annonacin A

2- methyl-4-[2,8,13-trihydroxy-13-[5-(1-hydroxytridecyl)oxolan-2-yl]tridecyl]-2H-furan-5-one PubMed: Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice. PubMed: The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway. PubMed: Tucupentol, a novel mono-tetrahydrofuranic acetogenin from Annona montana, as a potent inhibitor of mitochondrial complex I. PubMed: Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. PubMed: Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe. PubMed: Annonacin, a mono-tetrahydrofuran acetogenin, arrests cancer cells at the G1 phase and causes cytotoxicity in a Bax- and caspase-3-related pathway. PubMed: Murihexol, a linear acetogenin from Annona muricata. PubMed: Cytotoxicity and antileishmanial activity of Annona muricata pericarp. PubMed: The localisations in liposomal membranes of the tetrahydrofuran ring moieties of the annonaceous acetogenins, annonacin and sylvaticin, as determined by 1H NMR spectroscopy. PubMed: Purpurediolin and purpurenin, two new cytotoxic adjacent bis-tetrahydrofuran annonaceous acetogenins from the seeds of Annona purpurea. PubMed: In vitro antitumor activities of new synthetic bistetrahydrofuran derivatives as analogs of Annonaceous acetogenins. PubMed: [Studies on the chemical constituents of Annona muricata]. PubMed: Three new adjacent bis-tetrahydrofuran acetogenins with four hydroxyl groups from Asimina triloba. PubMed: Additional bioactive acetogenins, annomutacin and (2,4-trans and cis)-10R-annonacin-A-ones, from the leaves of Annona muricata. PubMed: Muricatocins A and B, two new bioactive monotetrahydrofuran Annonaceous acetogenins from the leaves of Annona muricata. PubMed: Biologically active acetogenins from stem bark of Asimina triloba. PubMed: [Annonacins and Annonastatin from Annona squamosa]. PubMed: Annonacin, a novel, biologically active polyketide from Annona densicoma.