psi-tectorigenin

CAS: 13111-57-4 C16 H12 O6 MW: 300.26684000

Identification

Namepsi-tectorigenin
CAS Number13111-57-4
FDA UNII8HXB4THX7F
Molecular FormulaC16 H12 O6
Molecular Weight300.26684000
Nikkaji NumberJ14.262J
Beilstein0305254

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 244.3 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for psi-tectorigenin usage levels up tonot for fragrance use.
Recommendation for psi-tectorigenin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

dalbergia sissoo bark

Synonyms

5,7- dihydroxy-3-(4-hydroxyphenyl)-8-methoxy-4H-1-benzopyran-4-one 5,7- dihydroxy-3-(4-hydroxyphenyl)-8-methoxychromen-4-one iso flavone, 4',5,7-trihydroxy-8-methoxy- (7CI,8CI) iso tectorigenin 5,7,4'- trihydroxy-8-methoxyisoflavone PubMed: Belamcanda chinensis (L.) DC-An ethnopharmacological, phytochemical and pharmacological review. PubMed: Excretion of tectorigenin in rat urine orally administrated at different dosages by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. PubMed: Isolation and identification of urinary metabolites of kakkalide in rats. PubMed: Defective calcium influx in rat myelomonocytic leukemia cells which are resistant to differentiation-inducing effects of lipid A. PubMed: Multiple effects of tyrosine kinase inhibitors on vascular smooth muscle contraction. PubMed: Effect of tyrosine kinase inhibitors on luteinizing hormone-releasing hormone (LHRH)-induced gonadotropin release from the anterior pituitary. PubMed: Modulation of nucleocytosolic [Ca2+] gradient in smooth muscle by protein phosphorylation. PubMed: Calcium antagonist, TMB-8, prevents the induction of adaptive response by hydrogen peroxide or X-rays in human lymphocytes. PubMed: Signaling pathway other than phosphatidylinositol turnover is responsible for constant expression of c-myc gene in primary cultures of rat hepatocytes. PubMed: Differentiation of human monoblastic leukemia U937 cells induced by inhibitors of myosin light chain kinase and prevention of differentiation by granulocyte-macrophage colony-stimulating factor. PubMed: [Biological activity of oncogene function inhibitors isolated from microorganisms]. PubMed: Isoflavonoids, genistein, psi-tectorigenin, and orobol, increase cytoplasmic free calcium in isolated rat hepatocytes. PubMed: Inhibition of EGF-induced cytoskeletal change in A431 cells by inhibitors of phosphatidylinositol turnover. PubMed: Inhibition of epidermal growth factor-induced activation of phospholipase C by psi-tectorigenin. PubMed: [Inhibitors of growth factor functions, possible antineoplastic agents]. PubMed: Effects of inhibitors of protein tyrosine kinase activity and/or phosphatidylinositol turnover on differentiation of some human myelomonocytic leukemia cells. PubMed: Exogenous gangliosides stimulate breakdown of neuro-2A phosphoinositides in a manner unrelated to neurite outgrowth. PubMed: Inhibition of cellular phosphatidylinositol turnover by psi-tectorigenin.