allixin
Identification
| Name | allixin |
| CAS Number | 125263-70-9 |
| FDA UNII | 851A356OPF |
| Molecular Formula | C12 H18 O4 |
| Molecular Weight | 226.27226000 |
| Nikkaji Number | J627.471D |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 40.47 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for allixin usage levels up to | not for fragrance use. |
| Recommendation for allixin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
5-
hydroxy-3-methoxy-2-methyl-6-pentylpyran-4-one
3-
hydroxy-5-methoxy-6-methyl-2-pentyl-4H-pyran-4-one
4H-
pyran-4-one, 3-hydroxy-5-methoxy-6-methyl-2-pentyl-
PubMed:
Pharmacokinetic study of allixin, a phytoalexin produced by garlic
PubMed:
Chemical composition and bioactive compounds of garlic (Allium sativum L.) as affected by pre- and post-harvest conditions: A review
PubMed:
Allixin accumulation with long-term storage of garlic
PubMed:
Effect of allixin, a phytoalexin produced by garlic, on mutagenesis, DNA-binding and metabolism of aflatoxin B1
PubMed:
Allixin, a phytoalexin from garlic, inhibits the growth of Helicobacter pylori in vitro
PubMed:
Action mechanism of insulin-mimetic vanadyl-allixin complex
PubMed:
Allixin induction and accumulation by light irradiation
PubMed:
Allixin, a phytoalexin produced by garlic, and its analogues as novel exogenous substances with neurotrophic activity
PubMed:
Metallo-allixinate complexes with anti-diabetic and anti-metabolic syndrome activities
PubMed:
Antioxidant health effects of aged garlic extract
PubMed:
Molecular mechanism of antidiabetic zinc-allixin complexes: regulations of glucose utilization and lipid metabolism
PubMed:
The pharmacology of the insulinomimetic effect of zinc complexes
PubMed:
Oral administration of a zinc complex improves type 2 diabetes and metabolic syndromes
PubMed:
Bis(allixinato)oxovanadium(IV) complex is a potent antidiabetic agent: studies on structure-activity relationship for a series of hydroxypyrone-vanadium complexes
PubMed:
Structure based virtual screening of anticanerous polyphenolic phytocompounds against G-protein coupled receptor and identification of potent antagonist ligand(s) through molecular d
PubMed:
A new insulin-mimetic bis(allixinato)zinc(II) complex: structure-activity relationship of zinc(II) complexes
PubMed:
Matthew Budoff, MD: the cardiovascular effects of garlic supplementation
PubMed:
Protective effect of S-allyl-L-cysteine, a garlic compound, on amyloid beta-protein-induced cell death in nerve growth factor-differentiated PC12 cells
PubMed:
Suppression of LDL oxidation by garlic compounds is a possible mechanism of cardiovascular health benefit
PubMed:
Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein