by the medicinal fungus Ganoderma lucidum in submerged culture.
PubMed:
Ganoderic acids suppress growth and angiogenesis by modulating the NF-κB signaling pathway in breast cancer cells.
PubMed:
Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis.
PubMed:
Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum.
PubMed:
Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression.
PubMed:
Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo.