castalagin
vescalagin, (33beta)-
Identification
| Name | castalagin |
| CAS Number | 24312-00-3 |
| FDA UNII | BZ58QSX2MQ |
| Molecular Formula | C41 H26 O26 |
| Molecular Weight | 934.63742000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 4.227 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for castalagin usage levels up to | not for fragrance use. |
| Recommendation for castalagin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
vescalagin, (33beta)-
PubMed:
Antioxidant properties and phenolic profile characterization by LC-MS/MS of selected Tunisian pomegranate peels.
PubMed:
Molecular Interaction Between Salivary Proteins and Food Tannins.
PubMed:
Improved method for the extraction and chromatographic analysis on a fused-core column of ellagitannins found in oak-aged wine.
PubMed:
Study of the Stereochemistry and Oxidation Mechanism of Plant Polyphenols, Assisted by Computational Chemistry.
PubMed:
Polyphenol and Ellagitannin Constituents of Jabuticaba (Myrciaria cauliflora) and Chemical Variability at Different Stages of Fruit Development.
PubMed:
Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures.
PubMed:
Phytochemicals as Effective Quorum Quenchers Against Bacterial Communication.
PubMed:
Protective effect and induction of DNA repair by Myrciaria cauliflora seed extract and pedunculagin on cyclophosphamide-induced genotoxicity.
PubMed:
Chemical characterization and bioactive properties of aqueous and organic extracts of Geranium robertianum L.
PubMed:
A New Sucrase Enzyme Inhibitor from Azadirachta indica.
PubMed:
α-Glucosidase inhibition and antioxidant activity of an oenological commercial tannin. Extraction, fractionation and analysis by HPLC/ESI-MS/MS and (1)H NMR.
PubMed:
Plant-Derived Polyphenols Interact with Staphylococcal Enterotoxin A and Inhibit Toxin Activity.
PubMed:
Hydrolyzable Tannins from Sweet Chestnut Fractions Obtained by a Sustainable and Eco-friendly Industrial Process.
PubMed:
Spectroscopy analysis of phenolic and sugar patterns in a food grade chestnut tannin.
PubMed:
Valorization of solid wastes from chestnut industry processing: Extraction and optimization of polyphenols, tannins and ellagitannins and its potential for adhesives, cosmetic and pharmaceutical industry.
PubMed:
Castalagin Exerts Inhibitory Effects on Osteoclastogenesis Through Blocking a Broad Range of Signaling Pathways with Low Cytotoxicity.
PubMed:
Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex.
PubMed:
Reinvestigation of the stereochemistry of the C-glycosidic ellagitannins, vescalagin and castalagin.
PubMed:
Extracts and compounds with anti-diabetic complications and anti-cancer activity from Castanea mollissina Blume (Chinese chestnut).
PubMed:
Contribution of C-glucosidic ellagitannins to Lythrum salicaria L. influence on pro-inflammatory functions of human neutrophils.
PubMed:
Ellagitannins as synergists of ACV on the replication of ACV-resistant strains of HSV 1 and 2.
PubMed:
Tannin analysis of chestnut bark samples (Castanea sativa Mill.) by HPLC-DAD-MS.
PubMed:
Determination of C-glucosidic ellagitannins in Lythri salicariaeherba by ultra-high performance liquid chromatography coupled with charged aerosol detector: method development and validation.
PubMed:
Phenolic constituents from Alchemilla vulgaris L. and Alchemilla mollis (Buser) Rothm. at different dates of harvest.
PubMed:
Phenolic constituents from Alchemilla vulgaris L. and Alchemilla mollis (Buser) Rothm. at different dates of harvest.
PubMed:
C-glucosidic ellagitannins from Lythri herba (European Pharmacopoeia): chromatographic profile and structure determination.
PubMed:
Liquid chromatographic/electrospray ionization tandem mass spectrometric study of polyphenolic composition of four cultivars of Fragaria vesca L. berries and their comparative evaluation.
PubMed:
Three-dimensional analysis of combination effect of ellagitannins and acyclovir on herpes simplex virus types 1 and 2.
PubMed:
Phenolic compounds in chestnut (Castanea sativa Mill.) heartwood. Effect of toasting at cooperage.
PubMed:
Matrix-calibrated LC-MS/MS quantitation and sensory evaluation of oak Ellagitannins and their transformation products in red wines.
PubMed:
Development of a fractionation method for the detection and identification of oak ellagitannins in red wines.
PubMed:
Antioxidant and biological properties of bioactive phenolic compounds from Quercus suber L.
PubMed:
Castalagin from Anogeissus leiocarpus mediates the killing of Leishmania in vitro.
PubMed:
Isolation and structure of whiskey polyphenols produced by oxidation of oak wood ellagitannins.
PubMed:
Oak ellagitannins suppress the phosphorylation of the epidermal growth factor receptor in human colon carcinoma cells.
PubMed:
The use of microfluorometric method for activity-guided isolation of antiplasmodial compound from plant extracts.
PubMed:
Ellagitannin composition of blackberry as determined by HPLC-ESI-MS and MALDI-TOF-MS.
PubMed:
Anticancer and antioxidant tannins from Pimenta dioica leaves.
PubMed:
Identification and sensory evaluation of dehydro- and deoxy-ellagitannins formed upon toasting of oak wood (Quercus alba L.).
PubMed:
Main structural and stereochemical aspects of the antiherpetic activity of nonahydroxyterphenoyl-containing C-glycosidic ellagitannins.
PubMed:
Protein binding and astringent taste of a polymeric procyanidin, 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose, castalagin, and grandinin.
PubMed:
Sensory-directed identification of taste-active ellagitannins in American (Quercus alba L.) and European oak wood (Quercus robur L.) and quantitative analysis in bourbon whiskey and oak-matured red wines.
PubMed:
The chemistry of wine polyphenolic C-glycosidic ellagitannins targeting human topoisomerase II.
PubMed:
Antimicrobial activity of 10 different plant polyphenols against bacteria causing food-borne disease.
PubMed:
Conformational interpretation of vescalagin and castalagin physicochemical properties.
PubMed:
Use of DSC to detect the heterogeneity of hydrothermal stability in the polyphenol-treated collagen matrix.
PubMed:
Effect of tannins from Quercus suber and Quercus coccifera leaves on ethanol-induced gastric lesions in mice.
PubMed:
Evolution of ellagitannins in Spanish, French, and American oak woods during natural seasoning and toasting.
PubMed:
Analysis of oak tannins by liquid chromatography-electrospray ionisation mass spectrometry.
PubMed:
Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells.
PubMed:
Evolution of castalagin and vescalagin in ethanol solutions. Identification of new derivatives.
PubMed:
Evolution of phenolic compounds of spanish oak wood during natural seasoning. First results.
PubMed:
Ellagitannins and complex tannins from Quercus petraea bark.
PubMed:
Antihypertensive principles from the leaves of Melastoma candidum.
PubMed:
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
PubMed:
Study on the composition and structure of commercial chestnut tanning agent.
PubMed:
The use of tannin from chestnut (Castanea vesca).
PubMed:
Tannins occurring in the toxic Brazilian plant Thiloa glaucocarpa.
PubMed:
[On tanning compounds from the wood of chestnut and oak. IV. The structure of castalagin].