diosbulbin B

CAS: 20086-06-0 C19 H20 O6 MW: 344.36360000

Identification

Namediosbulbin B
CAS Number20086-06-0
FDA UNIISearch
Molecular FormulaC19 H20 O6
Molecular Weight344.36360000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 3873 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for diosbulbin B usage levels up tonot for fragrance use.
Recommendation for diosbulbin B flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

dioscorea bulbifera

Synonyms

diosbulbin B PubMed: Development of Polyclonal Antibodies for Detection of Diosbulbin B Derived cis-Enedial Protein Adducts. PubMed: Discovery of Hepatotoxic Equivalent Combinatorial Markers from Dioscorea bulbifera tuber by Fingerprint-Toxicity Relationship Modeling. PubMed: [Chemical constituents from fresh tubers of Dioscorea bulbifera]. PubMed: Describing the holistic toxicokinetics of hepatotoxic Chinese herbal medicines by a novel integrated strategy: Dioscorea bulbifera rhizome as a case study. PubMed: Serum microRNA-122-3p, microRNA-194-5p and microRNA-5099 are potential toxicological biomarkers for the hepatotoxicity induced by Airpotato yam. PubMed: Chemical Identity of Interaction of Protein with Reactive Metabolite of Diosbulbin B In Vitro and In Vivo. PubMed: Corrigendum to "The role of Ntcp, Oatp2, Bsep and Mrp2 in liver injury induced by Dioscorea bulbifera L. and Diosbulbin B in mice" [Environ. Toxicol. Pharmacol. 51 (2017) 16-22]. PubMed: Sensitive bromine-based screening of potential toxic furanoids in Dioscorea bulbifera L. PubMed: The role of Ntcp, Oatp2, Bsep and Mrp2 in liver injury induced by Dioscorea bulbifera L. and Diosbulbin B in mice. PubMed: Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells. PubMed: Ferulic acid prevents liver injury induced by Diosbulbin B and its mechanism. PubMed: Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic. PubMed: Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism. PubMed: N-acetyl lysine/glutathione-derived pyrroles as potential ex vivo biomarkers of bioactivated furan-containing compounds. PubMed: Protection of Angelica sinensis (Oliv) Diels against hepatotoxicity induced by Dioscorea bulbifera L. and its mechanism. PubMed: Metabolism of diosbulbin B in vitro and in vivo in rats: formation of reactive metabolites and human enzymes involved. PubMed: Cytochrome p450-mediated metabolic activation of diosbulbin B. PubMed: Ferulic acid prevents liver injury and increases the anti-tumor effect of diosbulbin B in vivo. PubMed: [Protection of Grateloupia filicina polysaccharide against hepatotoxicity induced by Dioscorea bulbifera L]. PubMed: Diosbulbin B-induced liver injury in mice and its mechanism. PubMed: Gender-related pharmacokinetics and absolute bioavailability of diosbulbin B in rats determined by ultra-performance liquid chromatography-tandem mass spectrometry. PubMed: Determination of diosbulbin B in rat plasma and urine by LC-MS/MS and its application in pharmacokinetic and urinary excretion studies. PubMed: Antitumor activity of Dioscorea bulbifera L. rhizome in vivo. PubMed: [Evaluation on hepatotoxicity caused by Dioscorea bulbifera based on analysis of bile acids]. PubMed: Gender-related difference in liver injury induced by Dioscorea bulbifera L. rhizome in mice. PubMed: [Chemical constituents from tubers of Dioscorea bulbifera]. PubMed: Bitterness and toxicity in wild yam (Dioscorea spp.) tubers of Nepal. PubMed: Antitumor-promoting constituents from Dioscorea bulbifera L. in JB6 mouse epidermal cells. PubMed: Diosbulbin-B from the Leaves and Stems of Dioscorea bulbifera: 1H-1H and 13C-1H COSY NMR Studies.