ortho-methoxycinnamaldehyde

o-methoxycinnamaldehyde

CAS: 1504-74-1 C10 H10 O2 MW: 162.18810000 spicy spicy

Identification

Nameortho-methoxycinnamaldehyde
IUPAC3-(2-methoxyphenyl)prop-2-enal
CAS Number1504-74-1
EINECS216-131-3
FDA UNII4940G3R6HE
Molecular FormulaC10 H10 O2
Molecular Weight162.18810000
MDL NumberMFCD00007001
Beilstein2436856
CoE Number571
XlogP31.70 (est)

Regulatory

JECFA Food Flavoring688 o-methoxycinnamaldehyde
DG SANTE Food Flavourings05.048 2-methoxycinnamaldehyde
FEMA Number3181
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)1504-74-1 ; O-METHOXYCINNAMALDEHYDE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance pale yellow crystals (est)
Assay 94.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 44.00 to 48.00 °C. @ 760.00 mm Hg
Boiling Point 160.00 to 161.00 °C. @ 12.00 mm Hg, 295.00 °C. @ 760.00 mm Hg
Acid Value 5.00 max. KOH/g
Vapor Pressure 0.000125 mmHg @ 25.00 °C. (est)
Flash Point 273.00 °F. TCC ( 133.89 °C. )
logP (o/w) 2.370 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIng['cosmetic data2', 'cosmetic data']
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 48 hour(s) at 100.00 %
Odor Description
at 100.00 %.
at 5.00 %.
Odor sample from Chem-Fleur, Inc.
Taste Description at 5.00 - 25.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-mouse LD50 > 2000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
IFRA Critical EffectDermal sensitization
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%)Category 1: Products applied to the lips
NotesIFRA FLAVOR REQUIREMENTS:
Maximised Survey-derived Daily Intakes (MSDI-EU)0.49 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)71.00 (μg/capita/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

View All Website 973-339-6242 info@adv-bio.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

View All Website +86 (0)592 5105533 info@foreverest.cn

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

O'Laughlin Industries Inc.

Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics

Leading the Flavor and Fragrance Industry since 1980.

View All Website (973) 376-4600 olcorphk@hkstar.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

Sunaux International

Buy With Confidence

We have industry leading processes and procedures to ensure nothing but the most reliable product.

View All Website 0512-57995626 johnjft@sunaux.com

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.

Synerzine is a leading supplier of flavor and fragrance ingredients.

View All Website (404) 524-6744 info@synerzine.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

View All Website +1 (262) 995.8668 info@wholechem.com

Potential Uses

FR balsam FR cassia FR cherry FL chocolate cacao FR cinnamon FR clove FR gingerbread FR honey FR peru balsam FR raspberry FR spice FL/FR tarragon oil replacer FR tonka bean FR vanilla FR woody

Natural Occurrence

basil plant cassia PMC cassia bark cassia bark oil china @ 0.79% Data cassia leaf oil china @ 0.79% Data cinnamon bark oil (cinnamomum zeylanicum blume) sri lauka @ 0.30-0.80% Data cinnamon bark oil ceylon @ 0.79% Data cinnamon ceylon cinnamon bark

Synonyms

cinnamaldehyde, 2-methoxy- cinnamaldehyde, o-methoxy- o- methoxy cinnamaldehyde o- methoxy cinnamic aldehyde o- methoxy cinnamic aldehyde mixture in cinnamic aldehyde ortho- methoxy cinnamic aldehyde natural methoxy cinnamic aldehyde ortho / cinnamic aldehyde 50% blend methoxy cinnamic aldehyde ortho crystals natural o- methoxy cinnamic aldehyde, natural o- methoxy-cinnamaldehyde ortho- methoxy-cinnamaldehyde 3-(2- methoxy-phenyl)-propenal 2- methoxycinnamaldehyde 2'- methoxycinnamaldehyde o- methoxycinnamaldehyde methoxycinnamaldehyde, o- nat.o- methoxycinnamalhyde o- methoxycinnamic aldehyde ortho- methoxycinnamic aldehyde o- methoxycinnamic aldehyde natural beta-ortho- methoxyphenyl acrolein 3-o- methoxyphenyl-2-propenal 3-ortho- methoxyphenyl-2-propenal beta-(ortho- methoxyphenyl) acrolein 3-(2- methoxyphenyl)-2-propenal beta-(o- methoxyphenyl)acrolein 3-(2- methoxyphenyl)acrylaldehyde 3-(2- methoxyphenyl)prop-2-enal beta-o- methoxyphenylacrolein 2- propenal, 3-(2-methoxyphenyl)- PubMed: A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. PubMed: Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids. PubMed: Identification of Toxicants in Cinnamon-Flavored Electronic Cigarette Refill Fluids. PubMed: 2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction. PubMed: Proton pumping ATPase mediated fungicidal activity of two essential oil components. PubMed: 2-Methoxycinnamaldehyde inhibits tumor angiogenesis by suppressing Tie2 activation. PubMed: [Chemical constituents from roots of Andrographis paniculata]. PubMed: Platelet anti-aggregation activities of compounds from Cinnamomum cassia. PubMed: Pressurized liquid extraction and GC-MS analysis for simultaneous determination of seven components in Cinnamomum cassia and the effect of sample preparation. PubMed: Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation. PubMed: 2-methoxycinnamaldehyde reduces IL-1beta-induced prostaglandin production in rat cerebral endothelial cells. PubMed: [Effect of 2-methoxycinnamaldehyde on activity of COX and PGE2 release in cerebral microvascular endothelial cells stimulated by IL-1]. PubMed: Potentiation of antifungal activity of amphotericin B by essential oil from Cinnamomum cassia. PubMed: Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. PubMed: Distribution of MCA-coated grits in maize fields after high wheel tractor application for disrupting orientation of Diabrotica virgifera virgifera LeConte. PubMed: Comparison of adult corn rootworm (Coleoptera: Chrysomelidae) sampling methods. PubMed: Bioactive aromatic compounds from leaves and stems of Vanilla fragrans. PubMed: Control of Aspergillus flavus in maize with plant essential oils and their components. PubMed: Metabolism of the cinnamon constituent o-methoxycinnamaldehyde in the rat.