Identification

Namevalencene
IUPAC(2R)-8,8,8a-trimethyl-2-prop-1-en-2-yl-1,2,3,4,6,7-hexahydronaphthalene
EINECS225-047-6
FDA UNIISearch
Molecular FormulaC15 H24
Molecular Weight204.35628000
MDL NumberMFCD00075884
Nikkaji NumberJ2.117.859D
Beilstein3539153
CoE Number11030

Regulatory

JECFA Food Flavoring1337 valencene
DG SANTE Food Flavourings01.017 valencene
FEMA Number3443
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)4630-07-3 ; VALENCENE

Physical Properties

Appearance pale yellow to yellow clear liquid (est)
Assay 94.00 to 100.00 sum of isomers
Food Chemicals Codex Listed No
Specific Gravity 0.91000 to 0.92200 @ 25.00 °C.
Pounds per Gallon - (est). 7.572 to 7.672
Refractive Index 1.49800 to 1.51000 @ 20.00 °C.
Boiling Point 123.00 °C. @ 11.00 mm Hg, 274.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.011000 mmHg @ 25.00 °C. (est)
Flash Point 212.00 °F. TCC ( 100.00 °C. )
logP (o/w) 6.494 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium ,
Substantivity 336 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
sweet, fresh citrus, grapefruit, woody, orange
Orange, citrus, woody
sweet fresh citrus grapefruit woody orange asprin dry green oily
Odor sample from CA Aromatics Company Inc.
Taste Description
orange citrus fruity juicy citrus peel peely woody
Characteristic juicy orange, slightly woody backnotes
orange, citrusy, warm and woody
orange, sweet, woody

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 [sex: M] > 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for valencene usage levels up to1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)53.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)26.00 (μg/capita/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Associate Allied Chemicals

Quality, Service and Values

Our aim is to become a reliable one-stop shop for our customers.

View All Website +91 22 2419 8800 aacipl@aacipl.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Bedoukian Research, Inc.

Perfecting the Art of Chemistry

Working closely with our customers to meet their requirements.

View All Website 1-203-830-4000 customerservice@bedoukian.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Cvista

Cutting-edge technology and quality

Our flexibility allows us to quickly react to changing customer needs.

View All Website 813-405-3000 bcarter@cvista.com

FCI SAS

Inspired by Nature

At FCI customer service is not a department it’s an attitude.

View All Website +33 (0)1 34 25 58 10 info@fcifr.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Global Essence Inc.

Preferred Partner

Accommodate each customers unique needs.

View All Website 001 732 677 1100 info@globalessenceuk.com

FRUTAROM USA INC,

Flavor & Specialty Ingredients

Your preferred partner for flavour and fragrance success.

View All Website +44 (0) 1429 863 222 Sales.IFFIngredients@iff.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

The Lermond Company

Your Sourcing Resource

The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.

View All Website 201-896-3300 info@lermond.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

Potential Uses

FR citrus dry FR grapefruit FR orange FR oriental FR woody

Natural Occurrence

amyris wood oil @ trace% Data blood orange oil (citrus sinensis l. var. sanguinello) italy @ 0.309% Data blood orange oil (citrus sinensis l. var. tarocco) italy @ 0.093% Data blood orange oil italy @ 0.177% Data cascarilla bark oil @ 0.18% Data cedarwood oil texas @ 0.10% Data cedarwood oil virginia @ 0.10% Data citrus fruits PMC clary sage oil spain @ 2.84% Data cocoa grapefruit oil c.p. russia @ 0.06% Data grapefruit oil c.p. russia @ 0.06% Data grapefruit oil c.p. russia @ 0.08% Data grapefruit oil c.p. russia @ 0.13% Data hyptis suaveolens (l.) poit. oil mali @ 0.60-1.00% Data labdanum oil @ 0.16% Data lemon tissue culture lime oil CO2 extract mexico @ 0.10% Data mandarin fruit orange fruit orange fruit juice orange oil c.p. brazil @ 0.13-0.27% Data orange peel oil bitter brazil @ 0.29% Data orange peel oil sweet c.p. blond italy @ 0.038% Data orange peel oil sweet c.p. blond italy @ 0.046% Data orange peel oil sweet c.p. blond italy @ 0.067% Data orange peel oil sweet c.p. blond italy @ 0.101% Data orange peel oil sweet c.p. blond italy @ 0.174% Data orange peel oil sweet c.p. florida @ 0.05% Data orange peel oil sweet c.p. valencia @ 0.05% Data orange pericarp oil oregano shoot oil pepper oil black india @ trace% Data rosemary sage oil albania @ 0.10% Data tagete oil CO2 extract @ 0.57% Data tansy oil marocco @ 0.50% Data thyme oil red CO2 extract @ 0.01% Data

Synonyms

4a,5- dimethyl-3-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene 4alpha,10alpha- dimethyl-6beta-isopropyl-delta1,9-octalin 5,6- dimethyl-8-(1-methylvinyl)bicyclo[4.4.0]dec-1-ene eremophila-1(10),11-diene 4betaH,5alpha- eremophila-1(10),11-diene (1R,7R,8aS)- 1,2,3,5,6,7,8,8a- octahydro-1,8a-dimethyl-7-(1-methyl ethenyl) naphthalene (1R-(1alpha, 7beta,8alpha))-1,2,3,5,6,7,8,8a- octahydro-1,8a-dimethyl-7-(1-methyl vinyl) naphthalene 1,2,3,5,6,7,8,8alpha- octahydro-1,8alpha-dimethyl-7-1-methyl ethenyl napthalene octahydrodimethyl methyl vinyl naphthalene 3-iso propenyl-4a,5-dimethyl-1,2,3,4,4a,5,6,7-octahydro-naphthalene valencene (+)- valencene valencene - ex orange (50%, 60%, 70%) valencene (natural) valencene 50% natural valencene 70 valencene 75% natural valencene natural valencene, 50 - 70%, natural valencene, 70%- 80%, natural valencene, 80% min., natural valencene, natural Perfumer & Flavorist: Organolpetic Characteristics of Flavor Materials PubMed: Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris. Perfumer & Flavorist: Natural Valencene by Fermentation PubMed: High-density biosynthetic fuels: the intersection of heterogeneous catalysis and metabolic engineering. PubMed: Essential oil compositions and anticholinesterase activities of two edible plants Tragopogon latifolius var. angustifolius and Lycopsis orientalis. PubMed: Allylic oxidation of alkenes catalyzed by a copper-aluminum mixed oxide. PubMed: Production of (+)-valencene in the mushroom-forming fungus S. commune. PubMed: Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis). PubMed: Olfactory preference for egg laying on citrus substrates in Drosophila. PubMed: Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach. PubMed: Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene. PubMed: Modification of valencene by bio- and chemical transformation. PubMed: Challenges and pitfalls of P450-dependent (+)-valencene bioconversion by Saccharomyces cerevisiae. PubMed: Norms of valence, arousal, and dominance for 13,915 English lemmas. PubMed: Molecular characterization of a lipoxygenase from the basidiomycete mushroom Pleurotus ostreatus. PubMed: Isolation and biological activities of decanal, linalool, valencene, and octanal from sweet orange oil. PubMed: De novo synthesis of high-value plant sesquiterpenoids in yeast. PubMed: Pyrolytic formation of polycyclic aromatic hydrocarbons from sesquiterpenes. PubMed: Functional expression and characterization of sesquiterpene synthases from Artemisia annua L. using transient expression system in Nicotiana benthamiana. PubMed: Functional expression of a valencene dioxygenase from Pleurotus sapidus in E. coli. PubMed: Influence of various growth parameters on fungal growth and volatile metabolite production by indoor molds. PubMed: Transcriptional analysis of late ripening stages of grapevine berry. PubMed: In vitro anthelmintic activity of the essential oils of Zanthoxylum zanthoxyloides and Newbouldia laevis against Strongyloides ratti. PubMed: (+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. PubMed: RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes. PubMed: Biologically important eremophilane sesquiterpenes from alaska cedar heartwood essential oil and their semi-synthetic derivatives. PubMed: Harnessing yeast subcellular compartments for the production of plant terpenoids. PubMed: Volatile compounds and bioactivity of Eremurus spectabilis (Ciris), a Turkish wild edible vegetable. PubMed: Role of novel terpenes in transcutaneous permeation of valsartan: effectiveness and mechanism of action. PubMed: Anti-allergic activity of sesquiterpenes from the rhizomes of Cyperus rotundus. PubMed: Chemical composition of the essential oil of Croton gossypiifolius from Venezuela. PubMed: A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. PubMed: Catalytic oxidation of concentrated orange oil phase by synthetic metallic complexes biomimetic to MMO enzyme. PubMed: Isolation and purification of nootkatone from the essential oil of fruits of Alpinia oxyphylla Miquel by high-speed counter-current chromatography. PubMed: Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis. PubMed: Essential oils from two Lantana species with antimycobacterial activity. PubMed: Autoxidation versus biotransformation of alpha-pinene to flavors with Pleurotus sapidus: regioselective hydroperoxidation of alpha-pinene and stereoselective dehydrogenation of verbenol. PubMed: A dioxygenase of Pleurotus sapidus transforms (+)-valencene regio-specifically to (+)-nootkatone via a stereo-specific allylic hydroperoxidation. PubMed: Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system. PubMed: The bouquet of grapevine (Vitis vinifera L. cv. Cabernet Sauvignon) flowers arises from the biosynthesis of sesquiterpene volatiles in pollen grains. PubMed: Nootkatone--a biotechnological challenge. PubMed: Rational design of a minimal and highly enriched CYP102A1 mutant library with improved regio-, stereo- and chemoselectivity. PubMed: [Characterization of aroma active compounds in blood orange juice by solid phase microextraction and gas chromatography-mass spectrometry-olfactometry]. PubMed: Montanoa tomentosa glandular trichomes containing kaurenoic acids chemical profile and distribution. PubMed: Essential Oil Composition and Antibacterial Studies of Vitex negundo Linn. Extracts. PubMed: [Increase of copy number of HMG-CoA reductase and FPP synthase genes improves the amorpha4,11-diene production in engineered yeast]. PubMed: Antimicrobial activity of extractable conifer heartwood compounds toward Phytophthora ramorum. PubMed: [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood]. PubMed: Production of plant sesquiterpenes in Saccharomyces cerevisiae: effect of ERG9 repression on sesquiterpene biosynthesis. PubMed: Chemical composition of the essential oil of Pelargonium quercetorum Agnew. of Iran. PubMed: Repellent activity of fractioned compounds from Chamaecyparis nootkatensis essential oil against nymphal Ixodes scapularis (Acari: Ixodidae). PubMed: Valence isomerization of 2-phospha-4-silabicyclo[1.1.0]butane: a high-level ab initio study. PubMed: Highly efficient production of nootkatone, the grapefruit aroma from valencene, by biotransformation. PubMed: Biotransformation of citrus aromatics nootkatone and valencene by microorganisms. PubMed: Analysis of the essential oil composition from the different parts of Eryngiumglaciale Boiss. from Spain. PubMed: Headspace solid-phase microextraction-gas chromatography--mass spectrometry analysis of the volatile compounds of Evodia species fruits. PubMed: Use of novel compounds for pest control: insecticidal and acaricidal activity of essential oil components from heartwood of Alaska yellow cedar. PubMed: Bioconversion of (+)-valencene in submerged cultures of the ascomycete Chaetomium globosum. PubMed: Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3. PubMed: Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries. PubMed: Aristolochene synthase: mechanistic analysis of active site residues by site-directed mutagenesis. PubMed: Valencene synthase--a biochemical magician and harbinger of transgenic aromas. PubMed: [Chemical components of Vetiveria zizanioides volatiles]. PubMed: Structure-activity of valencenoid derivatives and their repellence to the Formosan subterranean termite. PubMed: Citrus fruit flavor and aroma biosynthesis: isolation, functional characterization, and developmental regulation of Cstps1, a key gene in the production of the sesquiterpene aroma compound valencene. PubMed: Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. PubMed: The sesquiterpenoid nootkatone and the absolute configuration of a dibromo derivative. PubMed: Volatiles from leaves, fruits, and virgin oil from Olea europaea Cv. Olivastra Seggianese from Italy. PubMed: Monitoring and fast detection of mycotoxin-producing fungi based on headspace solid-phase microextraction and headspace sorptive extraction of the volatile metabolites. PubMed: [Chemical constituents in volatile oil from fruits of Alpinia oxyphylla Miq]. PubMed: Influence of flavour absorption by food-packaging materials (low-density polyethylene, polycarbonate and polyethylene terephthalate) on taste perception of a model solution and orange juice. PubMed: Volatile sesquiterpene hydrocarbons characteristic for Penicillium roqueforti strains producing PR toxin. PubMed: Effects of pulsed electric field processing and storage on the quality and stability of single-strength orange juice. PubMed: Germacrene A is a product of the aristolochene synthase-mediated conversion of farnesylpyrophosphate to aristolochene. PubMed: Volatile chemicals identified in extracts from newly hybrid citrus, dekopon (Shiranuhi mandarin Suppl. J.). PubMed: Chemical variability of the volatile metabolites from the Caribbean corals of the genus Gorgonia. PubMed: Accumulation of the sesquiterpenes nootkatone and valencene by callus cultures of Citrus paradisi, Citrus limonia and Citrus aurantium. PubMed: Regioselective biotransformation of valencene in cell suspension cultures of Citrus sp.