laevo-valine
L-valine
Identification
| Name | laevo-valine |
| IUPAC | (2S)-2-amino-3-methylbutanoic acid |
| CAS Number | 72-18-4 |
| EINECS | 200-773-6 |
| FDA UNII | HG18B9YRS7 |
| Molecular Formula | C5 H11 N O2 |
| Molecular Weight | 117.14807000 |
| MDL Number | MFCD00064220 |
| Nikkaji Number | J9.179K |
| Beilstein | 1721136 |
| XlogP3 | -2.30 (est) |
Regulatory
| DG SANTE Food Flavourings | 17.028 L-valine |
| FEMA Number | 3444 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 72-18-4 ; L-VALINE |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | white crystals (est) |
| Assay | 96.00 to 100.00 |
| Food Chemicals Codex Listed | Yes |
| Melting Point | 300.00 to 315.00 °C. @ 760.00 mm Hg |
| Boiling Point | 213.64 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.063000 mmHg @ 25.00 °C. (est) |
| Flash Point | 181.00 °F. TCC ( 83.00 °C. ) (est) |
| logP (o/w) | 0.289 (est) |
| Soluble in | water, 7.446e+004 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antistatic agents |
Organoleptic Properties
| Odor Strength | none |
| Odor Description | at 100.00 %. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | intraperitoneal-rat LD50 5390 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | special dietary and nutritional additives |
| Recommendation for laevo-valine usage levels up to | not for fragrance use. |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Charkit Chemical Corporation
The Specialty Chemical Specialists
Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
Jiangyin Healthway International Trade Co., Ltd
Independent Ingredients Supplier
We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Sigma-Aldrich
Complete Supply Chain
The perfect blend of products and services that bring your creativity to life.
Qingdao Free Trade Zone United International Co Ltd
Quality Products
A partner in your supply chain solution.
Potential Uses
Natural Occurrence
Synonyms
ajipure valine
2-
amino-3-methyl butanoic acid
2-
amino-3-methyl butyric acid
(2S)-2-
amino-3-methylbutanoic acid
(S)-2-
amino-3-methylbutanoic acid
L-2-
amino-3-methylbutanoic acid
(S)-(+)-2-
amino-3-methylbutyric acid
(S)-2-
amino-3-methylbutyric acid
L-2-
amino-3-methylbutyric acid
(S)-alpha-
amino-beta-methyl butyric acid
laevo-alpha-
amino-beta-methyl butyric acid
L-alpha-
amino-beta-methylbutyric acid
(S)-a-
aminoisovaleric acid
L-(+)-a-
aminoisovaleric acid
L-(+)-alpha-
aminoisovaleric acid
L-2-
aminoisovaleric acid
laevo(+)-alpha-
aminoisovaleric acid
valine
(S)-
valine
(S)-(+)-
valine
L-
valine
L-(+)-
valine
L-
valine FCC
L-
valine FCC; USP
L-
valine USP
valine, L-
PubMed:
Salting-In with a Salting-Out Agent: Explaining the Cation Specific Effects on the Aqueous Solubility of Amino Acids.
PubMed:
Spectroscopic studies of amino Acid ionic liquid-supported schiff bases.
PubMed:
Development of analytical methods for the determination of tenuazonic acid analogues in food commodities.
PubMed:
Reduction of the off-flavor volatile generated by the yogurt starter culture including Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus in soymilk.
PubMed:
Molecular and sensory characterization of gamma-glutamyl peptides as key contributors to the kokumi taste of edible beans (Phaseolus vulgaris L.).
PubMed:
Conversion of L-leucine to isovaleric acid by Propionibacterium freudenreichii TL 34 and ITGP23.
PubMed:
ZnCl2-mediated practical protocol for the synthesis of Amadori ketoses.
PubMed:
Reduction of the off-flavor volatile generated by the yogurt starter culture including Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus in soymilk.
PubMed:
Hydrolysis of wheat gluten by combining peptidases of Flammulina velutipes and electrodialysis.
PubMed:
Structures and reactions of compounds involved in pink discolouration of onion.
PubMed:
Purification and structure analysis of mycolic acids in Corynebacterium glutamicum.
PubMed:
Structural analysis of a new cytotoxic demethylated analogue of neo-N-methylsansalvamide with a different peptide sequence produced by Fusarium solani isolated from potato.
PubMed:
Leucine is essential for attenuating fetal growth restriction caused by a protein-restricted diet in rats.
PubMed:
Effects of ¹â´C-labelled precursor feeding on production of beauvericin, enniatins H, I, and MK1688 by Fusarium oxysporum KFCC11363P.
PubMed:
Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis.
PubMed:
Spore germination of the psychrotolerant, red meat spoiler, Clostridium frigidicarnis.
PubMed:
Origin and Incidence of 2-Methoxy-3,5-dimethylpyrazine, a Compound with a "Fungal" and "Corky" Aroma Found in Cork Stoppers and Oak Chips in Contact with Wines.
PubMed:
Gellan gum as an immobilization matrix for the production of cyclosporin A.
PubMed:
Global regulation of food supply by Pseudomonas putida DOT-T1E.
PubMed:
Statistical optimization for improved production of cyclosporin a in solid-state fermentation.
PubMed:
Construction of a novel shuttle vector for use in Brevibacterium flavum, an industrial amino acid producer.
PubMed:
Heating improves poor compliance with branched chain amino acid-rich supplementation in patients with liver cirrhosis: A before-after pilot study.
PubMed:
Olfactory conditioning in the zebrafish (Danio rerio).
PubMed:
Liquid chromatography-tandem mass spectrometry characterization of ergocristam degradation products.
PubMed:
Clostridium perfringens spore germination: characterization of germinants and their receptors.
PubMed:
Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions.
PubMed:
Amino acid and carbohydrate preferences in C57BL/6ByJ and 129P3/J mice.
PubMed:
Molecular and sensory characterization of gamma-glutamyl peptides as key contributors to the kokumi taste of edible beans (Phaseolus vulgaris L.).
PubMed:
Identification of two novel pigment precursors and a reddish-purple pigment involved in the blue-green discoloration of onion and garlic.
PubMed:
Sequence diversity of the peptaibol antibiotic suzukacillin-A from the mold Trichoderma viride.
PubMed:
Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study).
PubMed:
Atmospheric oxygen and other conditions affecting the production of cereulide by Bacillus cereus in food.
PubMed:
Suppression of the bitterness of enteral nutrients using increased particle sizes of branched-chain amino acids (BCAAs) and various flavours: a taste sensor study.
PubMed:
5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.
PubMed:
A sensitive gas chromatographic-tandem mass spectrometric method for detection of alkylating agents in water: application to acrylamide in drinking water, coffee and snuff.
PubMed:
Industrial production of amino acids by coryneform bacteria.
PubMed:
Design of chiral monochloro-s-triazine reagents for the liquid chromatographic separation of amino acid enantiomers.
PubMed:
Biosynthesis of strawberry aroma compounds through amino acid metabolism.
PubMed:
Stereodifferentiation of 3-hydroxyisobutyric- and 3-aminoisobutyric acid in human urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry.
PubMed:
Olfactory discrimination of amino acids in brown bullhead catfish.
PubMed:
Response of rainbow trout (Oncorhynchus mykiss) to supplements of individual essential amino acids in a semipurified diet, including an estimate of the maintenance requirement for essential amino acids.
PubMed:
Muscle and liver protein synthesis adapt efficiently to food deprivation and refeeding in 12-month-old rats.
PubMed:
Determination of D-malic acid in apple juice by liquid chromatography: collaborative study.
PubMed:
The significance of apical K+ channels in mudpuppy feeding behavior.
PubMed:
Nutritional profile and antimicrobial spectrum of the spice Aframomum danielli K. Schum.
PubMed:
Isoleucine requirements of the chicken: the effect of excess leucine and valine on the response to isoleucine.
PubMed:
L-tyrosine potentiates the anorexia induced by mixed-acting sympathomimetic drugs in hyperphagic rats.
PubMed:
Performance and nutrient balance in growing swine fed low-protein diets supplemented with amino acids and potassium.
PubMed:
Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats.
PubMed:
Comparative effects of individual amino acid excesses when added to a corn-soybean meal diet: effects on growth and dietary choice in the chick.
PubMed:
Order of binding of substrate to valyl-tRNA synthetase from Bacillus stearothermophilus in amino acid activation reaction.
PubMed:
Effect of nutritional method on adaptation of the intestinal remnant after massive bowel resection.
PubMed:
Effect of food intake on intestinal absorption and mucosal hydrolases in alloxan diabetic rats.