phellopterin
7H-furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-
Identification
| Name | phellopterin |
| IUPAC | 4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one |
| CAS Number | 2543-94-4 |
| FDA UNII | Search |
| Molecular Formula | C17 H16 O5 |
| Molecular Weight | 300.31052000 |
| Nikkaji Number | J13.263B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 480.00 to 481.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 472.00 °F. TCC ( 244.40 °C. ) (est) |
| logP (o/w) | 2.867 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for phellopterin usage levels up to | not for fragrance use. |
| Recommendation for phellopterin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
7H-
furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-9-((3-methyl-2-butenyl)oxy)-
7H-
furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-
4-
methoxy-9-((3-methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one
4-
methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
4-
methoxy-9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one
4-
methoxy-9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one
PubMed:
Separation of chemical constituents from three plant medicines by counter-current chromatography using a three-phase solvent system at a novel ratio.
PubMed:
New coumarins from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi and their inhibition on NO production in LPS-activated RAW264.7 cells.
PubMed:
Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos.
PubMed:
[Chemical constituents of Angelica nitida roots].
PubMed:
Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells.
PubMed:
Chemical constituents of Cyrtomium fortumei (J.) Smith.
PubMed:
Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation.
PubMed:
[A new natural product from root of Angelica dahurica cv. Qibaizhi].
PubMed:
Biotransformation products of phellopterin by rat liver microsomes and the inhibition on NO production in LPS-activated RAW264.7 cells.
PubMed:
[Chemical constituents contained in seeds of Notopterygium franchetii].
PubMed:
Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography.
PubMed:
Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract.
PubMed:
Simultaneous determination of chromones and coumarins in Radix Saposhnikoviae by high performance liquid chromatography with diode array and tandem mass detectors.
PubMed:
Furanocoumarins from Dorstenia foetida.
PubMed:
Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms.
PubMed:
Rapid identification of furanocoumarins in Angelica dahurica using the online LC-MMR-MS and their nitric oxide inhibitory activity in RAW 264.7 cells.
PubMed:
[Chemical constituents of Incarvillea younghusbandii].
PubMed:
A new prenylated flavanonol from Seseli annuum roots showing protective effect on human lymphocytes DNA.
PubMed:
Simultaneous determination of five coumarins in Angelicae dahuricae Radix by HPLC/UV and LC-ESI-MS/MS.
PubMed:
Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS.
PubMed:
Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells.
PubMed:
[Studies on chemical constituents in roots of Heracleum rapula].
PubMed:
In vitro GABA-transaminase inhibitory compounds from the root of Angelica dahurica.
PubMed:
2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica.
PubMed:
A mixed crystal of imperatorin and phellopterin, with C--H...O, C--H...pi and pi-pi interactions.
PubMed:
Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production.
PubMed:
[Studies on chemical constituents of Peucedanum medium Dunn var. garcile Dunn ex Shan at Sheh].
PubMed:
Minor furocoumarins of Murraya koenigii.
PubMed:
Histamine-release effectors from Angelica dahurica var. dahurica root.
PubMed:
Furanocoumarins with affinity to brain benzodiazepine receptors in vitro.
PubMed:
Characterisation of the furanocoumarin phellopterin as a rat brain benzodiazepine receptor partial agonist in vitro.
PubMed:
[Chemical constituents of Notopterygium forbesii Boiss].
PubMed:
[Chemical constituents in roots of Ampelopsis sinica (Miq.) W.T. Wang].
PubMed:
Identification of eight coumarins occurring with psoralen, xanthotoxin, and bergapten on leaf surfaces.
PubMed:
[Isolation of phellopterin from the fruits of Heracleum mantegazzianum (Sommier et Levier) and Angelica archangelica L. 4. On furocoumarins].