Identification

Namehorehound
IUPACmarrubium vulgare
CAS Number977001-59-4
FDA UNIISearch

Regulatory

FDA Mainterm (SATF)977001-59-4 ; HOREHOUND (MARRUBIUM VULGARE L.)
FDA RegulationFDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE

Physical Properties

Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspices, other natural seasonings and flavorings
Recommendation for horehound usage levels up tonot for fragrance use.
Recommendation for horehound flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

bronchitis

Natural Occurrence

marrubium vulgare

Synonyms

hoar hound hoarhound white horehound horehound, common horehound, white horehound, woolly marrubium vulgare PubMed: Chemical constituents of Marrubium vulgare as potential inhibitors of nitric oxide and respiratory burst. PubMed: Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare. PubMed: Marrubium vulgare L. methanolic extract inhibits inflammatory response and prevents cardiomyocyte fibrosis in isoproterenol-induced acute myocardial infarction in rats. PubMed: Anti-Trypanosoma cruzi activity of 10 medicinal plants used in northeast Mexico. PubMed: Cardioprotective effect of methanolic extract of Marrubium vulgare L. on isoproterenol-induced acute myocardial infarction in rats. PubMed: Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist. PubMed: Ethnobotany of medicinal plants used in Xalpatlahuac, Guerrero, México. PubMed: Mercury localization and speciation in plants grown hydroponically or in a natural environment. PubMed: Use of pyrogallol red and pyranine as probes to evaluate antioxidant capacities towards hypochlorite. PubMed: Molluscicidal and Mosquitocidal activities of the essential oils of Thymus capitatus Hoff. et Link. and Marrubium vulgare L. PubMed: Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants. PubMed: Compositional analysis and in vivo anti-diabetic activity of wild Algerian Marrubium vulgare L. infusion. PubMed: The in-vitro evaluation of antibacterial, antifungal and cytotoxic properties of Marrubium vulgare L. essential oil grown in Tunisia. PubMed: Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae). PubMed: Antimicrobial activity of Northwestern Mexican plants against Helicobacter pylori. PubMed: Antihepatotoxic effect of marrubium vulgare and withania somnifera extracts on carbon tetrachloride-induced hepatotoxicity in rats. PubMed: A new monoterpene acid from Marrubium vulgare with potential antihepatotoxic activity. PubMed: Antibacterial activity of water extracts and essential oils of various aromatic plants against Paenibacillus larvae, the causative agent of American Foulbrood. PubMed: Antioxidant activity and total phenolic content of 24 Lamiaceae species growing in Iran. PubMed: Activity of ladanein on leukemia cell lines and its occurrence in Marrubium vulgare. PubMed: Mercury in soils and plants in an abandoned cinnabar mining area (SW Spain). PubMed: The ecological aspect of ethnobotany and ethnopharmacology of population in Bosnia and Herzegovina. PubMed: Pilot study investigating the ability of an herbal composite to alleviate clinical signs of respiratory dysfunction in horses with recurrent airway obstruction. PubMed: Accumulation of furanic labdane diterpenes in Marrubium vulgare and Leonurus cardiaca. PubMed: Marrubium vulgare extract inhibits human-LDL oxidation and enhances HDL-mediated cholesterol efflux in THP-1 macrophage. PubMed: Antioedematogenic effect of marrubiin obtained from Marrubium vulgare. PubMed: Evaluation of antimicrobial activity of selected plant extracts by rapid XTT colorimetry and bacterial enumeration. PubMed: Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. PubMed: Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells. PubMed: Bactericidal activity of organic extracts from Flourensia cernua DC against strains of Mycobacterium tuberculosis. PubMed: Mercury bioaccumulation and phytotoxicity in two wild plant species of Almadén area. PubMed: Analgesic potential of marrubiin derivatives, a bioactive diterpene present in Marrubium vulgare (Lamiaceae). PubMed: Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics. PubMed: Natural phenylpropanoids inhibit lipoprotein-induced endothelin-1 secretion by endothelial cells. PubMed: Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat. PubMed: Characterisation of marrubenol, a diterpene extracted from Marrubium vulgare, as an L-type calcium channel blocker. PubMed: Natural phenylpropanoids protect endothelial cells against oxidized LDL-induced cytotoxicity. PubMed: The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare. PubMed: Marruboside, a new phenylethanoid glycoside from Marrubium vulgare L. PubMed: Comparison of the total antioxidant content of 30 widely used medicinal plants of New Mexico. PubMed: Isolation and pharmacological activity of phenylpropanoid esters from Marrubium vulgare. PubMed: Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants. PubMed: Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat. PubMed: Analysis of the antinociceptive properties of marrubiin isolated from Marrubium vulgare. PubMed: Analgesic profile of hydroalcoholic extract obtained from Marrubium vulgare. PubMed: Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway. PubMed: [Chemical tests with Marrubium species. Official data on Marubii herba in Pharmacopoeia Hungarica VII]. PubMed: Antispasmodic effects of hydroalcoholic extract of Marrubium vulgare on isolated tissues. PubMed: Hypoglycemic effect of plants used in Mexico as antidiabetics. PubMed: [Pharmacologic spectrum of Marrubium vulgare L]. PubMed: [Marrubium vulgare and its pharmaceutical uses. I]. PubMed: ISOLATION OF MARRUBIN, A STEROL, AND A SESQUITERPENE FROM MARRUBIUM VULGARE. PubMed: [ON THE ABORTIVE PROPERTIES OF WHITE HOREHOUND (MARRUBIUM VULGARE L.)]. PubMed: [Resin of the white horehound (Marrubium vulgare L). II]. PubMed: [Resin and wax of white marrubium (Marrubium vulgare L.)]. PubMed: [Marrubium vulgare]. PubMed: [Not Available].