bavachinin

4'-hydroxy-7-methoxy-6-prenylflavanone

CAS: 19879-30-2 C21 H22 O4 MW: 338.40314000

Identification

Namebavachinin
IUPAC2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
CAS Number19879-30-2
FDA UNIIVL3EV483SZ
Molecular FormulaC21 H22 O4
Molecular Weight338.40314000
MDL NumberMFCD06858307
Beilstein3629340

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 537.12 °C. @ 760.00 mm Hg (est)
Flash Point 375.00 °F. TCC ( 190.30 °C. ) (est)
logP (o/w) 3.946 (est)
Soluble in water, 0.945 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD > 1000 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for bavachinin usage levels up tonot for fragrance use.
Recommendation for bavachinin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

psoralea corilifolia seed

Synonyms

bavachinin A 4H-1- benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)- flavanone, 4'-hydroxy-7-methoxy-6-(3-methyl-2-butenyl)- (8CI) 4'- hydroxy-7-methoxy-6-(3-methyl-2-butenyl) flavanone 4'- hydroxy-7-methoxy-6-(3-methyl-2-butenyl)flavanone 4'- hydroxy-7-methoxy-6-prenylflavanone 2-(4- hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one 2-(4- hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one 2-(4- hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydro-4H-chromen-4-one 2-(4- hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one 7-ortho- methyl bavachin PubMed: Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents. PubMed: Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. PubMed: [Constituent of natural food additive hokosshi extract and an analytical method for the additive in foods]. PubMed: Antioxidative components of Psoralea corylifolia (Leguminosae). PubMed: Antiinflamatory, antipyretic & analgesic properties of bavachinin-a flavanone isolated from seeds of Psoralea corylifolia Linn. (Babchi). PubMed: Screening of neuraminidase inhibitors from traditional Chinese medicines by integrating capillary electrophoresis with immobilized enzyme microreactor. PubMed: Effect of Bavachinin and its derivatives on T cell differentiation. PubMed: [Chemical constituents from Psoralea corylifolia and their antioxidant alpha-glucosidase inhibitory and antimicrobial activities]. PubMed: Treatment of allergic inflammation and hyperresponsiveness by a simple compound, Bavachinin, isolated from Chinese herbs. PubMed: Biotransformation of bavachinin by three fungal cell cultures. PubMed: Isobavachalcone and bavachinin from Psoraleae Fructus modulate Aβ42 aggregation process through different mechanisms in vitro. PubMed: Psoralea corylifolia L. (Buguchi) - folklore to modern evidence: review. PubMed: Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. PubMed: Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs. PubMed: Anti-angiogenic and anti-tumor activity of Bavachinin by targeting hypoxia-inducible factor-1α. PubMed: Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. PubMed: Development of a fully automated on-line solid phase extraction and high-performance liquid chromatography with diode array detection method for the pharmacokinetic evaluation of bavachinin: a study on absolute bioavailability and dose proportionality. PubMed: Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. PubMed: Bioactive constituents from Chinese natural medicines. XXXIII. Inhibitors from the seeds of Psoralea corylifolia on production of nitric oxide in lipopolysaccharide-activated macrophages. PubMed: In vitro BACE-1 inhibitory phenolic components from the seeds of Psoralea corylifolia. PubMed: Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography. PubMed: Antioxidative components of Psoralea corylifolia (Leguminosae). PubMed: Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines.