CAS: 486-23-7 C22 H22 O11 MW: 462.40854000

Identification

NameLeptosin
CAS Number486-23-7
FDA UNIISearch
Molecular FormulaC22 H22 O11
Molecular Weight462.40854000
Nikkaji NumberJ12.924K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 3600 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for Leptosin usage levels up tonot for fragrance use.
Recommendation for Leptosin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

vaccinium oxycoccus fruit

Synonyms

3(2H)- benzofuranone, 2-((3,4-dihydroxyphenyl)methylene)-6-(beta-D-glucopyranosyloxy)-7-methoxy-, (Z)- (2Z)-2-[(3,4- dihydroxyphenyl)methylidene]-7-methoxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-benzofuran-3-one PubMed: Antistaphylococcal activity and metabolite profiling of manuka honey (Leptospermum scoparium L.) after in vitro simulated digestion. PubMed: Sea foam as a source of fungal inoculum for the isolation of biologically active natural products. PubMed: Differentiation of manuka honey from kanuka honey and from jelly bush honey using HS-SPME-GC/MS and UHPLC-PDA-MS/MS. PubMed: New and highly potent antitumor natural products from marine-derived fungi: covering the period from 2003 to 2012. PubMed: General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A. PubMed: Classification and characterization of manuka honeys based on phenolic compounds and methylglyoxal. PubMed: Identification of a novel glycoside, leptosin, as a chemical marker of manuka honey. PubMed: Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B. PubMed: Leptosins I and J, cytotoxic substances produced by a Leptosphaeria sp. Physico-chemical properties and structures. PubMed: Isolation and study of the aurone glycoside leptosin from the leaves of Flemengia strobilifera.