glycycoumarin

CAS: 94805-82-0 C21 H20 O6 MW: 368.38560000

Identification

Nameglycycoumarin
CAS Number94805-82-0
FDA UNIISearch
Molecular FormulaC21 H20 O6
Molecular Weight368.38560000
Nikkaji NumberJ253.511D

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 4.11 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for glycycoumarin usage levels up tonot for fragrance use.
Recommendation for glycycoumarin flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Potential Uses

None Found

Natural Occurrence

glycyrrhiza glabra root

Synonyms

3-(2,4- dihydroxy-phenyl)-7-hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-2-one 3-(2,4- dihydroxyphenyl)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)chromen-2-one PubMed: Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis. PubMed: Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. PubMed: Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. PubMed: Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS. PubMed: Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase. PubMed: Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. PubMed: Pharmacokinetic Profiles of Active Components After Oral Administration of a Kampo Medicine, Shakuyakukanzoto, to Healthy Adult Japanese Volunteers. PubMed: Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy. PubMed: [Screening of active compounds with myocardial protective effects from Tongmai Yangxin pill]. PubMed: Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities. PubMed: Protective effects of glycycoumarin and procyanidin B1, active components of traditional Japanese medicine yokukansan, on amyloid β oligomer-induced neuronal death. PubMed: Metabolites identification of glycycoumarin, a major bioactive coumarin from licorice in rats. PubMed: Structures of two new flavonoids and effects of licorice phenolics on vancomycin-resistant Enterococcus species. PubMed: Simultaneous determination of five minor coumarins and flavonoids in Glycyrrhiza uralensis by solid-phase extraction and high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. PubMed: Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species. PubMed: Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice. PubMed: Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix. PubMed: Isoliquiritigenin is a novel NMDA receptor antagonist in kampo medicine yokukansan. PubMed: Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities. PubMed: Separation, characterization and dose-effect relationship of the PPARgamma-activating bio-active constituents in the Chinese herb formulation 'San-Ao decoction'. PubMed: Survey of Glycyrrhizae Radix resources in Mongolia: chemical assessment of the underground part of Glycyrrhiza uralensis and comparison with Chinese Glycyrrhizea Radix. PubMed: Two flavonoids extracts from Glycyrrhizae radix inhibit in vitro hepatitis C virus replication. PubMed: Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. PubMed: [Inhibitory effects of 11 coumarin compounds against growth of human bladder carcinoma cell line E-J in vitro]. PubMed: Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine. PubMed: Pharmaceutical evaluation of cultivated Glycyrrhiza uralensis roots in comparison of their antispasmodic activity and glycycoumarin contents with those of licorice. PubMed: Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3. PubMed: Comparative analysis of ten strains of Glycyrrhiza uralensis cultivated in Japan. PubMed: A licorice ethanolic extract with peroxisome proliferator-activated receptor-gamma ligand-binding activity affects diabetes in KK-Ay mice, abdominal obesity in diet-induced obese C57BL mice and hypertension in spontaneously hypertensive rats. PubMed: Field survey of Glycyrrhiza plants in Central Asia (1). Characterization of G. uralensis, G. glabra and the putative intermediate collected in Kazakhstan. PubMed: Antibacterial compounds of licorice against upper airway respiratory tract pathogens. PubMed: Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus. PubMed: [Phenolic constituents of licorice. IV. Correlation of phenolic constituents and licorice specimens from various sources, and inhibitory effects of licorice extracts on xanthine oxidase and monoamine oxidase]. PubMed: [Quality evaluation of Chinese licorice].