fenugreek seed
trigonella foenum-graecum seed
Identification
| Name | fenugreek seed |
| IUPAC | trigonella foenum-graecum l. |
| CAS Number | 977155-29-5 |
| FDA UNII | Search |
Regulatory
| FEMA Number | 2484 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 977155-29-5 ; FENUGREEK (TRIGONELLA FOENUM-GRAECUM L.) |
| FDA Regulation | FDA PART 101 -- FOOD LABELING |
Physical Properties
| Food Chemicals Codex Listed | No |
Organoleptic Properties
| Odor Description | at 100.00 %. |
| Taste Description | fenugreek |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | spices, other natural seasonings and flavorings |
| Recommendation for fenugreek seed usage levels up to | not for fragrance use. |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | 420.00000 |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 15.00000 |
| fruit ices | 15.00000 |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
fenugreek - seeds
fenugreek seed powder
fenugreek seed whole or ground, available as 100% certified organic
frigonella foenum graecum seed
trigonella foenum-graecum seed
PubMed:
Safety, Efficacy and Toxicological Evaluation of a Novel, Patented Anti-Diabetic Extract of Trigonella Foenum-Graecum Seed Extract (Fenfuro(TM)).
PubMed:
Effects of fenugreek (Trigonella foenum-graecum L.) seed on bone mechanical properties in rats.
PubMed:
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line.
PubMed:
Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats.
PubMed:
Rhizobium tibeticum activated with a mixture of flavonoids alleviates nickel toxicity in symbiosis with fenugreek (Trigonella foenum graecum L.).
PubMed:
The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.
PubMed:
Trigonella foenum-graecum L. seed mucilage-gellan mucoadhesive beads for controlled release of metformin HCl.
PubMed:
The selective cytotoxic anti-cancer properties and proteomic analysis of Trigonella Foenum-Graecum.
PubMed:
Antioxidant, oxidative DNA damage protective and antimicrobial activities of the plant Trigonella foenum-graecum.
PubMed:
Fenugreek seeds reduce aluminum toxicity associated with renal failure in rats.
PubMed:
Catalytic degradation of organic dyes using biosynthesized silver nanoparticles.
PubMed:
Protective effect of aqueous extract of seed of Psoralea corylifolia (Somraji) and seed of Trigonella foenum-graecum L. (Methi) in streptozotocin-induced diabetic rat: A comparative evaluation.
PubMed:
Pharmacological effects of Trigonella foenum-graecum L. in health and disease.
PubMed:
Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.
PubMed:
Analytical and semipreparative separation of 25 (R/S)-spirostanol saponin diastereomers using supercritical fluid chromatography.
PubMed:
Galactomannan: a versatile biodegradable seed polysaccharide.
PubMed:
[Effect of fenugreek on the growth of different genesis tumors].
PubMed:
A mechanism-based pharmacological evaluation of efficacy of Trigonella foenum graecum (fenugreek) seeds in regulation of dyslipidemia and oxidative stress in hyperlipidemic rats.
PubMed:
Chemomodulatory Effect of Trigonella foenum graecum (L.) Seed Extract on Two Stage Mouse Skin Carcinogenesis.
PubMed:
Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation.
PubMed:
Identification of an additional protein involved in mannan biosynthesis.
PubMed:
Antihyperglycemic and protective effects of Trigonella foenum graecum seed powder on biochemical alterations in alloxan diabetic rats.
PubMed:
Effect of Trigonella foenum-graecum seed powder on the antioxidant levels of high fat diet and low dose streptozotocin induced type II diabetic rats.
PubMed:
Ameliorative effects of standardized extract from Trigonella foenum-graecum L. seeds on painful peripheral neuropathy in rats.
PubMed:
Performance of some Ethiopian fenugreek (Trigonella foenum-graecum L.) germplasm collections as compared with the commercial variety Challa.
PubMed:
Deep EST profiling of developing fenugreek endosperm to investigate galactomannan biosynthesis and its regulation.
PubMed:
Beneficial effects of Trigonella foenum graecum and sodium orthovanadate on metabolic parameters in experimental diabetes.
PubMed:
Phytotherapy of alcoholism.
PubMed:
Antidiabetic and neuroprotective effects of Trigonella foenum-graecum seed powder in diabetic rat brain.
PubMed:
The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia.
PubMed:
Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts.
PubMed:
Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity.
PubMed:
Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues.
PubMed:
The Role of Adrenergic and Angiotensinergic Systems in Vascular Effect of Alcoholic of Extract Trigonella foenum-graecum Seed in Diabetic Rats.
PubMed:
Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats.
PubMed:
Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds.
PubMed:
Biochemical monitoring in fenugreek to develop functional food and medicinal plant variants.
PubMed:
The effect of fenugreek on the gene expression of arachidonic acid metabolizing enzymes.
PubMed:
Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.
PubMed:
Modulation of quorum sensing controlled behaviour of bacteria by growing seedling, seed and seedling extracts of leguminous plants.
PubMed:
A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects.
PubMed:
Fenugreek seeds reduce atherogenic diet-induced cholesterol gallstone formation in experimental mice.
PubMed:
Complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of Eugenia jambolana seed, Momordica charantia fruits, Gymnema sylvestre, and Trigonella foenum graecum seeds in rats.
PubMed:
Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor.
PubMed:
A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers.
PubMed:
Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents.
PubMed:
In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese rats.
PubMed:
Antihyperglycemic effect of Trigonella foenum-graecum (fenugreek) seed extract in alloxan-induced diabetic rats and its use in diabetes mellitus: a brief qualitative phytochemical and acute toxicity test on the extract.
PubMed:
Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract.
PubMed:
The Modifying Effects of Galactomannan from Canadian-Grown Fenugreek (Trigonella foenum-graecum L.) on the Glycemic and Lipidemic Status in Rats.
PubMed:
Allergenicity and antigenicity of fenugreek (Trigonella foenum-graecum) proteins in foods.
PubMed:
Protective action of fenugreek (Trigonella foenum graecum) seed polyphenols against alcohol-induced protein and lipid damage in rat liver.
PubMed:
Trigoxazonane, a monosubstituted trioxazonane from Trigonella foenum-graecum root exudate, inhibits Orobanche crenata seed germination.
PubMed:
Fenugreek (Trigonella foenum graecum) seed polyphenols protect liver from alcohol toxicity: a role on hepatic detoxification system and apoptosis.
PubMed:
Fenugreek seed (Trigonella foenum graecum) polyphenols inhibit ethanol-induced collagen and lipid accumulation in rat liver.
PubMed:
Composition and content of seed flavonoids in forage and grain legume crops.
PubMed:
Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by delaying carbohydrate digestion and absorption, and enhancing insulin action.
PubMed:
In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats.
PubMed:
Long-term effect of Trigonella foenum graecum and its combination with sodium orthovanadate in preventing histopathological and biochemical abnormalities in diabetic rat ocular tissues.
PubMed:
Low doses of vanadate and Trigonella synergistically regulate Na+/K + -ATPase activity and GLUT4 translocation in alloxan-diabetic rats.
PubMed:
Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells.
PubMed:
Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains.
PubMed:
Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella--a promising antidiabetic agent.
PubMed:
Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer.
PubMed:
Efficacy of lower doses of vanadium in restoring altered glucose metabolism and antioxidant status in diabetic rat lenses.
PubMed:
Trigonella foenum graecum seed powder protects against histopathological abnormalities in tissues of diabetic rats.
PubMed:
Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells.
PubMed:
Effects of sodium-orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes.
PubMed:
Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats.
PubMed:
Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity.
PubMed:
Oral administration of orthovanadate and Trigonella foenum graecum seed power restore the activities of mitochondrial enzymes in tissues of alloxan-induced diabetic rats.
PubMed:
[Studies on chemical constituents from the seed of Trigonella foenum-graecum].
PubMed:
Mitigation of thyroxine-induced hyperglycaemia by two plant extracts.
PubMed:
Tobacco transgenic lines that express fenugreek galactomannan galactosyltransferase constitutively have structurally altered galactomannans in their seed endosperm cell walls.
PubMed:
In vitro effect of fenugreek extracts on intestinal sodium-dependent glucose uptake and hepatic glycogen phosphorylase A.
PubMed:
Variation in diosgenin levels among 10 accessions of fenugreek seeds produced in western Canada.
PubMed:
Transfer specificity of detergent-solubilized fenugreek galactomannan galactosyltransferase.
PubMed:
Restoration on tissue antioxidants by fenugreek seeds (Trigonella Foenum Graecum) in alloxan-diabetic rats.
PubMed:
Trigonellafoenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes.
PubMed:
Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent.
PubMed:
Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds.
PubMed:
Medicinal foodstuffs. XVII. Fenugreek seed. (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonellafoenum-graecum L.
PubMed:
Effects of vanadate, insulin and fenugreek (Trigonella foenum graecum) on creatine kinase levels in tissues of diabetic rat.
PubMed:
Modulation of some gluconeogenic enzyme activities in diabetic rat liver and kidney: effect of antidiabetic compounds.
PubMed:
Effect of antidiabetic compounds on glyoxalase I activity in experimental diabetic rat liver.
PubMed:
Effect of domestic processing on total and extractable calcium and zinc content of bathua (Chenopodium album) and fenugreek (Trigonella foenum graecum) leaves.
PubMed:
Acute and subchronic toxicity assessment of debitterized fenugreek powder in the mouse and rat.
PubMed:
Effect of fenugreek seeds on blood lipid peroxidation and antioxidants in diabetic rats.
PubMed:
Allergy to fenugreek (Trigonella foenum graecum).
PubMed:
Medicinal foodstuffs. IV. Fenugreek seed. (1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L.
PubMed:
Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol.
PubMed:
Characterization of the hypoglycemic effects of Trigonella foenum graecum seed.
PubMed:
Changes in the anti-nutritional factors of developing seeds and pod walls of fenugreek (Trigonella foenum graecum L.).
PubMed:
Effects of a fenugreek seed extract on feeding behaviour in the rat: metabolic-endocrine correlates.
PubMed:
Control of mannose/galactose ratio during galactomannan formation in developing legume seeds.
PubMed:
The effect of Trigonella foenum graecum (fenugreek) crude saponins on Hisex-type chicks.
PubMed:
Inhibitors of human and bovine trypsin and chymotrypsin in fenugreek (Trigonella foenum-graecum L.) seeds. Demonstration and purification.
PubMed:
Sensitivity of three leguminous crops to O3 as influenced by different stages of growth and development.
PubMed:
Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes.
PubMed:
Direct observation of cell wall structure in living plant tissues by solid-state C NMR spectroscopy.
PubMed:
Effect of Trigonella foenum-graecum and Ammi majus on calcium oxalate urolithiasis in rats.
PubMed:
Biosynthesis of legume-seed galactomannans in vitro : Cooperative interactions of a guanosine 5'-diphosphate-mannose-linked (1â4)-β-D-manno-syltransferase and a uridine 5'-diphosphate-galactose-linked α-D-galactosyltransferase in particulate enzyme preparations from developing endosperms of fenugreek (Trigonella foenum-graecum L.) and guar (Cyamopsis tetragonoloba [L.] Taub.).
PubMed:
Antidiabetic effects of subfractions from fenugreek seeds in diabetic dogs.
PubMed:
Regulation of α-galactosidase activity and the hydrolysis of galactomannan in the endosperm of the fenugreek (Trigonella foenum-graecum L.) seed.
PubMed:
Galactomannan formation and guanosine 5'-diphosphate-mannose: galactomannan mannosyltransferase in developing seeds of fenugreek (Trigonella foenum-graecum L., leguminosae).
PubMed:
Mobilisation of the major stored reserves in the embryo of fenugreek (Trigonella foenum-graecum L., Leguminosae), and correlated enzyme activities.
PubMed:
Genotype dependent radiosensitivity of autotetraploids in Trigonella foenum-graecum L.
PubMed:
A dual rôle for the endosperm and its galactomannan reserves in the germinative physiology of fenugreek (Trigonella foenum-graecum L.), an endospermic leguminous seed.
PubMed:
Antagonism of cadmium and alloxan-induced hyperglycemia in rats by Trigonella foenum graecum.
PubMed:
Carbon dioxide assimilation in some aerial plant organs and tissues.
PubMed:
Reserve carbohydrate metabolism in germinating seeds of trigonella foenum-graecum L. (Leguminosae).