ganoderiol F
Identification
| Name | ganoderiol F |
| CAS Number | 114567-47-4 |
| FDA UNII | Search |
| Molecular Formula | C30 H46 O3 |
| Molecular Weight | 454.69422000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.001935 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ganoderiol F usage levels up to | not for fragrance use. |
| Recommendation for ganoderiol F flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
26,27-
dihydroxylanosta-7,9(11),24-trien-3-one
(5R,10S,13R,14R,17R)-17-[(2R)-7-
hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
PubMed:
Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.
PubMed:
Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
PubMed:
Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.
PubMed:
Anti-human immunodeficiency virus-1 protease activity of new lanostane-type triterpenoids from Ganoderma sinense.
PubMed:
Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum.
PubMed:
Anti-androgen effects of extracts and compounds from Ganoderma lucidum.
PubMed:
Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells.
PubMed:
Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.
PubMed:
Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.