Leptosin
Identification
| Name | Leptosin |
| CAS Number | 486-23-7 |
| FDA UNII | Search |
| Molecular Formula | C22 H22 O11 |
| Molecular Weight | 462.40854000 |
| Nikkaji Number | J12.924K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 3600 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for Leptosin usage levels up to | not for fragrance use. |
| Recommendation for Leptosin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
3(2H)-
benzofuranone, 2-((3,4-dihydroxyphenyl)methylene)-6-(beta-D-glucopyranosyloxy)-7-methoxy-, (Z)-
(2Z)-2-[(3,4-
dihydroxyphenyl)methylidene]-7-methoxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-benzofuran-3-one
PubMed:
Antistaphylococcal activity and metabolite profiling of manuka honey (Leptospermum scoparium L.) after in vitro simulated digestion.
PubMed:
Sea foam as a source of fungal inoculum for the isolation of biologically active natural products.
PubMed:
Differentiation of manuka honey from kanuka honey and from jelly bush honey using HS-SPME-GC/MS and UHPLC-PDA-MS/MS.
PubMed:
New and highly potent antitumor natural products from marine-derived fungi: covering the period from 2003 to 2012.
PubMed:
General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.
PubMed:
Classification and characterization of manuka honeys based on phenolic compounds and methylglyoxal.
PubMed:
Identification of a novel glycoside, leptosin, as a chemical marker of manuka honey.
PubMed:
Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.
PubMed:
Leptosins I and J, cytotoxic substances produced by a Leptosphaeria sp. Physico-chemical properties and structures.
PubMed:
Isolation and study of the aurone glycoside leptosin from the leaves of Flemengia strobilifera.