cirsiliol

CAS: 34334-69-5 C17 H14 O7 MW: 330.29298000

Identification

Namecirsiliol
CAS Number34334-69-5
FDA UNIISearch
Molecular FormulaC17 H14 O7
Molecular Weight330.29298000
Nikkaji NumberJ94.517J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 382.8 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for cirsiliol usage levels up tonot for fragrance use.
Recommendation for cirsiliol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

salvia officinalis

Synonyms

4H-1- benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy- 2-(3,4- dihydroxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one 6,7- dimethoxy-5,3',4'-trihydroxyflavone 3',4',5- trihydroxy-6,7-dimethoxyflavone PubMed: Bioactive flavones isolated from Tunisian Artemisia campestris L. Leaves. PubMed: Iridoid glycosides and polyphenolic compounds from Teucrium chamaedrys L. PubMed: [Studies on chemical constituents of Isodon excisoides]. PubMed: Phytochemical Analysis and Antioxidant Activity of Salvia chloroleuca Aerial Extracts. PubMed: [Chemical constituents from rhizomes of Iris germanica]. PubMed: HPLC-fingerprints and antioxidant constituents of Phyla nodiflora. PubMed: Further characterization of foliar flavonoids in Crossostephium chinense and their geographic variation. PubMed: Inhibitory effect of chemical constituents from Artemisia scoparia Waldst. et Kit. on triglyceride accumulation in 3T3-L1 cells and nitric oxide production in RAW 264.7 cells. PubMed: Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. PubMed: Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines. PubMed: [Chemical constituents of Eupatorium lindleyanum]. PubMed: Bioactivity-guided isolation of antiproliferative compounds from Centaurea jacea L. PubMed: Bis-spirolabdane diterpenoids from Leonotis nepetaefolia. PubMed: Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. PubMed: Flavones and rosmarinic acid from Salvia limbata. PubMed: Phytotoxic activity of Salvia x jamensis. PubMed: The methoxylated flavones eupatorin and cirsiliol induce CYP1 enzyme expression in MCF7 cells. PubMed: Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. PubMed: [Determination of flavonoids in buds of Herba Artemisiae Scopariae by HPLC]. PubMed: Three new compounds from Isodon melissoides. PubMed: [Studies on chemical constituents in buds of Artemisia scoparia]. PubMed: GABA(A)-receptor ligands of flavonoid structure. PubMed: Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship. PubMed: Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, Cirsiliol. PubMed: Cirsiliol and caffeic acid ethyl ester, isolated from Salvia guaranitica, are competitive ligands for the central benzodiazepine receptors. PubMed: [Resting tonus of isolated airway smooth muscles]. PubMed: Growth inhibition of human malignant glioma cells in vitro by agents which interfere with biosynthesis of eicosanoids. PubMed: Effects of cirsiliol, a flavone isolated from Achillea fragrantissima, on rat isolated ileum. PubMed: Anti-inflammatory activity and inhibition of arachidonic acid metabolism by flavonoids. PubMed: Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs. PubMed: Mechanisms of action of lipoxygenase and cytochrome P-450-mono-oxygenase inhibitors in blocking endothelium-dependent vasodilatation. PubMed: Synergistic enhancement of mitogen responses of human lymphocytes by inhibitors of cyclo-oxygenase and lipoxygenase. PubMed: Arachidonate 5-lipoxygenase inhibitors show potent antiproliferative effects on human leukemia cell lines. PubMed: Syntheses of 5,6,7- and 5,7,8-trioxygenated 3',4'-dihydroxyflavones having alkoxy groups and their inhibitory activities against arachidonate 5-lipoxygenase. PubMed: Methylated Flavones from Teucrium polium. PubMed: Potent and selective 5-lipoxygenase inhibitors: cirsiliol and AA-861. PubMed: Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells. PubMed: Arachidonate 5-lipoxygenase and its new inhibitors. PubMed: Some pharmacological, toxicological and phytochemical investigations on Centaurea phyllocephala. PubMed: Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.