majonoside R2

CAS: 81534-63-6 C41 H70 O14 MW: 786.99770000

Identification

Namemajonoside R2
CAS Number81534-63-6
FDA UNIISearch
Molecular FormulaC41 H70 O14
Molecular Weight786.99770000
Nikkaji NumberJ689.877G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 2.42 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for majonoside R2 usage levels up tonot for fragrance use.
Recommendation for majonoside R2 flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

panax japonicus

Synonyms

(2S,3R,4S,5R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12- dihydroxy-17-[(2S,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol beta-D- glucopyranoside, (3beta,6alpha,12beta,24S)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-beta-D-xylopyranosyl- PubMed: Anti-inflammatory effects of vina-ginsenoside R2 and majonoside R2 isolated from Panax vietnamensis and their metabolites in lipopolysaccharide-stimulated macrophages. PubMed: Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells. PubMed: Transcriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers. PubMed: Social isolation stress-induced oxidative damage in mouse brain and its modulation by majonoside-R2, a Vietnamese ginseng saponin. PubMed: Simultaneous determination of triterpene saponins in ginseng drugs by high-performance liquid chromatography. PubMed: Hepatoprotective effect of majonoside R2, the major saponin from Vietnamese ginseng (Panax vietnamensis). PubMed: Suppressive effects of vietnamese ginseng saponin and its major component majonoside-R2 on psychological stress-induced enhancement of lipid peroxidation in the mouse brain. PubMed: Saponins of plants of Panax species collected in Central Nepal, and their chemotaxonomical significance. III. PubMed: Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis. PubMed: Bioactive saponins in vietnamese ginseng, panax vietnamensis. PubMed: In vitro antioxidant activity of Vietnamese ginseng saponin and its components. PubMed: Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I). PubMed: The antistress effect of majonoside-R2, a major saponin component of Vietnamese ginseng: neuronal mechanisms of action. PubMed: Effect of Vietnamese Ginseng on the phagocytosis in vitro and in vivo. PubMed: Majonoside-R2, a major constituent of Vietnamese ginseng, attenuates opioid-induced antinociception. PubMed: Involvement of supraspinal GABA receptors in majonoside-R2 suppression of clonidine-induced antinociception in mice. PubMed: Majonoside-R2 reverses social isolation stress-induced decrease in pentobarbital sleep in mice: possible involvement of neuroactive steroids. PubMed: The possible involvement of GABAA systems in the antinarcotic effect of majonoside-R2, a major constituent of Vietnamese ginseng, in mice. PubMed: Effects of vietnamese ginseng on opioid agonist - and conditioned fear stress-induced antinociception. PubMed: Effects of majonoside-R2 on pentobarbital sleep and gastric lesion in psychologically stressed mice. PubMed: Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot-shock stress-induced antinociception in mice. PubMed: Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I.