koetjapic acid

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3,4-seco-olean-4(23),12-diene-3,30-dioic acid

CAS: 142905-27-9 C30 H46 O4 MW: 470.69342000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namekoetjapic acid
CAS Number142905-27-9
FDA UNIISearch
Molecular FormulaC30 H46 O4
Molecular Weight470.69342000
Nikkaji NumberJ1.164.835E

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.0001515 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for koetjapic acid usage levels up tonot for fragrance use.
Recommendation for koetjapic acid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

sandoricum koetjape fruit

Synonyms

(3S,4aR,6aR,7S,8S,10aR,10bS,12aS)-7-(2- carboxyethyl)-3,7,10a,10b,12a-pentamethyl-8-prop-1-en-2-yl-2,4,4a,6,6a,8,9,10,11,12-decahydro-1H-chrysene-3-carboxylic acid 3,4-seco- olean-4(23),12-diene-3,30-dioic acid PubMed: Inhibitory effect of triterpenoids from Dillenia serrata (Dilleniaceae) on prostaglandin E2 production and quantitative HPLC analysis of its koetjapic acid and betulinic acid contents. PubMed: Increased aqueous solubility and proapoptotic activity of potassium koetjapate against human colorectal cancer cells. PubMed: In vitro antimetastatic activity of koetjapic acid against breast cancer cells. PubMed: Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells. PubMed: Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe Merr. PubMed: Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense. PubMed: Koetjapic acid chloro-form hemisolvate. PubMed: Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. PubMed: Ichthyotoxic and anticarcinogenic effects of triterpenoids from Sandoricum koetjape bark. PubMed: Bioactive 12-oleanene triterpene and secotriterpene acids from Maytenus undata. PubMed: Plant anticancer agents, L. cytotoxic triterpenes from Sandoricum koetjape stems.