para-vanillic acid
4-hydroxy-3-methoxybenzoic acid
Identification
| Name | para-vanillic acid |
| IUPAC | 4-hydroxy-3-methoxybenzoic acid |
| CAS Number | 121-34-6 |
| EINECS | 204-466-8 |
| FDA UNII | GM8Q3JM2Y8 |
| Molecular Formula | C8 H8 O4 |
| Molecular Weight | 168.14856000 |
| MDL Number | MFCD00002551 |
| Nikkaji Number | J5.337F |
| Beilstein | 2208364 |
| CoE Number | 697 |
| XlogP3 | 1.40 (est) |
Regulatory
| JECFA Food Flavoring | 959 4-hydroxy-3-methoxy benzoic acid |
| DG SANTE Food Flavourings | 08.043 vanillic acid |
| FEMA Number | 3988 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 121-34-6 ; VANILLIC ACID |
Physical Properties
| Appearance | white to beige powder (est) |
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 210.00 to 213.00 °C. @ 760.00 mm Hg |
| Boiling Point | 353.43 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000020 mmHg @ 25.00 °C. |
| Flash Point | > 212.00 °F. TCC ( > 100.00 °C. ) |
| logP (o/w) | 1.430 |
| Soluble in | alcohol, 5% slightly hazy |
| Insoluble in | water |
Organoleptic Properties
| Odor Description |
at 100.00 %. Sweet creamy, phenolic, brown and powdery with vanilla beany nuances
|
| Odor sample from | Sigma-Aldrich |
| Taste Description |
creamy milky custard vanilla powdery at 30.00 ppm.
|
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | intraperitoneal-rat LD50 5020 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for para-vanillic acid usage levels up to | 0.5000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 24.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 26.00 (μg/capita/day) |
| Structure Class | I |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | 5.00000 |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | 5.00000 |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 5.00000 |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | 3.00000 |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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