vinpocetine
eburnamenine-14-carboxylic acid, ethyl ester, (3a,16a)-
Identification
| Name | vinpocetine |
| CAS Number | 42971-09-5 |
| EINECS | 256-028-0 |
| FDA UNII | 543512OBTC |
| Molecular Formula | C22 H26 N2 O2 |
| Molecular Weight | 350.46162000 |
| Nikkaji Number | J3.510F |
| Beilstein | 0900803 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 419.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 406.00 °F. TCC ( 207.50 °C. ) (est) |
| logP (o/w) | 5.137 (est) |
| Soluble in | water, 5.924 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 117 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | special dietary and nutritional additives |
| Recommendation for vinpocetine usage levels up to | not for fragrance use. |
| Recommendation for vinpocetine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
apovincaminic acid ethyl ester
(+)-
apovincaminic acid ethyl ester
(+)-cis-
apovincaminic acid ethyl ester
3-a,16-a-
apovincaminic acid ethyl ester
3a,16a-
apovincaminic acid ethyl ester
cis-
apovincaminic acid ethyl ester
(3S,16S)-
apovincaminic acid ethylester
bravinton
ceractin
(3a,16a)-
eburnamenine-14-carboxylic acid ethyl ester
eburnamenine-14-carboxylic acid, ethyl ester, (3a,16a)-
ethyl (+)-apovincaminate
ethyl (+)-cis-apovincaminate
ethyl (3a,16a)-eburnamenine-14-carboxylate
(11aS,11bS)-11a-
ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester
vinpocetine 98% min.
vinpocetine 99.5% min.
vinpocetinum
PubMed:
Identification and quantification of vinpocetine and picamilon in dietary supplements sold in the United States.
PubMed:
Omeprazole does not change the oral bioavailability or pharmacokinetics of vinpocetine in rats.
PubMed:
Preventive effect of piracetam and vinpocetine on hypoxia-reoxygenation induced injury in primary hippocampal culture.
PubMed:
Comparison of self-microemulsifying drug delivery system versus solid dispersion technology used in the improvement of dissolution rate and bioavailability of vinpocetine.
PubMed:
Herbal medicine in the treatment of Alzheimer's disease.
PubMed:
Bioavailability of vinpocetine and interference of the time of application with food intake.