planinin
(+)-fargesin
Identification
| Name | planinin |
| CAS Number | 68296-27-5 |
| FDA UNII | Search |
| Molecular Formula | C21 H22 O6 |
| Molecular Weight | 370.40154000 |
| Nikkaji Number | J238.039K |
| XlogP3 | 2.80 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 11.89 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for planinin usage levels up to | not for fragrance use. |
| Recommendation for planinin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(+)-
fargesin
1,3-
benzodioxole, 5-(4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-, (1S-(1alpha,3aalpha,4beta,6aalpha))-
2-(3',4'-
dimethoxyphenyl)-6-(3'',4''-methylenedioxyphenyl)-3,7-dioxabicyclo(3,3,0)octane
5-[(3R,3aS,6S,6aS)-6-(3,4-
dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole
PubMed:
Antifeedant Activities of Lignans from Stem Bark of Zanthoxylum armatum DC. against Tribolium castaneum.
PubMed:
Escalation of liver malfunctioning: A step toward Herbal Awareness.
PubMed:
Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes.
PubMed:
Fargesin exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling.
PubMed:
Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS.
PubMed:
Antihypertensive effects of fargesin in vitro and in vivo via attenuating oxidative stress and promoting nitric oxide release.
PubMed:
Analysis of lignans in Magnoliae Flos by turbulent flow chromatography with online solid-phase extraction and high-performance liquid chromatography with tandem mass spectrometry.
PubMed:
A new dimeric lignan from Zanthoxylum simulans.
PubMed:
Ultrasound-Assisted Aqueous Two-Phase System for Extraction and Enrichment of Zanthoxylum armatum Lignans.
PubMed:
Fargesin as a potential βâ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.
PubMed:
A new geranylbenzofuranone from Zanthoxylum armatum.
PubMed:
New prenylated carbazole alkaloids from Zanthoxylum armatum.
PubMed:
[Study on chemical constituents of Zanthoxyli cortex's ethyl acetate extract].
PubMed:
Quantitative and structural analysis of amides and lignans in Zanthoxylum armatum by UPLC-DAD-ESI-QTOF-MS/MS.
PubMed:
Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts.
PubMed:
Intramolecular Larock indole synthesis: preparation of 3,4-fused tricyclic indoles and total synthesis of fargesine.
PubMed:
Fargesin, a component of Flos Magnoliae, stimulates glucose uptake in L6 myotubes.
PubMed:
Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice.
PubMed:
Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.
PubMed:
Antinociceptive and anti-inflammatory activities of ethyl acetate fraction from Zanthoxylum armatum in mice.
PubMed:
Liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry for the simultaneous determination of dimethoxyaschantin, dimethylliroresinol, dimethylpinoresinol, epimagnolin A, fargesin and magnolin in rat plasma.
PubMed:
Anti-Candida property of a lignan glycoside derived from Styrax japonica S. et Z. via membrane-active mechanisms.
PubMed:
Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera.
PubMed:
Suppression of inducible nitric oxide synthase expression by furfuran lignans from flower buds of Magnolia fargesii in BV-2 microglial cells.
PubMed:
Antifungal effect with apoptotic mechanism(s) of Styraxjaponoside C.
PubMed:
5-lipoxygenase-inhibitory constituents from Schizandra fructus and Magnolia flos.
PubMed:
Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells.
PubMed:
Chemistry and bioactivity of Flos Magnoliae, a Chinese herb for rhinitis and sinusitis.
PubMed:
Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells.
PubMed:
Evaluation of insecticidal activity of diterpenes and lignans from Aristolochia malmeana against Anticarsia gemmatalis.
PubMed:
Isolation and purification of lignans from Magnolia biondii Pamp by isocratic reversed-phase two-dimensional liquid chromatography following microwave-assisted extraction.
PubMed:
A new lignan glycoside from the stem bark of Styrax japonica S. et Z.
PubMed:
Allelochemicals from Stauranthus perforatus, a Rutaceous tree of the Yucatan Peninsula, Mexico.
PubMed:
C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin.
PubMed:
Determination of 1,3-benzodioxanes in Piper mullesua by high-performance thin-layer chromatography.
PubMed:
Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco.
PubMed:
A new amide from zanthoxylum armatum
PubMed:
Two new constituents from the leaves of magnolia coco
PubMed:
[Biologically active lignins from Magnolia biondii Pamp].
PubMed:
[Studies on the chemical constituents of Zanthoxylum planispinum Sieb. et Zucc].