diethofencarb
isopropyl 3,4-diethoxyphenylcarbamate
Identification
| Name | diethofencarb |
| IUPAC | propan-2-yl N-(3,4-diethoxyphenyl)carbamate |
| CAS Number | 87130-20-9 |
| FDA UNII | 421BLT77U4 |
| Molecular Formula | C14 H21 N O4 |
| Molecular Weight | 267.32517000 |
| MDL Number | MFCD00274591 |
| Nikkaji Number | J135.062E |
| XlogP3 | 2.80 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 100.30 °C. @ 760.00 mm Hg |
| Boiling Point | 325.90 °C. @ 760.00 mm Hg (est) |
| Flash Point | 304.00 °F. TCC ( 150.90 °C. ) (est) |
| logP (o/w) | 2.910 |
| Soluble in | water, 26.6 mg/L @ 20 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-duck LD50 > 2250 mg/kg |
| Dermal Toxicity | skin-mouse LD50 > 5000 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 > 1050 mg/m3 |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for diethofencarb usage levels up to | not for fragrance use. |
| Recommendation for diethofencarb flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
carbamic acid, (3,4-diethoxyphenyl)-, 1-methylethyl ester
1-
methylethyl (3,4-diethoxyphenyl)carbamate
powmil
powmyl
powmyl WP
propan-2-yl N-(3,4-diethoxyphenyl)carbamate
iso
propyl 3,4-diethoxycarbanilate
iso
propyl 3,4-diethoxyphenylcarbamate
PubMed:
Graphene-modified TiO2 nanotube arrays as an adsorbent in micro-solid phase extraction for determination of carbamate pesticides in water samples.
PubMed:
Air-Assisted Liquid Liquid-Microextraction for the Analysis of Fungicides from Environmental Water and Juice Samples.
PubMed:
Graphene based solid phase extraction combined with ultra high performance liquid chromatography-tandem mass spectrometry for carbamate pesticides analysis in environmental water samples.
PubMed:
Analysis of 10 systemic pesticide residues in various baby foods using liquid chromatography-tandem mass spectrometry.
PubMed:
Fungicide resistance of Botrytis cinerea in tomato greenhouses in the Canary Islands and effectiveness of non-chemical treatments against gray mold.
PubMed:
Extraction of carbamate pesticides in fruit samples by graphene reinforced hollow fibre liquid microextraction followed by high performance liquid chromatographic detection.
PubMed:
Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates.
PubMed:
Ionic liquid-based ultrasound-assisted emulsification microextraction coupled with high performance liquid chromatography for the determination of four fungicides in environmental water samples.
PubMed:
Graphene grafted silica-coated Fe3O4 nanocomposite as absorbent for enrichment of carbamates from cucumbers and pears prior to HPLC.
PubMed:
Temperature-controlled ionic liquid dispersive liquid-phase microextraction combined with HPLC with ultraviolet detector for the determination of fungicides.
PubMed:
Development of sensitive determination method for fungicides from environmental water samples with Titanate nanotube array micro-solid phase extraction prior to high performance liquid chromatography.
PubMed:
In-syringe demulsified dispersive liquid-liquid microextraction and high performance liquid chromatography-mass spectrometry for the determination of trace fungicides in environmental water samples.
PubMed:
Preparation of a graphene-based magnetic nanocomposite for the extraction of carbamate pesticides from environmental water samples.
PubMed:
Application of an ultrasound-assisted surfactant-enhanced emulsification microextraction method for the analysis of diethofencarb and pyrimethanil fungicides in water and fruit juice samples.
PubMed:
Dispersive liquid-liquid microextraction based on the solidification of a floating organic droplet for simultaneous analysis of diethofencarb and pyrimethanil in apple pulp and peel.
PubMed:
Application of dispersive liquid-liquid microextraction and reversed phase-high performance liquid chromatography for the determination of two fungicides in environmental water samples.
PubMed:
Ultrasound-assisted surfactant-enhanced emulsification microextraction for the determination of carbamate pesticides in water samples by high performance liquid chromatography.
PubMed:
Temperature-controlled ionic liquid-dispersive liquid-phase microextraction for preconcentration of chlorotoluron, diethofencarb and chlorbenzuron in water samples.
PubMed:
Pesticide residue monitoring in Korean agricultural products, 2003-05.
PubMed:
Carbamates synergize the toxicity of acrinathrin in resistant western flower thrips (Thysanoptera: Thripidae).
PubMed:
Application of dispersive liquid-liquid microextraction combined with high-performance liquid chromatography to the determination of carbamate pesticides in water samples.
PubMed:
Genotyping of benzimidazole-resistant and dicarboximide-resistant mutations in Botrytis cinerea using real-time polymerase chain reaction assays.
PubMed:
In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.
PubMed:
Determination of metolcarb and diethofencarb in apples and apple juice by solid-phase microextraction-high performance liquid chromatography.
PubMed:
Screening preharvest/postharvest strategies to prevent fruit rot decay.
PubMed:
Molecular characterization of benzimidazole-resistant isolates of Cladosporium fulvum.
PubMed:
Sensitive determination of fungicides and prometryn in environmental water samples using multiwalled carbon nanotubes solid-phase extraction cartridge.
PubMed:
[Determination of carbamate pesticides in reservoir water by hollow fiber-based liquid phase microextraction coupled with high performance liquid chromatography].
PubMed:
Development and validation of a multi-residue method for pesticide determination in honey using on-column liquid-liquid extraction and liquid chromatography-tandem mass spectrometry.
PubMed:
Analysis of carbamate and phenylurea pesticide residues in fruit juices by solid-phase microextraction and liquid chromatography-mass spectrometry.
PubMed:
[Investigation of pesticide residues in foods distributed in Kitakyushu City].
PubMed:
Metabolism of diethofencarb (isopropyl 3,4-diethoxyphenylcarbamate) in rats: identification of metabolites in urine.
PubMed:
Clay-catalyzed nitration of a carbamate fungicide diethofencarb.
PubMed:
Metabolism of fungicide diethofencarb in grape (Vitis vinifera L.): definitive identification of thiolactic acid conjugated metabolites.
PubMed:
The influence of fungicides on the growth of Trichoderma asperellum.
PubMed:
Mechanisms of resistance to fungicides in field strains of Botrytis cinerea.
PubMed:
Focused microwave assistance for extracting some pesticide residues from strawberries into water before their determination by SPME/HPLC/DAD.
PubMed:
Solid phase microextraction of pesticide residues from strawberries.
PubMed:
Fungal beta-tubulin, expressed as a fusion protein, binds benzimidazole and phenylcarbamate fungicides.
PubMed:
Amino-acid alterations in the beta-tubulin gene of Neurospora crassa that confer resistance to carbendazim and diethofencarb.
PubMed:
Effects of diethofencarb on thyroid function and hepatic UDP-glucuronyltransferase activity in rats.
PubMed:
A single amino-acid substitution in the beta-tubulin gene of Neurospora confers both carbendazim resistance and diethofencarb sensitivity.
PubMed:
Age-related changes in metabolism of diethofencarb: relationship between metabolism in rat and hepatic drug-metabolizing enzyme activities.