dextro-neomenthol

D-neomenthol

CAS: 2216-52-6 C10 H20 O MW: 156.26860000 mentholic mentholic

Identification

Namedextro-neomenthol
CAS Number2216-52-6
EINECS218-691-4
FDA UNII42RE7MA7PA
Molecular FormulaC10 H20 O
Molecular Weight156.26860000
MDL NumberMFCD00062980
Beilstein2037488
CoE Number2028

Regulatory

JECFA Food Flavoring428 D-neo-menthol
DG SANTE Food Flavourings02.063 D-neomenthol
FEMA Number2666
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)2216-52-6 ; D-NEOMENTHOL
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless liquid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.90000 to 0.90300 @ 20.00 °C., 0.89600 to 0.90300 @ 20.00 °C.
Pounds per Gallon - (est). 7.498 to 7.523
Pounds per Gallon - est. 7.464 to 7.523
Refractive Index 1.45900 to 1.46200 @ 20.00 °C., 1.45900 to 1.46000 @ 20.00 °C.
Optical Rotation +15.0 to +20.0
Melting Point -22.00 °C. @ 760.00 mm Hg
Boiling Point 95.00 °C. @ 12.00 mm Hg, 107.00 to 108.00 °C. @ 20.00 mm Hg
Vapor Pressure 0.032000 mmHg @ 25.00 °C. (est)
Flash Point 180.00 °F. TCC ( 82.22 °C. )
logP (o/w) 3.216 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description at 10.00 % in dipropylene glycol.
Taste Description cooling mentholic minty peppermint

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for dextro-neomenthol usage levels up to3.0000 % in the fragrance concentrate.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FR mint FR peppermint FR spearmint FR wintergreen

Natural Occurrence

buchu leaf cabbage leaf cornmint cornmint leaf peppermint leaf spearmint leaf spearmint leaf oil spearmint oil water mint leaf

Synonyms

cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2S,5R)- (+)-neo menthol (1R,3S,4S)-(+)- menthol (1S,2S,5R)-(+)-neo menthol D-neo menthol D-neo- menthol (1S,2S,5R)-5- methyl-2-(1-methyl ethyl) cyclohexanol (1S-(1alpha, 2alpha,5beta))-5- methyl-2-(1-methyl ethyl) cyclohexanol (1S-(1beta, 2beta,5alpha))-5- methyl-2-(1-methyl ethyl) cyclohexanol (1S,2S,5R)-5- methyl-2-propan-2-ylcyclohexan-1-ol 2-iso propyl-5-methyl cyclohexanol stereoisomer D-beta- pulegomenthol dextro-beta- pulegomenthol PubMed: Effect of l-menthol on laryngeal receptors. PubMed: The effects of menthol isomers on nasal sensation of airflow. PubMed: Metabolism of Monoterpenes : Evidence for the Function of Monoterpene Catabolism in Peppermint (Mentha piperita) Rhizomes. PubMed: Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes. PubMed: Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves. PubMed: Demonstration of the Intercellular Compartmentation of l-Menthone Metabolism in Peppermint (Mentha piperita) Leaves. PubMed: Metabolism of Monoterpenes : EVIDENCE FOR COMPARTMENTATION OF l-MENTHONE METABOLISM IN PEPPERMINT (MENTHA PIPERITA) LEAVES. PubMed: Studies in detoxication: The biological reduction of l-menthone to d-neomenthol and of d-isomenthone to d-isomenthol in the rabbit. The conjugation of d-neomenthol with glucuronic acid.