zedoarondiol

CAS: 98644-24-7 C15 H24 O3 MW: 252.35388000

Identification

Namezedoarondiol
CAS Number98644-24-7
FDA UNIISearch
Molecular FormulaC15 H24 O3
Molecular Weight252.35388000
Nikkaji NumberJ589.815C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 210.9 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for zedoarondiol usage levels up tonot for fragrance use.
Recommendation for zedoarondiol flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

Curcuma zedoaria rhizome

Synonyms

(3R,3aS,8S,8aR)-3,8- dihydroxy-3,8-dimethyl-5-propan-2-ylidene-1,2,3a,4,7,8a-hexahydroazulen-6-one zedoaron diol PubMed: Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). PubMed: Zedoarondiol Inhibits Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cells Proliferation via Regulating AMP-Activated Protein Kinase Signaling Pathway. PubMed: Simultaneous determination of multiple sesquiterpenes in Curcuma wenyujin herbal medicines and related products with one single reference standard. PubMed: Intermolecular radical reaction of O,Se-acetals generated via seleno-Pummerer rearrangement. PubMed: Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb. PubMed: Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production. PubMed: Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-kappaB pathway in LPS-stimulated murine macrophages. PubMed: Sesquiterpenes from Curcuma comosa. PubMed: A new eudesmane sesquiterpene lactone from Curcuma wenyujin. PubMed: Zedoariae rhizoma and curcumin inhibits platelet-derived growth factor-induced proliferation of human hepatic myofibroblasts. PubMed: Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha. PubMed: Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury.