chrysarobin
araroba powder
Identification
| Name | chrysarobin |
| IUPAC | chrysarobin |
| CAS Number | 8001-71-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for chrysarobin usage levels up to | not for fragrance use. |
| Recommendation for chrysarobin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
andira araroba aguiar.
araroba powder
bahia powder
brazil powder
chrysatobine
goa powder
ringworm powder
voucapoua araroba
PubMed:
Characterization of physical and chemical defenses in the hemlock woolly adelgid.
PubMed:
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
PubMed:
Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.
PubMed:
Potential feeding deterrents found in hemlock woolly adelgid, Adelges tsugae.
PubMed:
Cassia occidentalis L.: a review on its ethnobotany, phytochemical and pharmacological profile.
PubMed:
Activation of epidermal akt by diverse mouse skin tumor promoters.
PubMed:
Anthraquinones as defensive compounds in eggs of Galerucini leaf beetles: biosynthesis by the beetles?
PubMed:
Defensive components in insect eggs: are anthraquinones produced during egg development?
PubMed:
Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis.
PubMed:
Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation.
PubMed:
Collagenase induction promotes mouse tumorigenesis by two independent pathways.
PubMed:
Skin tumorigenesis by initiators and promoters of different chemical structures in lines of mice selectively bred for resistance (Car-r) or susceptibility (Car-s) to two-stage skin carcinogenesis.
PubMed:
Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice.
PubMed:
Alterations in cholesterol sulfate and its biosynthetic enzyme during multistage carcinogenesis in mouse skin.
PubMed:
Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol.
PubMed:
Inhibition of the glucocorticoid receptor expression by diverse tumor promoters in SENCAR mouse epidermis.
PubMed:
Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters.
PubMed:
Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice.
PubMed:
Effect of diverse tumor promoters on the expression of gap-junctional proteins connexin (Cx)26, Cx31.1, and Cx43 in SENCAR mouse epidermis.
PubMed:
The effects of calcium antagonists on anthrone skin tumor promotion and promoter-related effects in SENCAR mice.
PubMed:
Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice.
PubMed:
Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis.
PubMed:
Genetic factors controlling responsiveness to skin tumor promotion in mice.
PubMed:
Skin carcinogenesis: characteristics, mechanisms, and prevention.
PubMed:
Loss of mouse epidermal protein kinase C isozyme activities following treatment with phorbol ester and non-phorbol ester tumor promoters.
PubMed:
An EPR study of free radicals formed by antipsoriatic and tumor-promoting 9-anthrones in nonpolar solvents.
PubMed:
Toxicity of structurally related anthraquinones and anthrones to mammalian cells in vitro.
PubMed:
Antipsoriatic anthrones with modulated redox properties. 2. Novel derivatives of chrysarobin and isochrysarobin--antiproliferative activity and 5-lipoxygenase inhibition.
PubMed:
Dose-response relationship in multistage carcinogenesis: promoters.
PubMed:
Polarographic and absorptive stripping voltammetric determination of mitoxantrone, emodin and chrysarobin using mercury and glassy carbon electrodes.
PubMed:
Inhibition of chrysarobin skin tumor promotion in SENCAR mice by antioxidants.
PubMed:
Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
PubMed:
History of the treatment of psoriasis.
PubMed:
Anthralin, a non-TPA type tumor promoter, synergistically enhances phorbol ester-caused prostaglandin E2 release from primary cultured mouse epidermal cells.
PubMed:
Phorbol ester-mediated suppression of cytochrome P450 Cyp1a-1 induction in murine skin: involvement of protein kinase C.
PubMed:
[The tree, from which chrysarobin was isolated].
PubMed:
Enhanced induction of epidermal ornithine decarboxylase activity in C57BL/6 compared to DBA/2 mice by protein kinase C-activating skin tumor promoters: relevance to genetically mediated differences in promotion susceptibility.
PubMed:
[75 years of Cignolin].
PubMed:
Evidence for a common genetic pathway controlling susceptibility to mouse skin tumor promotion by diverse classes of promoting agents.
PubMed:
Evidence for autocrine/paracrine growth stimulation by transforming growth factor-alpha during the process of skin tumor promotion.
PubMed:
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
PubMed:
Differential mechanism for the inhibition of epidermal growth factor binding to its receptor on mouse keratinocytes by anthrones and phorbol esters.
PubMed:
Differential effects of various skin tumor-promoting agents on prostaglandin E2 release from primary cultures of mouse epidermal cells.
PubMed:
[Chemical instability of the antipsoriatic dithranol and chrysarobin in aqueous systems: oxidation behavior].
PubMed:
[Synthesis, characterization, racemation and biochemical studies on 10-acylderivatives of chrysarobin: sorbylchrysarobin, beta-carbethoxypropionylchrysarobin and senecioylchrysarobin].
PubMed:
[Purification, glucose-6-phosphate dehydrogenase inhibition, and HPLC analysis of four 1,8-dihydroxyanthrones].
PubMed:
[The history of dermatology. On the 150th birthday of Heinrich Köbner].
PubMed:
Histologic alterations produced by chrysarobin (1,8-dihydroxy-3-methyl-9-anthrone) in SENCAR mouse skin: relationship to skin tumor promoting activity.
PubMed:
Tumor progression in Sencar mouse skin as a function of initiator dose and promoter dose, duration, and type.
PubMed:
Alterations in epidermal polyamine levels and DNA synthesis following topical treatment with chrysarobin in SENCAR mice.
PubMed:
Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas.
PubMed:
Structure-activity relationships for epidermal ornithine decarboxylase induction and skin tumor promotion by anthrones.
PubMed:
Modulation of chrysarobin skin tumor promotion.
PubMed:
Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
PubMed:
Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents.
PubMed:
Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice.
PubMed:
Effect of application frequency on epidermal ornithine decarboxylase induction by chrysarobin in SENCAR mice.
PubMed:
Mechanism of mouse skin tumor promotion by chrysarobin.
PubMed:
Anthralin: historical and current perspectives.
PubMed:
Tumor promoting activity of 1,8-dihydroxy-3-methyl-9-anthrone (chrysarobin) in female SENCAR mice.
PubMed:
Anthralin and chrysarobin: a reexamination of the origins and early use.
PubMed:
Structure specificity of the antipsoriatic anthrones.
PubMed:
[Zonal psoriasis].
PubMed:
On the molecular structure of some prostaglandin receptors.
PubMed:
[Introduction of chrysarobin into Europe. A contribution to the history of dermatotherapy].
PubMed:
Thin-layer chromatographic separation and identification of the main constituents of Chrysarobin.
PubMed:
[Investigations on the mechanism of action of chrysarobin and dithranol (=Cignolin) in psoriasis. Indications for a cytostatic action of these drugs].
PubMed:
PSORIASIS; A STATISTICAL STUDY OF THE GOECKERMAN AND THE CHRYSAROBIN THERAPIES, AND OF VARIOUS FACTORS INFLUENCING THE CLINIC.
PubMed:
[Experimental studies of the mechanism of action of chrysarobin and dithranol in psoriasis (evidence for a cytostatic effect on the epidermis)].
PubMed:
[ATTEMPT AT STANDARDIZATION OF CHRYSAROBIN WITH TUBIFEX].
PubMed:
[ON PRODUCTION OF A PREPARATION SIMILAR TO CHRYSAROBIN FROM RHEUM PALMATUM VAR. TANGUTICUM MAXIM].
PubMed:
[On the utilization of natural resources for chrysarobin production].
PubMed:
Chloranil in the treatment of psoriasis; a substitute for chrysarobin.
PubMed:
Remarks on chronic seborrheic dermatitis of the external ear with special reference to treatment with chrysarobin.
PubMed:
[Our experience with chrysarobin therapy in very weak concentrations].
PubMed:
[Pharmacology of chrysarobin].
PubMed:
Case of Unusual Tolerance in Chrysarobin.
PubMed:
Deductions from Three Hundred and Nineteen Observations of the Action of Chrysarobin-a New Emeticpurge.
PubMed:
Anthralin/dithranol in dermatology.