phellopterin

7H-furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]-

CAS: 2543-94-4 C17 H16 O5 MW: 300.31052000

Identification

Namephellopterin
IUPAC4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
CAS Number2543-94-4
FDA UNIISearch
Molecular FormulaC17 H16 O5
Molecular Weight300.31052000
Nikkaji NumberJ13.263B

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 480.00 to 481.00 °C. @ 760.00 mm Hg (est)
Flash Point 472.00 °F. TCC ( 244.40 °C. ) (est)
logP (o/w) 2.867 (est)
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for phellopterin usage levels up tonot for fragrance use.
Recommendation for phellopterin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

angelica dahurica root celery leaf lemon fruit lemon fruit oil lemon oil lime fruit

Synonyms

7H- furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-9-((3-methyl-2-butenyl)oxy)- 7H- furo[3,2-g][1]benzopyran-7-one, 4-methoxy-9-[(3-methyl-2-buten-1-yl)oxy]- 4- methoxy-9-((3-methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one 4- methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one 4- methoxy-9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one 4- methoxy-9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one PubMed: Separation of chemical constituents from three plant medicines by counter-current chromatography using a three-phase solvent system at a novel ratio. PubMed: New coumarins from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi and their inhibition on NO production in LPS-activated RAW264.7 cells. PubMed: Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos. PubMed: [Chemical constituents of Angelica nitida roots]. PubMed: Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells. PubMed: Chemical constituents of Cyrtomium fortumei (J.) Smith. PubMed: Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation. PubMed: [A new natural product from root of Angelica dahurica cv. Qibaizhi]. PubMed: Biotransformation products of phellopterin by rat liver microsomes and the inhibition on NO production in LPS-activated RAW264.7 cells. PubMed: [Chemical constituents contained in seeds of Notopterygium franchetii]. PubMed: Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography. PubMed: Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract. PubMed: Simultaneous determination of chromones and coumarins in Radix Saposhnikoviae by high performance liquid chromatography with diode array and tandem mass detectors. PubMed: Furanocoumarins from Dorstenia foetida. PubMed: Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms. PubMed: Rapid identification of furanocoumarins in Angelica dahurica using the online LC-MMR-MS and their nitric oxide inhibitory activity in RAW 264.7 cells. PubMed: [Chemical constituents of Incarvillea younghusbandii]. PubMed: A new prenylated flavanonol from Seseli annuum roots showing protective effect on human lymphocytes DNA. PubMed: Simultaneous determination of five coumarins in Angelicae dahuricae Radix by HPLC/UV and LC-ESI-MS/MS. PubMed: Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS. PubMed: Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. PubMed: [Studies on chemical constituents in roots of Heracleum rapula]. PubMed: In vitro GABA-transaminase inhibitory compounds from the root of Angelica dahurica. PubMed: 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica. PubMed: A mixed crystal of imperatorin and phellopterin, with C--H...O, C--H...pi and pi-pi interactions. PubMed: Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production. PubMed: [Studies on chemical constituents of Peucedanum medium Dunn var. garcile Dunn ex Shan at Sheh]. PubMed: Minor furocoumarins of Murraya koenigii. PubMed: Histamine-release effectors from Angelica dahurica var. dahurica root. PubMed: Furanocoumarins with affinity to brain benzodiazepine receptors in vitro. PubMed: Characterisation of the furanocoumarin phellopterin as a rat brain benzodiazepine receptor partial agonist in vitro. PubMed: [Chemical constituents of Notopterygium forbesii Boiss]. PubMed: [Chemical constituents in roots of Ampelopsis sinica (Miq.) W.T. Wang]. PubMed: Identification of eight coumarins occurring with psoralen, xanthotoxin, and bergapten on leaf surfaces. PubMed: [Isolation of phellopterin from the fruits of Heracleum mantegazzianum (Sommier et Levier) and Angelica archangelica L. 4. On furocoumarins].