hinokiresinol
4,4'-(1E)-penta-1,4-diene-1,3-diyldiphenol
Identification
| Name | hinokiresinol |
| IUPAC | 4-[(1E)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol |
| CAS Number | 17676-24-3 |
| FDA UNII | Search |
| Molecular Formula | C17 H16 O2 |
| Molecular Weight | 252.31292000 |
| Nikkaji Number | J16.129B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 429.40 °C. @ 760.00 mm Hg (est) |
| Flash Point | 399.00 °F. TCC ( 203.80 °C. ) (est) |
| logP (o/w) | 3.710 (est) |
| Soluble in | water, 6.587 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for hinokiresinol usage levels up to | not for fragrance use. |
| Recommendation for hinokiresinol flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Potential Uses
Natural Occurrence
Synonyms
4,4'-(3-
ethenyl-1-propene-1,3-diyl)-bisphenol
rac-
hinokiresinol
4-[(1E)-3-(4-
hydroxyphenyl)penta-1,4-dienyl]phenol
4-[1-[(E)-4-
hydroxystyryl]allyl]phenol
4,4'-(1E)-
penta-1,4-diene-1,3-diyldiphenol
4,4'-[(1E)-1,4-
pentadiene-1,3-diyl]diphenol
phenol, 4,4'-(3-ethenyl-1-propene-1,3-diyl)bis-, (E)-
phenol, 4,4'-(3-vinylpropenylene)di-, (E)-
phenol, 4,4'-[(1E)-3-ethenyl-1-propene-1,3-diyl]bis-
4,4'-[(E)-3-
vinyl-1-propene-1,3-diyl]bis[phenol]
PubMed:
Differential anti-ischemic efficacy and therapeutic time window of trans- and cis-hinokiresinols: stereo-specific antioxidant and anti-inflammatory activities.
PubMed:
A heartwood norlignan, (E)-hinokiresinol, is formed from 4-coumaryl 4-coumarate by a Cryptomeria japonica enzyme preparation.
PubMed:
Lignans in resin of Araucaria angustifolia by gas chromatography/mass spectrometry.
PubMed:
Stereochemistry of cis- and trans-hinokiresinol and their estrogen-like activity.
PubMed:
Differential anti-ischemic efficacy and therapeutic time window of trans- and cis-hinokiresinols: stereo-specific antioxidant and anti-inflammatory activities.
PubMed:
Iridium-catalyzed enantioselective allylic vinylation.
PubMed:
Subunit composition of hinokiresinol synthase controls enantiomeric selectivity in hinokiresinol formation.
PubMed:
(-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production.
PubMed:
Discriminating the indistinguishable sapwood from heartwood in discolored ancient wood by direct molecular mapping of specific extractives using time-of-flight secondary ion mass spectrometry.
PubMed:
The subunit composition of hinokiresinol synthase controls geometrical selectivity in norlignan formation.
PubMed:
Antioxidant and antiatherogenic activity of cis-Hinokiresinol from Trapa pseudoincisa.
PubMed:
Carroll rearrangement to construct the norneolignan skeleton.
PubMed:
Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide.
PubMed:
Norlignans with Hyaluronidase Inhibitory Activity from Anemarrhena asphodeloides.
PubMed:
Hinokiresinol inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction.
PubMed:
Hinokiresinol is not a precursor of agatharesinol in the norlignan biosynthetic pathway in Japanese cedar.
PubMed:
Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
PubMed:
Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy.
PubMed:
Lignans in resin of Araucaria angustifolia by gas chromatography/mass spectrometry.
PubMed:
cis-hinokiresinol, a norlignan from Anemarrhena asphodeloides, inhibits angiogenic response in vitro and in vivo.
PubMed:
First in vitro norlignan formation with Asparagus officinalis enzyme preparation.
PubMed:
Stereochemistry of cis- and trans-hinokiresinol and their estrogen-like activity.