beta-mangostin

CAS: 20931-37-7 C25 H28 O6 MW: 424.49336000

Identification

Namebeta-mangostin
CAS Number20931-37-7
FDA UNIISearch
Molecular FormulaC25 H28 O6
Molecular Weight424.49336000
Nikkaji NumberJ15.918B

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 5.494e-005 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for beta-mangostin usage levels up tonot for fragrance use.
Recommendation for beta-mangostin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

garcinia mangostana

Synonyms

1,6- dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one PubMed: Garcixanthone A, a new cytotoxic xanthone from the pericarps of Garcinia mangostana. PubMed: Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G /G cell-cycle arrest. PubMed: Isolation and structural modifications of ananixanthone from Calophyllum teysmannii and their cytotoxic activities. PubMed: β-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways. PubMed: Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo. PubMed: Acetyl- and O-alkyl- derivatives of β-mangostin from Garcinia mangostana and their anti-inflammatory activities. PubMed: New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines. PubMed: Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana. PubMed: Depigmentation of α-melanocyte-stimulating hormone-treated melanoma cells by β-mangostin is mediated by selective autophagy. PubMed: Evidence of the gastroprotective and anti- Helicobacter pylori activities of β-mangostin isolated from Cratoxylum arborescens (vahl) blume. PubMed: Screening of mammalian DNA polymerase and topoisomerase inhibitors from Garcinia mangostana L. and analysis of human cancer cell proliferation and apoptosis. PubMed: Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa. PubMed: Metabolite footprinting of Plasmodium falciparum following exposure to Garcinia mangostana Linn. crude extract. PubMed: In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. PubMed: A new coumarin from Calophyllum hosei. PubMed: A new furanoxanthone from Garcinia mangostana. PubMed: β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivo. PubMed: A concise and efficient total synthesis of α-mangostin and β-mangostin from Garcinia mangostana. PubMed: Benzophenone and xanthone derivatives from the inflorescences of Garcinia cowa. PubMed: Apoptosis, antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f. PubMed: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). PubMed: Cytotoxic geranylated xanthones and O-alkylated derivatives of alpha-mangostin. PubMed: Anti-cancer effects of xanthones from pericarps of mangosteen. PubMed: Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line. PubMed: HPLC analysis of selected xanthones in mangosteen fruit. PubMed: Antioxidant xanthones from Cratoxylum cochinchinense. PubMed: Quantitative and qualitative determination of six xanthones in Garcinia mangostana L. by LC-PDA and LC-ESI-MS. PubMed: Xanthones from Garcinia mangostana (Guttiferae). PubMed: Cytotoxic and antimalarial prenylated xanthones from Cratoxylum cochinchinense. PubMed: Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells. PubMed: A geranylated biphenyl derivative from Garcinia malvgostana. PubMed: Antimalarial xanthones from Garcinia cowa.