crocin 2
crocetin gentiobiosylglucosyl ester
Identification
| Name | crocin 2 |
| CAS Number | 55750-84-0 |
| FDA UNII | ZF2MOD2N6Y |
| Molecular Formula | C38 H54 O19 |
| Molecular Weight | 814.83318000 |
| MDL Number | MFCD11111454 |
| Nikkaji Number | J40.299K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 346.3 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for crocin 2 usage levels up to | not for fragrance use. |
| Recommendation for crocin 2 flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
trans-
crocetin (beta-D-glucosyl)-(beta-D-gentiobiosyl) ester
all-trans-
crocetin beta-D-gentiobiosyl-beta-D-glucosyl ester
crocetin gentiobiosylglucosyl ester
crocin II
beta-D-
glucopyranose, 6-o-beta-D-glucopyranosyl-, 1-((2E,4E,6E,8E,10E,12E,14E)-beta-D-glucopyranosyl 2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate)
1-O-[(2R,3R,4S,5S,6R)-3,4,5-
trihydroxy-6-(hydroxymethyl)oxan-2-yl] 16-O-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate
PubMed:
Protective effects of saffron and its active components against oxidative stress and apoptosis in endothelial cells.
PubMed:
Effects of saffron and its constituents, crocin-1, crocin-2, and crocetin on α-synuclein fibrils.
PubMed:
The effects of crocin on the symptoms of depression in subjects with metabolic syndrome.
PubMed:
Gardenia jasminoides has therapeutic effects on LâNNAâinduced hypertension in vivo.
PubMed:
Gastrointestinal absorption, antiproliferative and anti-inflammatory effect of the major carotenoids of Gardenia jasminoides Ellis on cancer cells.
PubMed:
Two standardized fractions of Gardenia jasminoides Ellis with rapid antidepressant effects are differentially associated with BDNF up-regulation in the hippocampus.
PubMed:
[Study on crocins reference extract and application on assay of Croci Stigma].
PubMed:
Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus.
PubMed:
Quality control of Gardeniae Fructus by HPLC-PDA fingerprint coupled with chemometric methods.
PubMed:
Optimization of ultrasound-assisted extraction of gardenia fruit oil with bioactive components and their identification and quantification by HPLC-DAD/ESI-MS(2).
PubMed:
Systematic separation and purification of iridoid glycosides and crocetin derivatives from Gardenia jasminoides Ellis by high-speed counter-current chromatography.
PubMed:
Quality control and producing areas differentiation of Gardeniae Fructus for eight bioactive constituents by HPLC-DAD-ESI/MS.
PubMed:
[Study on the chemical components of Gardenia jasminoides].
PubMed:
Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.
PubMed:
[Contents of diterpenoid pigments in didifferent parts of fruit from Gardenia jasminoides].
PubMed:
[Content comparison of diterpenoid pigments in different processed products of Gardenia jasminoides].
PubMed:
[Simultaneous determination of 3 kinds of components in Gardenia by high-performance liquid chromatography under different UV-vis wave length].
PubMed:
[In vitro evaluation of the chemopreventive potential of saffron].
PubMed:
Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography.
PubMed:
Effects of crocin analogs on ocular blood flow and retinal function.