2-methoxy-4-vinyl phenol

2-methoxy-4-vinylphenol

CAS: 7786-61-0 C9 H10 O2 MW: 150.17710000 spicy spicy

Identification

Name2-methoxy-4-vinyl phenol
IUPAC4-ethenyl-2-methoxyphenol
CAS Number7786-61-0
EINECS232-101-2
FDA UNIIDA069CTH0O
Molecular FormulaC9 H10 O2
Molecular Weight150.17710000
MDL NumberMFCD00015437
Nikkaji NumberJ134.783G
Beilstein2044521
CoE Number177
XlogP32.40 (est)

Regulatory

JECFA Food Flavoring725 2-methoxy-4-vinylphenol
DG SANTE Food Flavourings04.009 2-methoxy-4-vinylphenol
FEMA Number2675
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)7786-61-0 ; 2-METHOXY-4-VINYLPHENOL
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to yellow clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.10500 to 1.11500 @ 25.00 °C., 1.10500 to 1.11500 @ 20.00 °C.
Pounds per Gallon - (est). 9.195 to 9.278
Pounds per Gallon - est. 9.205 to 9.289
Refractive Index 1.57000 to 1.58000 @ 20.00 °C., 1.57000 to 1.58400 @ 20.00 °C.
Melting Point 25.00 to 29.00 °C. @ 760.00 mm Hg
Boiling Point 224.00 °C. @ 760.00 mm Hg, 100.00 °C. @ 5.00 mm Hg
Vapor Pressure 0.019000 mmHg @ 25.00 °C. (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 2.573 (est)
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength high ,
Substantivity 240 hour(s) at 100.00 %
Odor Description
at 0.10 % in dipropylene glycol.
Sweet, spicy, clove-like, somewhat smoky
Odor sample from FRUTAROM USA INC,
Taste Description
spicy powdery clove phenolic woody smoky balsamic amber
sweet
Clove, Smoky, Balsamic, Vanilla

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for 2-methoxy-4-vinyl phenol usage levels up to0.0500 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)2.60 (μg/capita/day)
baked goods20.00000
beverages(nonalcoholic)2.00000
beverages(alcoholic)20.00000
breakfast cereal-
cheese-
chewing gum2.00000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy4.00000
fruit ices-
gelatins / puddings4.00000
granulated sugar-
gravies3.00000
hard candy1.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products3.00000
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy8.00000
soups-
sugar substitutes-
sweet sauces-

ACS International GmbH

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Advanced Biotech. Inc.

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Augustus Oils Ltd

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View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Axxence Aromatic GmbH

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Foreverest Resources Ltd.

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FRUTAROM USA INC,

Flavor & Specialty Ingredients

Your preferred partner for flavour and fragrance success.

View All Website +44 (0) 1429 863 222 Sales.IFFIngredients@iff.com

Lluch Essence S.L.

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M&U International LLC

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Natural Advantage

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Penta International Corporation

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Riverside Aromatics Ltd.

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Robinson Brothers Limited

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Award-winning UK chemical manufacturer of chemical intermediates and high-impact aroma chemicals.

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Sigma-Aldrich

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Symrise AG

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Synerzine, Inc.

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Tianjin Danjun International Trade Co., LTD.

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R C Treatt and Co Ltd

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Potential Uses

FR apple FR chocolate FR coffee FR oriental FR patchouli FR peanut FR peanut FL rum FR saffron FL smoke FR spice FR spice FR strawberry FL tea FR tobacco FL tomato topnotes FR vanilla FR vetiver FL whiskey FR woody

Natural Occurrence

apple fruit PMC asparagus shoot beer PMC carrot seed cider PMC coffee PMC corn husk oil corn seed kohlrabi stem oat seed orange fruit juice parsley leaf oil @ 0.42% Data peanut roasted peanut raspberry red raspberry fruit rice cakes PbMd PMC rum PMC sesame fruit sesame seed spearmint shoot strawberry wild strawberry fruit tea tobacco burley tomato leaf tomato seed vanilla PMC whiskey PMC wine PMC

Synonyms

4- ethenyl-2-methoxyphenol guaiacol, 4-vinyl- 2- hydroxy-3-methoxystyrene 4- hydroxy-3-methoxystyrene 4- hydroxy-3-methoxyvinyl benzene 4- hydroxy-3-methoxyvinylbenzene 2- methoxy-4-ethenylphenol 3- methoxy-4-hydroxystyrene 2- methoxy-4-vinyl phenol 2- methoxy-4-vinylphenol o- methoxy-p-vinylphenol phenol, 2-methoxy-4-vinyl- phenol, 4-ethenyl-2-methoxy- phenol, 4-vinyl-2-methoxy- varamol (IFF) varamol-106 (IFF) p- vinyl catechol-o-methyl ether para- vinyl catechol-ortho-methyl ether 4- vinyl guaiacol p- vinyl guaiacol para- vinyl guaiacol 4- vinyl guaiacol natural 1% in ethyl acetate 4- vinyl guaiacol natural 1% in ethyl alcohol 4- vinyl guaiacol natural 1% in P.G. 4- vinyl guaiacol natural 5% in ethyl acetate 4- vinyl guaiacol natural 5% in ethyl alcohol 4- vinyl guaiacol natural 5% in P.G. 4- vinyl-2-methoxy-phenol 4- vinyl-2-methoxyphenol 4- vinyl-guaiacol p- vinylcatechol-o-methyl ether vinylcatechol-O-methyl ether, p- 4- vinylguaiacol p- vinylguaiacol para- vinylguaiacol 4- vinylguaiacol 10% in PG. 4- vinylguaiacol in 10% P.G. vinylguaiacol natural 10% in triacetin 4- vinylguaiacol pure PubMed: Characterization of the key aroma compounds in two bavarian wheat beers by means of the sensomics approach. PubMed: Evaluation of aroma differences between high-salt liquid-state fermentation and low-salt solid-state fermentation soy sauces from China. PubMed: [Chemical consitituents from root of Isatis indigotica]. PubMed: Key aroma compounds in roasted in-shell peanuts. PubMed: Chemical characterization and acaricide potential of essential oil from aerial parts of Tagetes patula L. (Asteraceae) against engorged adult females of Rhipicephalus sanguineus (Latreille, 1806). PubMed: Characterization of the aroma signature of styrian pumpkin seed oil ( Cucurbita pepo subsp. pepo var. Styriaca) by molecular sensory science. PubMed: Identification of aroma active compounds of cereal coffee brew and its roasted ingredients. PubMed: Bioprocess design for the microbial production of natural phenolic compounds by Debaryomyces hansenii. PubMed: Production of vinyl derivatives from alkaline hydrolysates of corn cobs by recombinant Escherichia coli containing the phenolic acid decarboxylase from Lactobacillus plantarum CECT 748T. PubMed: Characterization of the key aroma compounds in rape honey by means of the molecular sensory science concept. PubMed: Anti-inflammatory effect of 2-methoxy-4-vinylphenol via the suppression of NF-κB and MAPK activation, and acetylation of histone H3. PubMed: Decarboxylation of ferulic acid to 4-vinyl guaiacol by Streptomyces setonii. PubMed: Analysis of essential oils from Scutellaria orientalis ssp. alpina and S. utriculata by GC and GC-MS. PubMed: Efficient synthesis of hydroxystyrenes via biocatalytic decarboxylation/deacetylation of substituted cinnamic acids by newly isolated Pantoea agglomerans strains. PubMed: Characterization of odor-active compounds of various cherry wines by gas chromatography-mass spectrometry, gas chromatography-olfactometry and their correlation with sensory attributes. PubMed: Characteristics of lignin from flax shives as affected by extraction conditions. PubMed: Cloning, sequencing, and overexpression in Escherichia coli of the Enterobacter sp. Px6-4 gene for ferulic acid decarboxylase. PubMed: Chemical composition and antimicrobial activity of volatiles from Degenia velebitica, a European stenoendemic plant of the Brassicaceae family. PubMed: 2-Methoxy-4-vinylphenol can induce cell cycle arrest by blocking the hyper-phosphorylation of retinoblastoma protein in benzo[a]pyrene-treated NIH3T3 cells. PubMed: Changes in volatile aroma compounds of organic fragrant rice during storage under different conditions. PubMed: Volatile compounds and the changes in their concentration levels during storage in beers containing varying malt concentrations. PubMed: Identification of novel aroma-active thiols in pan-roasted white sesame seeds. PubMed: Volatile constituents of the aerial parts of white salsify (Tragopogon porrifolius L., Asteraceae). PubMed: Bioproduction of lauryl lactone and 4-vinyl guaiacol as value-added chemicals in two-phase biotransformation systems. PubMed: Analysis of essential oil from Teucrium maghrebinum Greuter et Burdet growing wild in Algeria. PubMed: Pharmacological activity of compounds extracted from persimmon peel (Diospyros kaki THUNB.). PubMed: Free and hydrolytically released volatile compounds of Vitis vinifera L. cv. Fiano grapes as odour-active constituents of Fiano wine. PubMed: [Insecticidal activity and active components of alcohol extract from Juglans mandshurica Maxim leaves]. PubMed: Formation of 4-vinyl guaiacol as an intermediate in bioconversion of ferulic acid by Schizophyllum commune. PubMed: A structure-activity relationship study on a natural germination inhibitor, 2-methoxy-4-vinylphenol (MVP), in wheat seeds to evaluate its mode of action. PubMed: Changes in key odorants of raw coffee beans during storage under defined conditions. PubMed: [Extraction and determination of essential oils in Indocalamus latifolius leaves and Indocalamus tessellatus leaves]. PubMed: Comparison of three lychee cultivar odor profiles using gas chromatography-olfactometry and gas chromatography-sulfur detection. PubMed: [Studies on the chemical constituents of the essential oil from the leaves of Dalbergia odorifera T. Chen]. PubMed: [Contrastive analysis of volatile oil from Serissa serissoides in different seasons]. PubMed: Impact odorants of different young white wines from the Canary Islands. PubMed: Effect of overexpression of Saccharomyces cerevisiae Pad1p on the resistance to phenylacrylic acids and lignocellulose hydrolysates under aerobic and oxygen-limited conditions. PubMed: Change in the flavor of black tea drink during heat processing. PubMed: Identification of potent odorants in Japanese green tea (Sen-cha). PubMed: Solid-phase extraction and HPLC determination of 4-vinyl guaiacol and its precursor, ferulic acid, in orange juice. PubMed: Compounds inhibiting prostaglandin synthesis isolated from Ipomoea pes-caprae.