valerian rhizome/root
plant material derived from the dried rhizomes and roots of the valerian, valeriana officinalis l., valerianaceae
Identification
| Name | valerian rhizome/root |
| IUPAC | valeriana officinalis l. rhizome/root |
| CAS Number | 8057-49-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | soothing agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mammal (species unspecified) LD50 975 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | soothing agents |
| Recommendation for valerian rhizome/root usage levels up to | not for fragrance use. |
| Recommendation for valerian rhizome/root flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
plant material derived from the dried rhizomes and roots of the valerian, valeriana officinalis l., valerianaceae
valerian bulgaria organic
valerian rhizome/root
valeriana officinalis rhizome/root
PubMed:
Plant hairy root cultures as plasmodium modulators of the slime mold emergent computing substrate Physarum polycephalum.
PubMed:
Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish).
PubMed:
Valeriana officinalis Extracts Ameliorate Neuronal Damage by Suppressing Lipid Peroxidation in the Gerbil Hippocampus Following Transient Cerebral Ischemia.
PubMed:
Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites.
PubMed:
The influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model.
PubMed:
Can Valeriana officinalis root extract prevent early postoperative cognitive dysfunction after CABG surgery? A randomized, double-blind, placebo-controlled trial.
PubMed:
Valerian: no evidence for clinically relevant interactions.
PubMed:
Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway.
PubMed:
Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation.
PubMed:
Functional identification of valerena-1,10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in Valeriana officinalis.
PubMed:
Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis).
PubMed:
Extract of valerian root (Valeriana officinalis L.) vs. placebo in treatment of obsessive-compulsive disorder: a randomized double-blind study.
PubMed:
Telemetry as a tool to measure sedative effects of a valerian root extract and its single constituents in mice.
PubMed:
Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.
PubMed:
Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine.
PubMed:
Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian.
PubMed:
Root colonization by symbiotic arbuscular mycorrhizal fungi increases sesquiterpenic acid concentrations in Valeriana officinalis L.
PubMed:
Pinoresinol-4,4'-di-O-beta-D-glucoside from Valeriana officinalis root stimulates calcium mobilization and chemotactic migration of mouse embryo fibroblasts.
PubMed:
Determination of metal content in valerian root phytopharmaceutical derivatives by atomic spectrometry.
PubMed:
In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4.
PubMed:
Stability control of valerian ground material and extracts: a new HPLC-method for the routine quantification of valerenic acids and lignans.
PubMed:
Analysis of responses to valerian root extract in the feline pulmonary vascular bed.
PubMed:
(-)-3 beta,4 beta-epoxyvalerenic acid from Valeriana officinalis.
PubMed:
[Clinical studies on the treatment of coronary heart disease with Valeriana officinalis var latifolia].
PubMed:
Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier.
PubMed:
High-yield production of valepotriates by hairy root cultures of Valeriana officnalis L. var. sambucifolia Mikan.
PubMed:
Valepotriate content in different in vitro cultures of Valerianaceae and characterization of Valeriana officinalis L. callus during a growth period.
PubMed:
Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man.
PubMed:
[Biological titration of the root of Valeriana officinalis].