oosponol

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1H-2-benzopyran-1-one, 8-hydroxy-4-(hydroxyacetyl)-

CAS: 146-04-3 C11 H8 O5 MW: 220.18076000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Nameoosponol
CAS Number146-04-3
FDA UNIISearch
Molecular FormulaC11 H8 O5
Molecular Weight220.18076000
Nikkaji NumberJ71.270A
Beilstein1287762

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 485.93 °C. @ 760.00 mm Hg (est)
Flash Point 390.00 °F. TCC ( 198.90 °C. ) (est)
logP (o/w) 0.789 (est)
Soluble in water, 9.223e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD50 40 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for oosponol usage levels up tonot for fragrance use.
Recommendation for oosponol flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

antifungal

Natural Occurrence

not found in nature

Synonyms

1H-2- benzopyran-1-one, 8-hydroxy-4-(2-hydroxyacetyl)- 1H-2- benzopyran-1-one, 8-hydroxy-4-(hydroxyacetyl)- iso coumarin, 4-glycolyl-8-hydroxy- 4- glycoloyl-8-hydroxy-1H-isochromen-1-one 4- glycolyl-8-hydroxy-isocoumarin 4- glycolyl-8-hydroxyisocoumarin 8- hydroxy-4-(2-hydroxyacetyl)isochromen-1-one 8- hydroxy-4-(hydroxyacetyl)-1H-2-benzopyran-1-one lenzitin PubMed: Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. PubMed: Chemical reactivity of the toxin oosponol from Gloeophyllum abietinum with nucleophilic agents. PubMed: Secondary fungal metabolites and their biological activities, III. Further metabolites from dual cultures of the antagonistic basidiomycetes Heterobasidion annosum and Gloeophyllum abietinum. PubMed: Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds. PubMed: Inhibition of compound 48/80-mediated histamine release from isolated rat mast cells by oosponol-related compounds (4-acyl-isocoumarins). PubMed: Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. PubMed: Studies on the metabolic products of Oospora astringenes. VII. Biogenesis of oospolactone and oosponol.