(-)-alpha-cubebene

(3aS- (3aalpha,3bbeta, 4beta,7alpha,7aS*))- 3a,3b,4,5,6,7-hexahydro-3,7-dimethyl-4-(1-methyl ethyl)-1H-cyclopenta(1,3)cyclopropa(1,2)benzene

CAS: 17699-14-8 C15 H24 MW: 204.35628000 herbal

Identification

Name(-)-alpha-cubebene
CAS Number17699-14-8
FDA UNII438H9S5RG9
Molecular FormulaC15 H24
Molecular Weight204.35628000
MDL NumberMFCD00065425

Regulatory

Physical Properties

Appearance colorless clear liquid (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.88900 @ 25.00 °C.
Refractive Index 1.48200 @ 20.00 °C.
Boiling Point 245.00 to 246.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.014000 mmHg @ 25.00 °C. (est)
Flash Point > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w) 6.263 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for (-)-alpha-cubebene usage levels up tonot for fragrance use.
Recommendation for (-)-alpha-cubebene flavor usage levels up tonot for flavor use.

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Potential Uses

FR floral FR herbal waxy

Natural Occurrence

allamanda cathartica linn. flower oil brazil @ 0.10% Data angelica seed oil CO2 extract @ trace% Data anise star anise fruit anise star anise seed ayou wood oil @ 1.40% Data basil flower oil sweet @ 0.77% Data basil leaf oil sweet (ocimum basilicum) @ 0.66% Data basil oil basil shoot oil bay laurel leaf bay leaf oil @ 0.00-<0.01% Data cascarilla bark oil @ 0.04% Data cedrela wood oil @ 8.00% Data chamomile garden chamomile plant chamomile oil morocco @ 0.30% Data chamomile sweet false chamomile plant clary sage oil france @ trace% Data clary sage oil spain @ 0.36% Data clove bud oil @ 0.66% Data clove fruit clove leaf clove leaf oil @ 0.08% Data clove stem oil india @ 0.49% Data croton cajucara benth. leaf oil brazil @ trace% Data croton flavens l. (welensali) leaf oil curacao @ 0.20% Data cubeb oil @ 1.65% Data curry wood leaf oil australia @ 0.20% Data cypress oil @ 0.07-0.15% Data dill shoot dill weed oil cuba @ trace% Data eucalyptus globulus bud oil @ 0.27% Data eucalyptus globulus fruit oil @ 0.34% Data eucalyptus globulus oil @ 0.25% Data eucalyptus globulus oil rwanda @ 0.03% Data galangal root oil @ 0.04% Data geranium petiole oil india @ 0.10% Data geranium rose-scented oil (pelargonium spp.) cuba @ 0.10% Data geranium stem oil india @ 0.29% Data ginger rhizome oil guava fruit oil reunion @ 0.10% Data hyptis suaveolens (l.) poit. oil mali @ trace-0.10% Data juniper berry oil @ 0.90% Data juniper branch oil @ 0.50% Data labdanum oil @ 0.30% Data lemon balm shoot lemon oil lime oil expressed florida @ trace% Data mandarin fruit mandarin oil italy @ trace% Data manuka var. scoparium oil new zealand @ 3.95% Data marsypianthes chamaedrys (vahl) kuntze oil brazil @ 0.20% Data melissa oil slovak republic @ 0.26% Data mikania cordata (burm. f.) b.l. robinson var. cordata leaf oil france @ 0.10% Data nutmeg oil orange fruit orange peel oil bitter china @ trace% Data oregano shoot parsley leaf pepper black pepper fruit oil pepper oil black india @ 0.10% Data pepper tree berry oil @ 0.13% Data pepper tree leaf oil @ 0.01% Data peppermint oil CO2 extract @ trace% Data phlomis fruticosa l. flower oil greece @ 1.90% Data phoebe oil brazil @ 0.42% Data pine needle oil dwarf @ 0.33% Data piper cernum vell. var. cernum yuncker leaf oil brazil @ 0.30% Data polyalthia australis (benth.) jessup leaf oil australia @ 0.30% Data ravintsara leaf oil @ 0.47%% Data rosemary oil CO2 extract @ 0.43% Data sage oil spain @ 0.0-0.2% Data salvia lavandulifolia vahl. leaf oil @ 0.10% Data salvia plebeia oil @ 2.88% Data salvia sclarea seed oil tunisia @ 2.86% Data santolina oil @ 0.66% Data sugandha kokila berry oil @ 0.70% Data sundacarpus amarus (blume) c.n. page leaf oil australia @ trace% Data tea tree oil australia @ 0.09% Data wormwood oil annus vietnam @ 0.97% Data zanthoxylum nitidum l. leaf oil australia @ 0.70% Data

Synonyms

a- cubebene alpha- cubebene (3aS- (3aalpha,3bbeta, 4beta,7alpha,7aS*))- 3a,3b,4,5,6,7- hexahydro-3,7-dimethyl-4-(1-methyl ethyl)-1H-cyclopenta(1,3)cyclopropa(1,2)benzene PubMed: Chemical composition of the essential oil of Lepidagathis fasciculata from Bondla forest of Goa, India. PubMed: Chemical diversity of volatiles of Teucrium orientale L. var. orientale, var. puberulens, and var. glabrescens determined by simultaneous GC-FID and GC/MS techniques. PubMed: Volatile constituents of Origanum vulgare L., 'thymol' chemotype: variability in North India during plant ontogeny. PubMed: Essential oil polymorphism of wild growing Hungarian thyme (Thymus pannonicus) populations in the Carpathian Basin. PubMed: Inhibitor and substrate activities of sesquiterpene olefins toward +-δ-cadinene-8-hydroxylase, a cytochrome P450 monooxygenase (CYP706B1). PubMed: Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem. PubMed: Volatile constituents of Ocimum minimum herb cultivated in Portugal. PubMed: Essential oil composition from two species of Piperaceae family grown in Colombia. PubMed: Identification of a novel compound that stimulates intracellular calcium increase and CXCL8 production in human neutrophils from Schisandra chinensis. PubMed: Composition of semivolatile compounds of 10 Cinnamomum species from China and Myanmar. PubMed: Development of a host-based semiochemical lure for trapping emerald ash borer Agrilus planipennis (Coleoptera: Buprestidae). PubMed: Platinum- and gold-catalyzed rearrangement reactions of propargyl acetates: total syntheses of (-)-alpha-cubebene, (-)-cubebol, sesquicarene and related terpenes. PubMed: Volatile constituents of redblush grapefruit (Citrus paradisi) and pummelo (Citrus grandis) peel essential oils from Kenya. PubMed: The pathogen causing Dutch elm disease makes host trees attract insect vectors. PubMed: Anxiolytic-like actions of the hexane extract from leaves of Annona cherimolia in two anxiety paradigms: possible involvement of the GABA/benzodiazepine receptor complex. PubMed: Electroantennography in the study of two stingless bee species (Hymenoptera: Meliponini). PubMed: Volatile constituents of the flower and fruit oils of Pittosporum tobira (Thunb.) Ait. grown in Iran. PubMed: Volatile oil composition of the aerial parts of Ajuga orientalis L. from Iran. PubMed: The propolis of stingless bees: terpenes from the tibia of three Frieseomelitta species. PubMed: epi-Cubebanes from Solidago canadensis. PubMed: A four-component attractant for the mexican fruit fly,Anastrepha ludens (Diptera: Tephritidae), from host fruit. PubMed: Components of moribund American elm trees as attractants to elm bark beetles,Hylurgopinus rufipes andScolytus multistriatus. PubMed: Effects of multilure components on twig-crotch feeding by European elm bark beetles. PubMed: Field response of the dutch elm disease vectors,Scolytus multistriatus (Marsham) andS. scolytus (F.) (Coleoptera: Scolytidae) to 4-methyl-3-heptanol baits containing α-, β-,δ-, or δ-multistriatin. PubMed: Response ofScolytus multistriatus (Coleoptera: Scolytidae) to α- and δ-multistriatin in Switzerland.