ganodermanontriol
Identification
| Name | ganodermanontriol |
| CAS Number | 106518-63-2 |
| FDA UNII | Search |
| Molecular Formula | C30 H48 O4 |
| Molecular Weight | 472.70936000 |
| MDL Number | MFCD07779162 |
| Nikkaji Number | J1.005.780I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.008667 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ganodermanontriol usage levels up to | not for fragrance use. |
| Recommendation for ganodermanontriol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
lanosta-7,9(11)-dien-3-one, 24,25,26-trihydroxy-, (24S,25R)-
(5R,10S,13R,14R,17R)-4,4,10,13,14-
pentamethyl-17-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
PubMed:
Triterpenoids from
Ganoderma lucidum
inhibit the activation of EBV antigens as telomerase inhibitors.
PubMed:
Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.
PubMed:
Effects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidum.
PubMed:
Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells.
PubMed:
In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress.
PubMed:
Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols.
PubMed:
Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA.
PubMed:
Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.
PubMed:
Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through Ã-catenin signaling.
PubMed:
Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense.
PubMed:
New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells.
PubMed:
Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.
PubMed:
Triterpene antioxidants from ganoderma lucidum.
PubMed:
Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.
PubMed:
Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease.