gypenoside IX
Identification
| Name | gypenoside IX |
| CAS Number | 80321-63-7 |
| FDA UNII | Search |
| Molecular Formula | C47 H80 O17 |
| Molecular Weight | 917.14100000 |
| MDL Number | MFCD28988744 |
| Nikkaji Number | J2.870.413E |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for gypenoside IX usage levels up to | not for fragrance use. |
| Recommendation for gypenoside IX flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
beta-D-
glucopyranoside, (3alpha,12beta)-3-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-xylopyranosyl-
gynosaponin I
PubMed:
Effects of gynosaponin TN-2 on L-DOPA-induced cytotoxicity in PC12 cells.
PubMed:
Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators.
PubMed:
Effect of Gynosaponin on Rumen In vitro Methanogenesis under Different Forage-Concentrate Ratios.
PubMed:
Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer.
PubMed:
Neuroprotective effects of herbal ethanol extracts from Gynostemma pentaphyllum in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
PubMed:
Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells.
PubMed:
Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway.
PubMed:
A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum.
PubMed:
Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China.
PubMed:
Protective effect of gypenosides on DNA and RNA of rat neurons in cerebral ischemia-reperfusion injury.
PubMed:
Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by CCl4 in rats.
PubMed:
Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells.
PubMed:
[Influence of gypenoside on serum lipoprotein and atherosclerosis in hyperlipidaemia animals].
PubMed:
[Inhibitory effects of gypenoside on rat heart and brain Na+, K+(-)ATPase activity].
PubMed:
[Saponins in fruits pedicels of Panax notoginseng (Burk.). F.H. Chen].