sudachitin

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4',5,7-trihydroxy-3',6,8-trimethoxyflavone

CAS: 4281-28-1 C18 H16 O8 MW: 360.31912000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namesudachitin
CAS Number4281-28-1
FDA UNIISearch
Molecular FormulaC18 H16 O8
Molecular Weight360.31912000
Nikkaji NumberJ13.496A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 56.1 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for sudachitin usage levels up tonot for fragrance use.
Recommendation for sudachitin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

chrysanthemum indicum citrus sudachi mentha piperita shoot

Synonyms

5,7- dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxychromen-4-one 4',5,7- trihydroxy-3',6,8-trimethoxyflavone PubMed: The polymethoxy flavonoid sudachitin suppresses inflammatory bone destruction by directly inhibiting osteoclastogenesis due to reduced ROS production and MAPK activation in osteoclast precursors. PubMed: Three newly identified lipophilic flavonoids in Tanacetum parthenium supercritical fluid extract penetrating the Blood-Brain Barrier. PubMed: Sudachitin, a polymethoxylated flavone, improves glucose and lipid metabolism by increasing mitochondrial biogenesis in skeletal muscle. PubMed: The multi-targeted effects of Chrysanthemum herb extract against Escherichia coli O157:H7. PubMed: Flavonoids from the Japanese monotypic genus, Nipponanthemum. PubMed: Sudachitin, a polymethoxyflavone from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. PubMed: Chrysanthemum indicum L. extract induces apoptosis through suppression of constitutive STAT3 activation in human prostate cancer DU145 cells. PubMed: Chemical constituents from the peels of Citrus sudachi. PubMed: A distinctive flavonoid chemistry for the anomalous genus Biebersteinia.