Identification

Namefenugreek seed
IUPACtrigonella foenum-graecum l.
CAS Number977155-29-5
FDA UNIISearch

Regulatory

FEMA Number2484
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)977155-29-5 ; FENUGREEK (TRIGONELLA FOENUM-GRAECUM L.)
FDA RegulationFDA PART 101 -- FOOD LABELING

Physical Properties

Food Chemicals Codex Listed No

Organoleptic Properties

Odor Description at 100.00 %.
Taste Description fenugreek

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspices, other natural seasonings and flavorings
Recommendation for fenugreek seed usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes420.00000
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy15.00000
fruit ices15.00000
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

No supplier data available

Potential Uses

None Found

Natural Occurrence

fenugreek

Synonyms

fenugreek - seeds fenugreek seed powder fenugreek seed whole or ground, available as 100% certified organic frigonella foenum graecum seed trigonella foenum-graecum seed PubMed: Safety, Efficacy and Toxicological Evaluation of a Novel, Patented Anti-Diabetic Extract of Trigonella Foenum-Graecum Seed Extract (Fenfuro(TM)). PubMed: Effects of fenugreek (Trigonella foenum-graecum L.) seed on bone mechanical properties in rats. PubMed: Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line. PubMed: Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats. PubMed: Rhizobium tibeticum activated with a mixture of flavonoids alleviates nickel toxicity in symbiosis with fenugreek (Trigonella foenum graecum L.). PubMed: The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads. PubMed: Trigonella foenum-graecum L. seed mucilage-gellan mucoadhesive beads for controlled release of metformin HCl. PubMed: The selective cytotoxic anti-cancer properties and proteomic analysis of Trigonella Foenum-Graecum. PubMed: Antioxidant, oxidative DNA damage protective and antimicrobial activities of the plant Trigonella foenum-graecum. PubMed: Fenugreek seeds reduce aluminum toxicity associated with renal failure in rats. PubMed: Catalytic degradation of organic dyes using biosynthesized silver nanoparticles. PubMed: Protective effect of aqueous extract of seed of Psoralea corylifolia (Somraji) and seed of Trigonella foenum-graecum L. (Methi) in streptozotocin-induced diabetic rat: A comparative evaluation. PubMed: Pharmacological effects of Trigonella foenum-graecum L. in health and disease. PubMed: Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit. PubMed: Analytical and semipreparative separation of 25 (R/S)-spirostanol saponin diastereomers using supercritical fluid chromatography. PubMed: Galactomannan: a versatile biodegradable seed polysaccharide. PubMed: [Effect of fenugreek on the growth of different genesis tumors]. PubMed: A mechanism-based pharmacological evaluation of efficacy of Trigonella foenum graecum (fenugreek) seeds in regulation of dyslipidemia and oxidative stress in hyperlipidemic rats. PubMed: Chemomodulatory Effect of Trigonella foenum graecum (L.) Seed Extract on Two Stage Mouse Skin Carcinogenesis. PubMed: Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation. PubMed: Identification of an additional protein involved in mannan biosynthesis. PubMed: Antihyperglycemic and protective effects of Trigonella foenum graecum seed powder on biochemical alterations in alloxan diabetic rats. PubMed: Effect of Trigonella foenum-graecum seed powder on the antioxidant levels of high fat diet and low dose streptozotocin induced type II diabetic rats. PubMed: Ameliorative effects of standardized extract from Trigonella foenum-graecum L. seeds on painful peripheral neuropathy in rats. PubMed: Performance of some Ethiopian fenugreek (Trigonella foenum-graecum L.) germplasm collections as compared with the commercial variety Challa. PubMed: Deep EST profiling of developing fenugreek endosperm to investigate galactomannan biosynthesis and its regulation. PubMed: Beneficial effects of Trigonella foenum graecum and sodium orthovanadate on metabolic parameters in experimental diabetes. PubMed: Phytotherapy of alcoholism. PubMed: Antidiabetic and neuroprotective effects of Trigonella foenum-graecum seed powder in diabetic rat brain. PubMed: The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia. PubMed: Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts. PubMed: Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity. PubMed: Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues. PubMed: The Role of Adrenergic and Angiotensinergic Systems in Vascular Effect of Alcoholic of Extract Trigonella foenum-graecum Seed in Diabetic Rats. PubMed: Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats. PubMed: Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds. PubMed: Biochemical monitoring in fenugreek to develop functional food and medicinal plant variants. PubMed: The effect of fenugreek on the gene expression of arachidonic acid metabolizing enzymes. PubMed: Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues. PubMed: Modulation of quorum sensing controlled behaviour of bacteria by growing seedling, seed and seedling extracts of leguminous plants. PubMed: A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. PubMed: Fenugreek seeds reduce atherogenic diet-induced cholesterol gallstone formation in experimental mice. PubMed: Complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of Eugenia jambolana seed, Momordica charantia fruits, Gymnema sylvestre, and Trigonella foenum graecum seeds in rats. PubMed: Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor. PubMed: A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers. PubMed: Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents. PubMed: In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese rats. PubMed: Antihyperglycemic effect of Trigonella foenum-graecum (fenugreek) seed extract in alloxan-induced diabetic rats and its use in diabetes mellitus: a brief qualitative phytochemical and acute toxicity test on the extract. PubMed: Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract. PubMed: The Modifying Effects of Galactomannan from Canadian-Grown Fenugreek (Trigonella foenum-graecum L.) on the Glycemic and Lipidemic Status in Rats. PubMed: Allergenicity and antigenicity of fenugreek (Trigonella foenum-graecum) proteins in foods. PubMed: Protective action of fenugreek (Trigonella foenum graecum) seed polyphenols against alcohol-induced protein and lipid damage in rat liver. PubMed: Trigoxazonane, a monosubstituted trioxazonane from Trigonella foenum-graecum root exudate, inhibits Orobanche crenata seed germination. PubMed: Fenugreek (Trigonella foenum graecum) seed polyphenols protect liver from alcohol toxicity: a role on hepatic detoxification system and apoptosis. PubMed: Fenugreek seed (Trigonella foenum graecum) polyphenols inhibit ethanol-induced collagen and lipid accumulation in rat liver. PubMed: Composition and content of seed flavonoids in forage and grain legume crops. PubMed: Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by delaying carbohydrate digestion and absorption, and enhancing insulin action. PubMed: In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats. PubMed: Long-term effect of Trigonella foenum graecum and its combination with sodium orthovanadate in preventing histopathological and biochemical abnormalities in diabetic rat ocular tissues. PubMed: Low doses of vanadate and Trigonella synergistically regulate Na+/K + -ATPase activity and GLUT4 translocation in alloxan-diabetic rats. PubMed: Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells. PubMed: Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains. PubMed: Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella--a promising antidiabetic agent. PubMed: Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer. PubMed: Efficacy of lower doses of vanadium in restoring altered glucose metabolism and antioxidant status in diabetic rat lenses. PubMed: Trigonella foenum graecum seed powder protects against histopathological abnormalities in tissues of diabetic rats. PubMed: Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells. PubMed: Effects of sodium-orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes. PubMed: Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats. PubMed: Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity. PubMed: Oral administration of orthovanadate and Trigonella foenum graecum seed power restore the activities of mitochondrial enzymes in tissues of alloxan-induced diabetic rats. PubMed: [Studies on chemical constituents from the seed of Trigonella foenum-graecum]. PubMed: Mitigation of thyroxine-induced hyperglycaemia by two plant extracts. PubMed: Tobacco transgenic lines that express fenugreek galactomannan galactosyltransferase constitutively have structurally altered galactomannans in their seed endosperm cell walls. PubMed: In vitro effect of fenugreek extracts on intestinal sodium-dependent glucose uptake and hepatic glycogen phosphorylase A. PubMed: Variation in diosgenin levels among 10 accessions of fenugreek seeds produced in western Canada. PubMed: Transfer specificity of detergent-solubilized fenugreek galactomannan galactosyltransferase. PubMed: Restoration on tissue antioxidants by fenugreek seeds (Trigonella Foenum Graecum) in alloxan-diabetic rats. PubMed: Trigonellafoenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes. PubMed: Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent. PubMed: Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds. PubMed: Medicinal foodstuffs. XVII. Fenugreek seed. (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonellafoenum-graecum L. PubMed: Effects of vanadate, insulin and fenugreek (Trigonella foenum graecum) on creatine kinase levels in tissues of diabetic rat. PubMed: Modulation of some gluconeogenic enzyme activities in diabetic rat liver and kidney: effect of antidiabetic compounds. PubMed: Effect of antidiabetic compounds on glyoxalase I activity in experimental diabetic rat liver. PubMed: Effect of domestic processing on total and extractable calcium and zinc content of bathua (Chenopodium album) and fenugreek (Trigonella foenum graecum) leaves. PubMed: Acute and subchronic toxicity assessment of debitterized fenugreek powder in the mouse and rat. PubMed: Effect of fenugreek seeds on blood lipid peroxidation and antioxidants in diabetic rats. PubMed: Allergy to fenugreek (Trigonella foenum graecum). PubMed: Medicinal foodstuffs. IV. Fenugreek seed. (1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L. PubMed: Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol. PubMed: Characterization of the hypoglycemic effects of Trigonella foenum graecum seed. PubMed: Changes in the anti-nutritional factors of developing seeds and pod walls of fenugreek (Trigonella foenum graecum L.). PubMed: Effects of a fenugreek seed extract on feeding behaviour in the rat: metabolic-endocrine correlates. PubMed: Control of mannose/galactose ratio during galactomannan formation in developing legume seeds. PubMed: The effect of Trigonella foenum graecum (fenugreek) crude saponins on Hisex-type chicks. PubMed: Inhibitors of human and bovine trypsin and chymotrypsin in fenugreek (Trigonella foenum-graecum L.) seeds. Demonstration and purification. PubMed: Sensitivity of three leguminous crops to O3 as influenced by different stages of growth and development. PubMed: Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. PubMed: Direct observation of cell wall structure in living plant tissues by solid-state C NMR spectroscopy. PubMed: Effect of Trigonella foenum-graecum and Ammi majus on calcium oxalate urolithiasis in rats. PubMed: Biosynthesis of legume-seed galactomannans in vitro : Cooperative interactions of a guanosine 5'-diphosphate-mannose-linked (1→4)-β-D-manno-syltransferase and a uridine 5'-diphosphate-galactose-linked α-D-galactosyltransferase in particulate enzyme preparations from developing endosperms of fenugreek (Trigonella foenum-graecum L.) and guar (Cyamopsis tetragonoloba [L.] Taub.). PubMed: Antidiabetic effects of subfractions from fenugreek seeds in diabetic dogs. PubMed: Regulation of α-galactosidase activity and the hydrolysis of galactomannan in the endosperm of the fenugreek (Trigonella foenum-graecum L.) seed. PubMed: Galactomannan formation and guanosine 5'-diphosphate-mannose: galactomannan mannosyltransferase in developing seeds of fenugreek (Trigonella foenum-graecum L., leguminosae). PubMed: Mobilisation of the major stored reserves in the embryo of fenugreek (Trigonella foenum-graecum L., Leguminosae), and correlated enzyme activities. PubMed: Genotype dependent radiosensitivity of autotetraploids in Trigonella foenum-graecum L. PubMed: A dual rôle for the endosperm and its galactomannan reserves in the germinative physiology of fenugreek (Trigonella foenum-graecum L.), an endospermic leguminous seed. PubMed: Antagonism of cadmium and alloxan-induced hyperglycemia in rats by Trigonella foenum graecum. PubMed: Carbon dioxide assimilation in some aerial plant organs and tissues. PubMed: Reserve carbohydrate metabolism in germinating seeds of trigonella foenum-graecum L. (Leguminosae).