punicalin
Identification
| Name | punicalin |
| CAS Number | 65995-64-4 |
| FDA UNII | Search |
| Molecular Formula | C34 H22 O22 |
| Molecular Weight | 782.53174000 |
| Nikkaji Number | J353.470G |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 3213 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for punicalin usage levels up to | not for fragrance use. |
| Recommendation for punicalin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
D-
glucose, cyclic 4,6-(2,2'-(5,10-dihydro-2,3,7,8-tetrahydroxy-5,10-dioxo(1)benzopyrano(5,4,3-cde)(1)benzopyran-1,6-diyl)bis(3,4,5-trihydroxybenzoate)), (4(S,S))-
PubMed:
Lafoensia pacari A. St. -Hil: wound healing activity and mechanism of action of standardized hydroethanolic leaves extract.
PubMed:
On-line monitoring of Aspergillus niger GH1 growth in a bioprocess for the production of ellagic acid and ellagitannase by solid-state fermentation.
PubMed:
Impact of extraction techniques on antioxidant capacities and phytochemical composition of polyphenol-rich extracts.
PubMed:
Qualitative Analysis of Polyphenols in Macroporous Resin Pretreated Pomegranate Husk Extract by HPLC-QTOF-MS.
PubMed:
Characterisation of Pomegranate-Husk Polyphenols and Semi-Preparative Fractionation of Punicalagin.
PubMed:
Phytochemical Characterization of
Terminalia catappa
Linn. Extracts and Their antifungal Activities against
Candida
spp.
PubMed:
Multiple Activities of Punica granatum Linne against Acne Vulgaris.
PubMed:
A nematicidal tannin from Punica granatum L. rind and its physiological effect on pine wood nematode (Bursaphelenchus xylophilus).
PubMed:
Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA.
PubMed:
Punica granatum L. Hydrogel for Wound Care Treatment: From Case Study to Phytomedicine Standardization.
PubMed:
A systematic determination of polyphenols constituents and cytotoxic ability in fruit parts of pomegranates derived from five Chinese cultivars.
PubMed:
Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel.
PubMed:
Cost-effective imprinting combining macromolecular crowding and a dummy template for the fast purification of punicalagin from pomegranate husk extract.
PubMed:
The complete biodegradation pathway of ellagitannins by Aspergillus niger in solid-state fermentation.
PubMed:
Soy protein isolate does not affect ellagitannin bioavailability and urolithin formation when mixed with pomegranate juice in humans.
PubMed:
Anti-Glycation Effects of Pomegranate (Punica granatum L.) Fruit Extract and Its Components in Vivo and in Vitro.
PubMed:
Pomegranate ellagitannins stimulate growth of gut bacteria in vitro: Implications for prebiotic and metabolic effects.
PubMed:
Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions.
PubMed:
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
PubMed:
An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial.
PubMed:
Small molecule inhibitors of HCV replication from pomegranate.
PubMed:
Ellagitannin oligomers and a neolignan from pomegranate arils and their inhibitory effects on the formation of advanced glycation end products.
PubMed:
Fungal biodegradation of pomegranate ellagitannins.
PubMed:
Purification, antioxidant activity and protein-precipitating capacity of punicalin from pomegranate husk.
PubMed:
Absence of pomegranate ellagitannins in the majority of commercial Pomegranate extracts: implications for standardization and quality control.
PubMed:
Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells.
PubMed:
Environmental conditions affect the color, taste, and antioxidant capacity of 11 pomegranate accessions' fruits.
PubMed:
Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins.
PubMed:
A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer.
PubMed:
A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract.
PubMed:
Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.
PubMed:
Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV-1 reverse transcriptase.
PubMed:
Two ellagitannins from Punica granatum heartwood.
PubMed:
Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats.
PubMed:
Antioxidant and free radical scavenging effects of the tannins of Terminalia catappa L.
PubMed:
Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats.
PubMed:
Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats.
PubMed:
Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed:
Prevention of binding of rgp120 by anti-HIV active tannins.
PubMed:
Anti-AIDS agents, 2: Inhibitory effects of tannins on HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.