mepanipyrim

2-pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)-

CAS: 110235-47-7 C14 H13 N3 MW: 223.27861000

Identification

Namemepanipyrim
IUPAC4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine
CAS Number110235-47-7
FDA UNIIB150X76OJY
Molecular FormulaC14 H13 N3
Molecular Weight223.27861000
MDL NumberMFCD01656050
Nikkaji NumberJ583.868A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 132.80 °C. @ 760.00 mm Hg
Boiling Point 418.20 °C. @ 760.00 mm Hg (est)
Flash Point 404.00 °F. TCC ( 206.70 °C. ) (est)
logP (o/w) 3.280
Soluble in water, 3.1 mg/L @ 20 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-duck LD50 > 2250 mg/kg
Dermal Toxicityskin-rat LD50 > 2000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for mepanipyrim usage levels up tonot for fragrance use.
Recommendation for mepanipyrim flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

N-(4- methyl-6-prop-1-ynylpyrimidin-2-yl)aniline (IUPAC) 4- methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine 4- methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine 2- pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)- PubMed: Toxicity evaluation of new agricultural fungicides in primary cultured cortical neurons. PubMed: Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method. PubMed: [Determination of six novel amide fungicides in vegetables and fruits by liquid chromatography-tandem mass spectrometry]. PubMed: Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis. PubMed: Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples. PubMed: Mepanipyrim haptens and antibodies with nanomolar affinity. PubMed: Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. PubMed: Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS. PubMed: [Determination of fungicide anilinopyrimidine residues in food by series solid phase extraction-high performance liquid chromatography-tandem mass spectrometry]. PubMed: Planar solid phase extraction clean-up for pesticide residue analysis in tea by liquid chromatography-mass spectrometry. PubMed: Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming. PubMed: Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight. PubMed: Effect of anilinopyrimidine resistance on aflatoxin production and fitness parameters in Aspergillus parasiticus Speare. PubMed: Metabolism of a fungicide mepanipyrim by soil fungus Cunninghamella elegans ATCC36112. PubMed: Regio- and chemoselective metalation of chloropyrimidine derivatives with TMPMgCl x LiCl and TMP(2)Zn x 2 MgCl(2) x 2 LiCl. PubMed: Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. PubMed: Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine. PubMed: Degradation of anilinopyrimidine fungicides photoinduced by iron(III)-polycarboxylate complexes. PubMed: Characterisation by high-performance liquid chromatography-multiple mass spectrometry of intermediate compounds formed from mepanipyrim photoinduced degradation. PubMed: Synthesis and structure-activity study of fungicidal anilinopyrimidines leading to mepanipyrim (KIF-3535) as an anti-Botrytis agent. PubMed: Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion. PubMed: Pesticide residues in grapes, wine, and their processing products. PubMed: Pesticides in fermentative processes of wine. PubMed: Mepanipyrim, a new fungicide, inhibits intracellular transport of very low density lipoprotein in rat hepatocytes. PubMed: Gas chromatographic determination of azoxystrobin, fluazinam, kresoxim-methyl, mepanipyrim, and tetraconazole in grapes, must, and wine. PubMed: Effects of mepanipyrim on lipid metabolism in rats. PubMed: Mepanipyrim induces fatty liver in rats but not in mice and dogs. PubMed: Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol.