oleacein
Identification
| Name | oleacein |
| CAS Number | 149183-75-5 |
| FDA UNII | Search |
| Molecular Formula | C17 H20 O6 |
| Molecular Weight | 320.34160000 |
| Nikkaji Number | J948.172I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 954.7 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for oleacein usage levels up to | not for fragrance use. |
| Recommendation for oleacein flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2-(3,4-
dihydroxyphenyl)ethyl (Z,3S)-4-formyl-3-(2-oxoethyl)hex-4-enoate
PubMed:
Quantitation of Oleuropein and Related Phenolics in Cured Spanish-Style Green, California-Style Black Ripe, and Greek-Style Natural Fermentation Olives.
PubMed:
Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils.
PubMed:
Oleacein may inhibit destabilization of carotid plaques from hypertensive patients. Impact on high mobility group protein-1.
PubMed:
Soft-MS and Computational Mapping of Oleuropein.
PubMed:
Biofortification (Se): Does it increase the content of phenolic compounds in virgin olive oil (VOO)?
PubMed:
Antimicrobial activity of Olea europaea Linné extracts and their applicability as natural food preservative agents.
PubMed:
Direct study of minor extra-virgin olive oil components without any sample modification.
H NMR multisupression experiment: A powerful tool.
PubMed:
An integrated process for the recovery of high added-value compounds from olive oil using solid support free liquid-liquid extraction and chromatography techniques.
PubMed:
Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography-tandem mass spectrometry.
PubMed:
Phenolic compounds of 'Galega Vulgar' and 'Cobrançosa' olive oils along early ripening stages.
PubMed:
Oil quality parameters and quantitative measurement of major secoiridoid derivatives in Neb Jmel olive oil from various Tunisian origins using qNMR.
PubMed:
Oleacein enhances anti-inflammatory activity of human macrophages by increasing CD163 receptor expression.
PubMed:
Quantity and quality of secoiridoids and lignans in extra virgin olive oils: the effect of two- and three-way decanters on Leccino and Raggiola olive cultivars.
PubMed:
Extraction of phenolic compounds from virgin olive oil by deep eutectic solvents (DESs).
PubMed:
Oleocanthal Modulates Estradiol-Induced Gene Expression Involving Estrogen Receptor α.
PubMed:
Quantitative Determination of Secoiridoids and Phenylpropanoids in Different Extracts of Ligustrum Vulgare L. Leaves by a Validated HPTLC-Photodensitometry Method.
PubMed:
Oleacein. translation from Mediterranean diet to potential antiatherosclerotic drug.
PubMed:
Quantitative analysis of pungent and anti-inflammatory phenolic compounds in olive oil by capillary electrophoresis.
PubMed:
Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase.
PubMed:
One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor.
PubMed:
Inhibition of human neutrophils NEP activity, CD11b/CD18 expression and elastase release by 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde, oleacein.
PubMed:
Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers.
PubMed:
Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway.
PubMed:
Direct measurement of oleocanthal and oleacein levels in olive oil by quantitative (1)H NMR. Establishment of a new index for the characterization of extra virgin olive oils.
PubMed:
Angiotensin converting enzyme (ACE) inhibitors from Jasminum azoricum and Jasminum grandiflorum.
PubMed:
Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea.