majonoside R2
Identification
| Name | majonoside R2 |
| CAS Number | 81534-63-6 |
| FDA UNII | Search |
| Molecular Formula | C41 H70 O14 |
| Molecular Weight | 786.99770000 |
| Nikkaji Number | J689.877G |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2.42 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for majonoside R2 usage levels up to | not for fragrance use. |
| Recommendation for majonoside R2 flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
(2S,3R,4S,5R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-
dihydroxy-17-[(2S,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
beta-D-
glucopyranoside, (3beta,6alpha,12beta,24S)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-beta-D-xylopyranosyl-
PubMed:
Anti-inflammatory effects of vina-ginsenoside R2 and majonoside R2 isolated from Panax vietnamensis and their metabolites in lipopolysaccharide-stimulated macrophages.
PubMed:
Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells.
PubMed:
Transcriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers.
PubMed:
Social isolation stress-induced oxidative damage in mouse brain and its modulation by majonoside-R2, a Vietnamese ginseng saponin.
PubMed:
Simultaneous determination of triterpene saponins in ginseng drugs by high-performance liquid chromatography.
PubMed:
Hepatoprotective effect of majonoside R2, the major saponin from Vietnamese ginseng (Panax vietnamensis).
PubMed:
Suppressive effects of vietnamese ginseng saponin and its major component majonoside-R2 on psychological stress-induced enhancement of lipid peroxidation in the mouse brain.
PubMed:
Saponins of plants of Panax species collected in Central Nepal, and their chemotaxonomical significance. III.
PubMed:
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
PubMed:
Bioactive saponins in vietnamese ginseng, panax vietnamensis.
PubMed:
In vitro antioxidant activity of Vietnamese ginseng saponin and its components.
PubMed:
Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I).
PubMed:
The antistress effect of majonoside-R2, a major saponin component of Vietnamese ginseng: neuronal mechanisms of action.
PubMed:
Effect of Vietnamese Ginseng on the phagocytosis in vitro and in vivo.
PubMed:
Majonoside-R2, a major constituent of Vietnamese ginseng, attenuates opioid-induced antinociception.
PubMed:
Involvement of supraspinal GABA receptors in majonoside-R2 suppression of clonidine-induced antinociception in mice.
PubMed:
Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: possible involvement of neuroactive steroids.
PubMed:
The possible involvement of GABAA systems in the antinarcotic effect of majonoside-R2, a major constituent of Vietnamese ginseng, in mice.
PubMed:
Effects of vietnamese ginseng on opioid agonist - and conditioned fear stress-induced antinociception.
PubMed:
Effects of majonoside-R2 on pentobarbital sleep and gastric lesion in psychologically stressed mice.
PubMed:
Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot-shock stress-induced antinociception in mice.
PubMed:
Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I.